Notch inhibits osteoblast differentiation and causes osteopenia.
about
Truncating mutations in the last exon of NOTCH2 cause a rare skeletal disorder with osteoporosisNotch signaling deregulation in multiple myeloma: A rational molecular targetNotch regulation of bone development and remodeling and related skeletal disordersPhysiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1miRNA-34c regulates Notch signaling during bone developmentNotch1 represses osteogenic pathways in aortic valve cellsNotch signaling in osteocytes differentially regulates cancellous and cortical bone remodelingAberrant Notch Signaling in the Bone Marrow Microenvironment of Acute Lymphoid Leukemia Suppresses Osteoblast-Mediated Support of Hematopoietic Niche Function.Notch and the skeleton.RBP-Jκ-dependent Notch signaling is required for murine articular cartilage and joint maintenance.RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal developmentConnective tissue growth factor is a target of notch signaling in cells of the osteoblastic lineage.NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB.Maintenance of Bone Homeostasis by DLL1-Mediated Notch SignalingIntermittent activation of notch signaling promotes bone formation.Multiple myeloma mesenchymal stromal cells: Contribution to myeloma bone disease and therapeuticsConnective tissue growth factor is required for skeletal development and postnatal skeletal homeostasis in male mice.Notch activation as a driver of osteogenic sarcoma.Connective tissue growth factor (CTGF) transactivates nuclear factor of activated T-cells (NFAT) in cells of the osteoblastic lineageHES1 (hairy and enhancer of split 1) is a determinant of bone massGalectin-3 inhibits osteoblast differentiation through notch signaling.Reciprocal regulation of Notch and nuclear factor of activated T-cells (NFAT) c1 transactivation in osteoblastsHajdu-Cheney syndrome: a review.Notch signaling and the bone marrow hematopoietic stem cell niche.Jagged1 is essential for osteoblast development during maxillary ossification.Osteosclerosis owing to Notch gain of function is solely Rbpj-dependentTransient gamma-secretase inhibition accelerates and enhances fracture repair likely via Notch signaling modulationNotch inhibits chondrogenic differentiation of mesenchymal progenitor cells by targeting Twist1.Nemo-like kinase inhibits osteoblastogenesis by suppressing bone morphogenetic protein and WNT canonical signaling.mTORC1 Prevents Preosteoblast Differentiation through the Notch Signaling Pathway.TNF-induced osteoclastogenesis and inflammatory bone resorption are inhibited by transcription factor RBP-J.Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone developmentNotch signaling in skeletal health and disease.Genetic mouse models for bone studies--strengths and limitationsNotch2 Signaling Regulates the Proliferation of Murine Bone Marrow-Derived Mesenchymal Stem/Stromal Cells via c-Myc Expression.Canonical Notch activation in osteocytes causes osteopetrosis.Hajdu Cheney Mouse Mutants Exhibit Osteopenia, Increased Osteoclastogenesis, and Bone Resorption.Osteoblast lineage-specific effects of notch activation in the skeletonNotch suppresses nuclear factor of activated T cells (NFAT) transactivation and Nfatc1 expression in chondrocytesDevelopment of the endochondral skeleton
P2860
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P2860
Notch inhibits osteoblast differentiation and causes osteopenia.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Notch inhibits osteoblast differentiation and causes osteopenia.
@en
type
label
Notch inhibits osteoblast differentiation and causes osteopenia.
@en
prefLabel
Notch inhibits osteoblast differentiation and causes osteopenia.
@en
P2093
P2860
P356
P1433
P1476
Notch inhibits osteoblast differentiation and causes osteopenia.
@en
P2093
Anna Smerdel-Ramoya
Deena Durant
Ernesto Canalis
Freddy Radtke
Lisa Stadmeyer
Stefano Zanotti
P2860
P304
P356
10.1210/EN.2008-0140
P407
P577
2008-04-17T00:00:00Z