Genetic evidence that acute morphologic transformation, induction of cellular DNA synthesis, and focus formation are mediated by a single activity of the bovine papillomavirus E5 protein
about
Mechanisms of cell transformation by papillomavirus E5 proteins.The bovine papillomavirus constitutive enhancer is essential for viral transformation, DNA replication, and the maintenance of latencyStructural role of the conserved cysteines in the dimerization of the viral transmembrane oncoprotein E5.Cellular transformation by a transmembrane peptide: structural requirements for the bovine papillomavirus E5 oncoprotein.Mutational analysis of the interaction between the bovine papillomavirus E5 transforming protein and the endogenous beta receptor for platelet-derived growth factor in mouse C127 cells.Mutational analysis of human papillomavirus type 11 E5a oncoproteinIdentification of amino acids in the transmembrane and juxtamembrane domains of the platelet-derived growth factor receptor required for productive interaction with the bovine papillomavirus E5 protein.Hydrophobic Mismatch Drives the Interaction of E5 with the Transmembrane Segment of PDGF Receptor.Specific interaction between the bovine papillomavirus E5 transforming protein and the beta receptor for platelet-derived growth factor in stably transformed and acutely transfected cellsGenetic definition of a new bovine papillomavirus type 1 open reading frame, E5B, that encodes a hydrophobic protein involved in altering host-cell protein processing.Inhibition of cervical carcinoma cell line proliferation by the introduction of a bovine papillomavirus regulatory geneA glutamine residue in the membrane-associating domain of the bovine papillomavirus type 1 E5 oncoprotein mediates its binding to a transmembrane component of the vacuolar H(+)-ATPase.The central hydrophobic domain of the bovine papillomavirus E5 transforming protein can be functionally replaced by many hydrophobic amino acid sequences containing a glutamineThe E5 gene product of rhesus papillomavirus is an activator of endogenous Ras and phosphatidylinositol-3'-kinase in NIH 3T3 cells.Platelet-derived growth factor receptor can mediate tumorigenic transformation by the bovine papillomavirus E5 protein.Biologic properties and nucleotide sequence analysis of human papillomavirus type 51.Biological properties of the deer papillomavirus E5 gene in mouse C127 cells: growth transformation, induction of DNA synthesis, and activation of the platelet-derived growth factor receptorBovine papillomavirus E2 repressor mutant displays a high-copy-number phenotype and enhanced transforming activity.Localization of bovine papillomavirus type 1 E5 protein to transformed basal keratinocytes and permissive differentiated cells in fibropapilloma tissue.Stable association between the bovine papillomavirus E5 transforming protein and activated platelet-derived growth factor receptor in transformed mouse cells.Bovine papillomaviruses, papillomas and cancer in cattle.The putative E5 open reading frame of cottontail rabbit papillomavirus is dispensable for papilloma formation in domestic rabbits.Expression cloning of multiple human cDNAs that complement the phenotypic defects of ataxia-telangiectasia group D fibroblasts.Activation of the platelet-derived growth factor receptor by the bovine papillomavirus E5 transforming protein.Molecular cloning, analysis, and chromosomal localization of a mouse genomic sequence related to the human papillomavirus type 18 E5 region.
P2860
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P2860
Genetic evidence that acute morphologic transformation, induction of cellular DNA synthesis, and focus formation are mediated by a single activity of the bovine papillomavirus E5 protein
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Genetic evidence that acute mo ...... vine papillomavirus E5 protein
@en
type
label
Genetic evidence that acute mo ...... vine papillomavirus E5 protein
@en
prefLabel
Genetic evidence that acute mo ...... vine papillomavirus E5 protein
@en
P2093
P2860
P356
P1476
Genetic evidence that acute mo ...... vine papillomavirus E5 protein
@en
P2093
P2860
P304
P356
10.1128/MCB.9.12.5563
P407
P577
1989-12-01T00:00:00Z