NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss.
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Tau Oligomers: The Toxic Player at Synapses in Alzheimer's DiseaseAlzheimer's disease-like APP processing in wild-type mice identifies synaptic defects as initial steps of disease progression.Tau Protein Mediates APP Intracellular Domain (AICD)-Induced Alzheimer's-Like Pathological Features in MiceTau Biology and Tau-Directed Therapies for Alzheimer's DiseaseRole of NMDA Receptor-Mediated Glutamatergic Signaling in Chronic and Acute NeuropathologiesAβ-mediated spine changes in the hippocampus are microtubule-dependent and can be reversed by a subnanomolar concentration of the microtubule-stabilizing agent epothilone DFingolimod Limits Acute Aβ Neurotoxicity and Promotes Synaptic Versus Extrasynaptic NMDA Receptor Functionality in Hippocampal NeuronsAbeta(1-42) enhances neuronal excitability in the CA1 via NR2B subunit-containing NMDA receptorsThe epigenetic dimension of Alzheimer's disease: causal, consequence, or curiosity?More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegenerationModels of β-amyloid induced Tau-pathology: the long and "folded" road to understand the mechanism.Roles of sigma-1 receptors in Alzheimer's disease.The role of the tripartite glutamatergic synapse in the pathophysiology of Alzheimer's disease.Region-specific dendritic simplification induced by Aβ, mediated by tau via dysregulation of microtubule dynamics: a mechanistic distinct event from other neurodegenerative processes.Calcium flux-independent NMDA receptor activity is required for Aβ oligomer-induced synaptic lossIncreasing the Receptor Tyrosine Kinase EphB2 Prevents Amyloid-β-induced Depletion of Cell Surface Glutamate Receptors by a Mechanism That Requires the PDZ-binding Motif of EphB2 and Neuronal Activity.Enhanced expression of NR2B subunits of NMDA receptors in the inherited glaucomatous DBA/2J mouse retina.Differential effects of synaptic and extrasynaptic NMDA receptors on Aβ-induced nitric oxide production in cerebrocortical neuronsEmerging Synaptic Molecules as Candidates in the Etiology of Neurological Disorders.The role of extracellular Tau in the spreading of neurofibrillary pathology.Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures.Reciprocal disruption of neuronal signaling and Aβ production mediated by extrasynaptic NMDA receptors: a downward spiral.Glutamate receptors function as scaffolds for the regulation of β-amyloid and cellular prion protein signaling complexes.The Functional and Molecular Properties, Physiological Functions, and Pathophysiological Roles of GluN2A in the Central Nervous System.Local Somatodendritic Translation and Hyperphosphorylation of Tau Protein Triggered by AMPA and NMDA Receptor Stimulation.Microtubule dynamics and the neurodegenerative triad of Alzheimer's disease: The hidden connection.Location- and Subunit-Specific NMDA Receptors Determine the Developmental Sevoflurane Neurotoxicity Through ERK1/2 Signaling.Signaling pathways and posttranslational modifications of tau in Alzheimer's disease: the humanization of yeast cells.Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice.Erythropoietin Restores Long-Term Neurocognitive Function Involving Mechanisms of Neuronal Plasticity in a Model of Hyperoxia-Induced Preterm Brain Injury.Synaptophysin depletion and intraneuronal Aβ in organotypic hippocampal slice cultures from huAPP transgenic mice.Non-amyloidogenic effects of α2 adrenergic agonists: implications for brimonidine-mediated neuroprotection.BDNF pro-peptide regulates dendritic spines via caspase-3.Potential involvement of GRIN2B encoding the NMDA receptor subunit NR2B in the spectrum of Alzheimer's disease.SPARCL1 Accelerates Symptom Onset in Alzheimer's Disease and Influences Brain Structure and Function During Aging.Dose-Dependent Neuroprotection and Neurotoxicity of Simvastatin through Reduction of Farnesyl Pyrophosphate in Mice Treated with Intracerebroventricular Injection of Aβ 1-42.Neural stem cell transplants improve cognitive function without altering amyloid pathology in an APP/PS1 double transgenic model of Alzheimer's disease.
P2860
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P2860
NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
NMDA receptor subunit composit ...... egeneration and synaptic loss.
@ast
NMDA receptor subunit composit ...... egeneration and synaptic loss.
@en
type
label
NMDA receptor subunit composit ...... egeneration and synaptic loss.
@ast
NMDA receptor subunit composit ...... egeneration and synaptic loss.
@en
prefLabel
NMDA receptor subunit composit ...... egeneration and synaptic loss.
@ast
NMDA receptor subunit composit ...... egeneration and synaptic loss.
@en
P2093
P2860
P356
P1476
NMDA receptor subunit composit ...... degeneration and synaptic loss
@en
P2093
R M Nitsch
S Grinschgl
U Konietzko
P2860
P356
10.1038/CDDIS.2013.129
P577
2013-04-25T00:00:00Z