A human cytomegalovirus early gene has three inducible promoters that are regulated differentially at various times after infection
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Proteasome-independent disruption of PML oncogenic domains (PODs), but not covalent modification by SUMO-1, is required for human cytomegalovirus immediate-early protein IE1 to inhibit PML-mediated transcriptional repression.Ability of the human cytomegalovirus IE1 protein to modulate sumoylation of PML correlates with its functional activities in transcriptional regulation and infectivity in cultured fibroblast cellsHerpesvirus Late Gene Expression: A Viral-Specific Pre-initiation Complex Is KeyAntisense transcription in the human cytomegalovirus transcriptome.Identification, characterization, and sequence analysis of a cDNA encoding a phosphoprotein of human herpesvirus 6Activation of transcription of the human cytomegalovirus early UL4 promoter by the Ets transcription factor binding element.Transcription factor Sp1 mediates cell-specific trans-activation of the human cytomegalovirus DNA polymerase gene promoter by immediate-early protein IE86 in glioblastoma U373MG cells.Defective growth correlates with reduced accumulation of a viral DNA replication protein after low-multiplicity infection by a human cytomegalovirus ie1 mutant.Two Sp1/Sp3 binding sites in the major immediate-early proximal enhancer of human cytomegalovirus have a significant role in viral replication.Role of regulatory elements and the MAPK/ERK or p38 MAPK pathways for activation of human cytomegalovirus gene expression.Construction of a self-excisable bacterial artificial chromosome containing the human cytomegalovirus genome and mutagenesis of the diploid TRL/IRL13 gene.The human cytomegalovirus gene products essential for late viral gene expression assemble into prereplication complexes before viral DNA replication.Cytomegalovirus immediate early genes prevent the inhibitory effect of cyclosporin A on interleukin 2 gene transcription.Analysis and mapping of a family of 3'-coterminal transcripts containing coding sequences for human cytomegalovirus open reading frames UL93 through UL99.Isolation and characterization of a low-abundance splice variant from the human cytomegalovirus major immediate-early gene region.The human cytomegalovirus UL98 gene transcription unit overlaps with the pp28 true late gene (UL99) and encodes a 58-kilodalton early protein.Multiple regulatory events influence human cytomegalovirus DNA polymerase (UL54) expression during viral infectionThe late promoter of the human cytomegalovirus viral DNA polymerase processivity factor has an impact on delayed early and late viral gene products but not on viral DNA synthesisThe IE2 regulatory protein of human cytomegalovirus induces expression of the human transforming growth factor beta1 gene through an Egr-1 binding site.The role of ATF in regulating the human cytomegalovirus DNA polymerase (UL54) promoter during viral infection.RNA interference-mediated targeting of human cytomegalovirus immediate-early or early gene products inhibits viral replication with differential effects on cellular functions.A cis element between the TATA Box and the transcription start site of the major immediate-early promoter of human cytomegalovirus determines efficiency of viral replication.Noncanonical TATA sequence in the UL44 late promoter of human cytomegalovirus is required for the accumulation of late viral transcripts.Identification of sequence elements in the human cytomegalovirus DNA polymerase gene promoter required for activation by viral gene products.The human cytomegalovirus 86-kilodalton immediate-early 2 protein: synthesis as a precursor polypeptide and interaction with a 75-kilodalton protein of probable viral origin.Use of recombinant virus to assess human cytomegalovirus early and late promoters in the context of the viral genome.Protein-protein interactions between human cytomegalovirus IE2-580aa and pUL84 in lytically infected cells.Structural organization, expression, and functional characterization of the murine cytomegalovirus immediate-early gene 3Human cytomegalovirus ie2 negatively regulates alpha gene expression via a short target sequence near the transcription start siteA cis-acting element in the major immediate-early (IE) promoter of human cytomegalovirus is required for negative regulation by IE2.Characterization of a human cytomegalovirus 1.6-kilobase late mRNA and identification of its putative protein product.ICP22 homolog of equine herpesvirus 1: expression from early and late promoters.Transactivation of the cytomegalovirus ICP36 gene promoter requires the alpha gene product TRS1 in addition to IE1 and IE2Characterization of human cytomegalovirus UL84 early gene and identification of its putative protein productFunctional analysis of the true late human cytomegalovirus pp28 upstream promoter: cis-acting elements and viral trans-acting proteins necessary for promoter activation.An early gene maps within and is 3' coterminal with the immediate-early gene of equine herpesvirus 1.The functionally active IE2 immediate-early regulatory protein of human cytomegalovirus is an 80-kilodalton polypeptide that contains two distinct activator domains and a duplicated nuclear localization signalThe human cytomegalovirus 2.7-kilobase RNA promoter contains a functional binding site for the adenovirus major late transcription factor.Transactivation of a human cytomegalovirus early promoter by gene products from the immediate-early gene IE2 and augmentation by IE1: mutational analysis of the viral proteins.Guinea pig cytomegalovirus immediate-early transcription.
P2860
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P2860
A human cytomegalovirus early gene has three inducible promoters that are regulated differentially at various times after infection
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
A human cytomegalovirus early ...... various times after infection
@ast
A human cytomegalovirus early ...... various times after infection
@en
type
label
A human cytomegalovirus early ...... various times after infection
@ast
A human cytomegalovirus early ...... various times after infection
@en
prefLabel
A human cytomegalovirus early ...... various times after infection
@ast
A human cytomegalovirus early ...... various times after infection
@en
P2093
P2860
P1433
P1476
A human cytomegalovirus early ...... various times after infection
@en
P2093
C L Malone
M F Stinski
P2860
P304
P407
P577
1989-01-01T00:00:00Z