The conserved salt bridge in human alpha-defensin 5 is required for its precursor processing and proteolytic stability
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Invariant gly residue is important for α-defensin folding, dimerization, and function: a case study of the human neutrophil α-defensin HNP1Trp-26 imparts functional versatility to human alpha-defensin HNP1Through the looking glass, mechanistic insights from enantiomeric human defensinsPeptides and Peptidomimetics for Antimicrobial Drug DesignNMR Solution Structure and Condition-Dependent Oligomerization of the Antimicrobial Peptide Human Defensin 5The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistanceFunctional Determinants of Human Enteric -Defensin HD5: CRUCIAL ROLE FOR HYDROPHOBICITY AT DIMER INTERFACEDiscovery of defense- and neuropeptides in social ants by genome-miningStrain-specific polymorphisms in Paneth cell α-defensins of C57BL/6 mice and evidence of vestigial myeloid α-defensin pseudogenesElevated expression of Paneth cell CRS4C in ileitis-prone SAMP1/YitFc mice: regional distribution, subcellular localization, and mechanism of action.Human defensin 5 disulfide array mutants: disulfide bond deletion attenuates antibacterial activity against Staphylococcus aureusHydrophobic determinants of α-defensin bactericidal activity.Insight into the mechanisms of adenovirus capsid disassembly from studies of defensin neutralizationPaneth cell α-defensins in enteric innate immunityDelineation of interfaces on human alpha-defensins critical for human adenovirus and human papillomavirus inhibitionHuman defensins 5 and 6 enhance HIV-1 infectivity through promoting HIV attachment.Antagonist-induced conformational changes in dopamine transporter extracellular loop two involve residues in a potential salt bridgeEnteric alpha defensins in norm and pathology.Defensins Potentiate a Neutralizing Antibody Response to Enteric Viral Infection.Critical determinants of human α-defensin 5 activity against non-enveloped viruses.Total chemical synthesis of dengue 2 virus capsid protein via native chemical ligation: role of the conserved salt-bridge.Reduction of human defensin 5 affords a high-affinity zinc-chelating peptide.Electropositive charge in alpha-defensin bactericidal activity: functional effects of Lys-for-Arg substitutions vary with the peptide primary structure.α-Defensins in human innate immunity.Guardians of the Gut: Enteric Defensins.Key Determinants of Human α-Defensin 5 and 6 for Enhancement of HIV Infectivity.Salt bridge as a gatekeeper against partial unfolding.Visualizing attack of Escherichia coli by the antimicrobial peptide human defensin 5.Distinct profiling of antimicrobial peptide familiesSpotlight on Human LL-37, an Immunomodulatory Peptide with Promising Cell-Penetrating Properties.
P2860
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P2860
The conserved salt bridge in human alpha-defensin 5 is required for its precursor processing and proteolytic stability
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The conserved salt bridge in h ...... sing and proteolytic stability
@en
type
label
The conserved salt bridge in h ...... sing and proteolytic stability
@en
prefLabel
The conserved salt bridge in h ...... sing and proteolytic stability
@en
P2093
P2860
P356
P1476
The conserved salt bridge in h ...... sing and proteolytic stability
@en
P2093
Erik de Leeuw
Jacek Lubkowski
Marzena Pazgier
Mohsen Rajabi
P2860
P304
21509-21518
P356
10.1074/JBC.M801851200
P407
P577
2008-05-22T00:00:00Z