Hereditary hemochromatosis: effects of C282Y and H63D mutations on association with beta2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells.
about
Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenumThe hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cellsCrystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptorHFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expressionCo-localization of the mammalian hemochromatosis gene product (HFE) and a newly identified transferrin receptor (TfR2) in intestinal tissue and cellsThe hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand bindingHRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradationN-glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin bindingCharacterization of CA XV, a new GPI-anchored form of carbonic anhydrasePathophysiology of hereditary hemochromatosisRecent advances in understanding haemochromatosis: a transition stateAssociation between hemochromatosis genotype and lead exposure among elderly men: the normative aging studyImpact of HFE genetic testing on clinical presentation of hereditary hemochromatosis: new epidemiological dataHFE H63D mutation frequency shows an increase in Turkish women with breast cancerThe delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiologyHemochromatosis gene in leukemia and lymphomaHFE gene knockout produces mouse model of hereditary hemochromatosisEffects of strain and age on hepatic gene expression profiles in murine models of HFE-associated hereditary hemochromatosisLead-related genetic loci, cumulative lead exposure and incident coronary heart disease: the Normative Aging StudyEvidence for the high importance of co-morbid factors in HFE C282Y/H63D patients cared by phlebotomies: results from an observational prospective studySerum iron levels and the risk of Parkinson disease: a Mendelian randomization study.Expression of hereditary hemochromatosis C282Y HFE protein in HEK293 cells activates specific endoplasmic reticulum stress responses.Infection with Mycobacterium avium differentially regulates the expression of iron transport protein mRNA in murine peritoneal macrophages.Hereditary haemochromatosis: diagnosis and management in the gene era.Stoichiometries of transferrin receptors 1 and 2 in human liverCharacterization of the interaction between diferric transferrin and transferrin receptor 2 by functional assays and atomic force microscopy.The haemochromatosis gene: a global perspective and implications for the Asia-Pacific region.Pathophysiological consequences and benefits of HFE mutations: 20 years of research.Human cytomegalovirus protein US2 interferes with the expression of human HFE, a nonclassical class I major histocompatibility complex molecule that regulates iron homeostasis.HFE gene variants, iron, and lipids: a novel connection in Alzheimer's diseaseRegulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis.Iron uptake from plasma transferrin by the duodenum is impaired in the Hfe knockout mouse.The ins and outs of bacterial iron metabolism.Intracellular iron transport and storage: from molecular mechanisms to health implications.Human leukocyte antigen haplotypes and HFE mutations in Spanish hereditary hemochromatosis and sporadic porphyria cutanea tarda.Physiology of iron transport and the hemochromatosis gene.Iron and immunity: a double-edged sword.Haemochromatosis: understanding the mechanism of disease and implications for diagnosis and patient management following the recent cloning of novel genes involved in iron metabolism.Molecular pathogenesis of iron overload.Contribution of the H63D mutation in HFE to murine hereditary hemochromatosis.
P2860
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P2860
Hereditary hemochromatosis: effects of C282Y and H63D mutations on association with beta2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Hereditary hemochromatosis: ef ...... he HFE protein in COS-7 cells.
@ast
Hereditary hemochromatosis: ef ...... he HFE protein in COS-7 cells.
@en
type
label
Hereditary hemochromatosis: ef ...... he HFE protein in COS-7 cells.
@ast
Hereditary hemochromatosis: ef ...... he HFE protein in COS-7 cells.
@en
prefLabel
Hereditary hemochromatosis: ef ...... he HFE protein in COS-7 cells.
@ast
Hereditary hemochromatosis: ef ...... he HFE protein in COS-7 cells.
@en
P2093
P2860
P356
P1476
Hereditary hemochromatosis: ef ...... he HFE protein in COS-7 cells.
@en
P2093
R C Schatzman
R S Britton
S Parkkila
Z Tsuchihashi
P2860
P304
12384-12389
P356
10.1073/PNAS.94.23.12384
P407
P577
1997-11-01T00:00:00Z