Transactivation of a human cytomegalovirus early promoter by gene products from the immediate-early gene IE2 and augmentation by IE1: mutational analysis of the viral proteins.
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Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: induction of interferon-responsive RNAsProteasome-independent disruption of PML oncogenic domains (PODs), but not covalent modification by SUMO-1, is required for human cytomegalovirus immediate-early protein IE1 to inhibit PML-mediated transcriptional repression.Ability of the human cytomegalovirus IE1 protein to modulate sumoylation of PML correlates with its functional activities in transcriptional regulation and infectivity in cultured fibroblast cellsCloning and mutagenesis of a herpesvirus genome as an infectious bacterial artificial chromosomeAn HIV feedback resistor: auto-regulatory circuit deactivator and noise bufferOpen reading frame UL26 of human cytomegalovirus encodes a novel tegument protein that contains a strong transcriptional activation domain.Human cytomegalovirus and human herpesvirus 6 genes that transform and transactivateActivation of transcription of the human cytomegalovirus early UL4 promoter by the Ets transcription factor binding element.Human cytomegalovirus latency-associated protein pORF94 is dispensable for productive and latent infection.Effects of human cytomegalovirus major immediate-early proteins in controlling the cell cycle and inhibiting apoptosis: studies with ts13 cellsThe phosphorylation status of the serine-rich region of the human cytomegalovirus 86-kilodalton major immediate-early protein IE2/IEP86 affects temporal viral gene expression.Transcription factor Sp1 mediates cell-specific trans-activation of the human cytomegalovirus DNA polymerase gene promoter by immediate-early protein IE86 in glioblastoma U373MG cells.Defective growth correlates with reduced accumulation of a viral DNA replication protein after low-multiplicity infection by a human cytomegalovirus ie1 mutant.Identification of positive and negative regulatory regions involved in regulating expression of the human cytomegalovirus UL94 late promoter: role of IE2-86 and cellular p53 in mediating negative regulatory function.Phosphorylation of the human cytomegalovirus 86-kilodalton immediate-early protein IE2.A cis repression sequence adjacent to the transcription start site of the human cytomegalovirus US3 gene is required to down regulate gene expression at early and late times after infectionElimination of ie1 significantly attenuates murine cytomegalovirus virulence but does not alter replicative capacity in cell cultureThe human cytomegalovirus major immediate-early distal enhancer region is required for efficient viral replication and immediate-early gene expression.Covalent modification of the transactivator protein IE2-p86 of human cytomegalovirus by conjugation to the ubiquitin-homologous proteins SUMO-1 and hSMT3b.The human cytomegalovirus IE86 protein can block cell cycle progression after inducing transition into the S phase of permissive cells.A strong negative transcriptional regulatory region between the human cytomegalovirus UL127 gene and the major immediate-early enhancer.Reactivation of the human cytomegalovirus major immediate-early regulatory region and viral replication in embryonal NTera2 cells: role of trichostatin A, retinoic acid, and deletion of the 21-base-pair repeats and modulator.Human cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-γRequirement of multiple cis-acting elements in the human cytomegalovirus major immediate-early distal enhancer for viral gene expression and replication.Alternative splicing of the human cytomegalovirus major immediate-early genes affects infectious-virus replication and control of cellular cyclin-dependent kinase.Human herpesvirus 6 major immediate early promoter has strong activity in T cells and is useful for heterologous gene expression.Evidence that the human cytomegalovirus IE2-86 protein binds mdm2 and facilitates mdm2 degradationInhibition of cellular DNA synthesis by the human cytomegalovirus IE86 protein is necessary for efficient virus replication.Strain variations in single amino acids of the 86-kilodalton human cytomegalovirus major immediate-early protein (IE2) affect its functional and biochemical properties: implications of dynamic protein conformation.Absence of IE1 p72 protein function during low-multiplicity infection by human cytomegalovirus results in a broad block to viral delayed-early gene expression.Role of the human cytomegalovirus major immediate-early promoter's 19-base-pair-repeat cyclic AMP-response element in acutely infected cells.Cytomegalovirus immediate early genes prevent the inhibitory effect of cyclosporin A on interleukin 2 gene transcription.Analysis of splice variants of the immediate-early 1 region of human cytomegalovirus.The IE2 60-kilodalton and 40-kilodalton proteins are dispensable for human cytomegalovirus replication but are required for efficient delayed early and late gene expression and production of infectious virus.Human cytomegalovirus UL102 geneIsolation and characterization of a low-abundance splice variant from the human cytomegalovirus major immediate-early gene region.The human cytomegalovirus UL98 gene transcription unit overlaps with the pp28 true late gene (UL99) and encodes a 58-kilodalton early protein.Multiple regulatory events influence human cytomegalovirus DNA polymerase (UL54) expression during viral infectionThe autoregulatory and transactivating functions of the human cytomegalovirus IE86 protein use independent mechanisms for promoter binding.Cellular or viral protein binding to a cytomegalovirus promoter transcription initiation site: effects on transcription.
P2860
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P2860
Transactivation of a human cytomegalovirus early promoter by gene products from the immediate-early gene IE2 and augmentation by IE1: mutational analysis of the viral proteins.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Transactivation of a human cyt ...... nalysis of the viral proteins.
@ast
Transactivation of a human cyt ...... nalysis of the viral proteins.
@en
type
label
Transactivation of a human cyt ...... nalysis of the viral proteins.
@ast
Transactivation of a human cyt ...... nalysis of the viral proteins.
@en
prefLabel
Transactivation of a human cyt ...... nalysis of the viral proteins.
@ast
Transactivation of a human cyt ...... nalysis of the viral proteins.
@en
P2093
P2860
P1433
P1476
Transactivation of a human cyt ...... nalysis of the viral proteins.
@en
P2093
C L Malone
D H Vesole
M F Stinski
P2860
P304
P407
P577
1990-04-01T00:00:00Z