HFE gene knockout produces mouse model of hereditary hemochromatosis - Wikidata - wikimedia - TriplyDB

HFE gene knockout produces mouse model of hereditary hemochromatosis

HFE gene knockout produces mouse model of hereditary hemochromatosis

http://www.wikidata.org/entity/Q28263309

about

Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum The hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells Alcoholic liver disease and hepatitis C: a frequently underestimated combination Co-localization of the mammalian hemochromatosis gene product (HFE) and a newly identified transferrin receptor (TfR2) in intestinal tissue and cells Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload The WT hemochromatosis protein HFE inhibits CD8⁺ T-lymphocyte activation Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis Severe iron deficiency anemia in transgenic mice expressing liver hepcidin Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia Pathophysiology of hereditary hemochromatosis Haemochromatosis Iron overload favors the elimination of Leishmania infantum from mouse tissues through interaction with reactive oxygen and nitrogen species Experimental hemochromatosis due to MHC class I HFE deficiency: immune status and iron metabolism Increased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseases Mechanisms of divalent metal toxicity in affective disorders A mouse model of familial porphyria cutanea tarda Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis Contribution of Hfe expression in macrophages to the regulation of hepatic hepcidin levels and iron loading Ferroportin-1 is a 'nuclear'-negative acute-phase protein in rat liver: a comparison with other iron-transport proteins Hepcidin regulates ferroportin expression and intracellular iron homeostasis of erythroblasts Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: increased duodenal expression of the iron transporter DMT1 Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice Expression of hereditary hemochromatosis C282Y HFE protein in HEK293 cells activates specific endoplasmic reticulum stress responses.Global transcriptional response to Hfe deficiency and dietary iron overload in mouse liver and duodenum Hereditary haemochromatosis: diagnosis and management in the gene era.Conservation and diversification of MHC class I and its related molecules in vertebrates.Metal ion transporters in mammals: structure, function and pathological implications.Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice.Human cytomegalovirus protein US2 interferes with the expression of human HFE, a nonclassical class I major histocompatibility complex molecule that regulates iron homeostasis.Taming the elephant: Salmonella biology, pathogenesis, and prevention.Back to the fold: T cell recognition of HFE, a MHC class Ib molecule that regulates iron metabolism Expression analysis of the yersiniabactin receptor gene fyuA and the heme receptor hemR of Yersinia enterocolitica in vitro and in vivo using the reporter genes for green fluorescent protein and luciferase.Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis.Iron uptake from plasma transferrin by the duodenum is impaired in the Hfe knockout mouse.The ins and outs of bacterial iron metabolism.Intracellular iron transport and storage: from molecular mechanisms to health implications.The role of iron in the immune response to bacterial infection Pumping iron: the strange partnership of the hemochromatosis protein, a class I MHC homolog, with the transferrin receptor.Hepcidin: a putative iron-regulatory hormone relevant to hereditary hemochromatosis and the anemia of chronic disease.Hfe deficiency impairs pulmonary neutrophil recruitment in response to inflammation.

P2860

Q22001443-99009BD8-0E39-4845-AE3E-AC2EAC4B20B1 Q22009072-F9F1E76A-AE7C-430A-B7A8-D0146224AFF3 Q22305502-AC356169-5016-496E-AC62-9A7A4FD7047B Q24300212-A8806324-C534-4D5B-AED8-3A73D594E4DF Q24312272-A3C649AF-4E47-42BE-9339-E368EF512D11 Q24339411-7A7AA7B3-09E1-4C18-A729-B315DA991E21 Q24533580-B4ADDFF1-D8D1-4EE7-AA28-D187FA436727 Q24536163-2A561526-B269-474C-9AF3-4368DD03DB74 Q24555135-9483C261-C7A6-45A1-8CAB-202C827AC1FF Q24654441-D3957032-9560-41A9-92FB-D81D149A049C Q24685891-E4D62FC9-E10A-4238-96FF-B8FD1A01B818 Q27305261-0B379F41-89FA-4E63-93C4-F34778D703AC Q28137777-5DEBDB1F-5633-42EA-8D6C-4D318D64A18E Q28344887-95A51E70-1BA5-42C4-B55C-08DE1DD1B298 Q28384836-622954AC-5F40-4520-8C60-7614BE7B1183 Q28507743-66106218-EACE-4A2D-BB42-44669547E74F Q28508392-37704129-1C20-4A62-A956-6CA1EC60D45B Q28512327-BE473418-50B1-4CED-880E-8B0D4D5D6FE8 Q28578052-4DC3996C-8F06-4B00-8DC7-5712F5BB9E03 Q28585215-0388F917-0223-4317-BD51-6B9BCB64675D Q28585417-745D4F9B-8C93-4602-8877-FE09006EF50A Q28586797-1F3DB07D-D8B3-42EE-90DA-45385C208F81 Q33291582-11049250-8FBC-4F9C-837F-B7CAF6C966B0 Q33507280-046DD892-E29F-4E40-8C7E-1645F5796AE1 Q33603907-EC9C6F10-6FF3-4033-A64D-27C67FB082E4 Q33630631-67E57457-146A-4BF0-B102-9D44A2E3653C Q33663264-998AB0F8-A23C-46F7-9A84-55DC5073F832 Q33806074-CC49AEEC-9EF6-4E27-B751-05D76A6B1442 Q33848523-46F4FC1A-90D9-45FB-B86F-FD13CCEC2EE4 Q33877264-286E6F1E-DDE0-415C-9ABF-A0E8E367EB3A Q33943959-66FB6D70-ABCD-4080-8684-AD97FE264CE5 Q34009866-EA31A957-245F-44C4-A369-8D7A293117C5 Q34016565-11EF628B-AFAE-4BB6-9DEB-F5421F380BE3 Q34025772-7D7108B4-13AD-4BCB-82E2-59A0E91B85F2 Q34055559-C2F508F2-ACB5-4762-B1C3-AA6729537223 Q34100135-8F869E39-8D73-4A13-A851-90F88D83709A Q34155194-5618B639-2E7F-4384-A1E0-A3E87BF949A8 Q34190689-A6AE022A-EF84-4193-BE84-71A3A413E51F Q34311597-67925B5C-B67E-48F1-9BDC-1DC70DA3649F Q34321351-CDDF573C-37D1-47A0-8A36-4F7311AEAC86

P2860

HFE gene knockout produces mouse model of hereditary hemochromatosis

http://www.wikidata.org/entity/Q28263309

description

1998 nî lūn-bûn

@nan

1998 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի մարտին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年学术文章

@wuu

1998年学术文章

@zh-cn

1998年学术文章

@zh-hans

1998年学术文章

@zh-my

1998年学术文章

@zh-sg

1998年學術文章

@yue

name

HFE gene knockout produces mouse model of hereditary hemochromatosis

@ast

HFE gene knockout produces mouse model of hereditary hemochromatosis

@en

HFE gene knockout produces mouse model of hereditary hemochromatosis

@nl

type

label

HFE gene knockout produces mouse model of hereditary hemochromatosis

@ast

HFE gene knockout produces mouse model of hereditary hemochromatosis

@en

HFE gene knockout produces mouse model of hereditary hemochromatosis

@nl

prefLabel

HFE gene knockout produces mouse model of hereditary hemochromatosis

@ast

HFE gene knockout produces mouse model of hereditary hemochromatosis

@en

HFE gene knockout produces mouse model of hereditary hemochromatosis

@nl

P1433

Q28263309-0E1E0FBE-E2F4-43AE-938B-31B22D76E3E4

P1476

Q28263309-644E30A4-3E3E-42C7-840E-0F5D8F8B4315

P2093

Q28263309-0330ECA2-8141-4EBB-B7F6-4095E6C8C334

Q28263309-3AC355B5-54FE-4871-B4D9-6720E939E194

Q28263309-3E6E1E17-01EE-4E1D-A6EC-34E91A33D52F

Q28263309-4ADEB793-DF6B-413A-AC93-9F550FE99827

Q28263309-4B5F9B26-1427-4F66-BFFE-C5AAADC3586C

Q28263309-525F1CCF-FAB1-4388-A59C-5D056C61BA7C

Q28263309-A4E7E243-7F04-4791-81FA-61C6272BAEF4

Q28263309-C7FBF023-727E-4A82-A359-C5A7A9A1F3EA

Q28263309-CCBD56B4-D72E-4F02-9BD1-7D7251B57E1E

Q28263309-D6DE9995-0296-4C50-9C9C-A8036DD5FECA

P2860

Q28263309-0335C32D-869C-43A1-9724-CF8B330D423D

Q28263309-036E6C3B-E74E-4375-8079-6B099C91FAED

Q28263309-0514480A-8186-463F-9EF9-6C8757971005

Q28263309-07353FCD-7088-4EE1-82AC-21A00BC9C114

Q28263309-22626F4A-7D58-4805-8759-20BAB963F4CA

Q28263309-3B36DEB7-B578-4536-A775-21AD40A54C3E

Q28263309-578552C4-CECA-4DDE-9B9B-301A7B108F70

Q28263309-65D3094B-9BD6-44F9-ACA5-D7F914F80176

Q28263309-7CD95F2E-F8F0-4C58-A686-EBFA2CCEB25F

Q28263309-85DF7B45-AAB9-45F9-B1BE-4BC562CA583D

P304

Q28263309-AFC830B0-0F42-44CC-958D-2C1946E9EF75

P31

Q28263309-85EB44D3-247D-4B2D-9368-71A88A3C7F53

P3181

Q28263309-7051733A-F8F1-4DA1-8613-9910334B8D38

P356

Q28263309-73CFC791-7F63-4D55-AAEB-B1D98A2EC4F7

P407

Q28263309-BB33D2B0-2AEC-466A-81FF-3516083DC5A7

P433

Q28263309-AD6E5EA9-768E-4D6F-940D-02E08614F535

P478

Q28263309-3ADB35A2-A0FE-4AAF-8955-7DAF402914B7

P50

Q28263309-79042D08-154D-4034-AA1C-C9EE2FF966C3

P577

Q28263309-8CF2537F-8886-4EB7-9C81-57E2BA948A8D

P5875

Q28263309-CF8BC1C3-714E-4305-8AC6-18037DCB6414

P698

Q28263309-B9029B97-1F8B-4835-81CE-C70DF3FC83A1

P932

Q28263309-9F22C647-E8A7-4762-A545-93D8F1BE8240

P3181

P356

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

HFE gene knockout produces mouse model of hereditary hemochromatosis

@en

P2093

A Waheed

http://www.w3.org/2001/XMLSchema#string

B R Bacon

http://www.w3.org/2001/XMLSchema#string

C E Prass

http://www.w3.org/2001/XMLSchema#string

D A Ruddy

http://www.w3.org/2001/XMLSchema#string

E M Brunt

http://www.w3.org/2001/XMLSchema#string

J Jiang

http://www.w3.org/2001/XMLSchema#string

R C Schatzman

http://www.w3.org/2001/XMLSchema#string

R E Fleming

http://www.w3.org/2001/XMLSchema#string

R O'Neill

http://www.w3.org/2001/XMLSchema#string

R S Britton

http://www.w3.org/2001/XMLSchema#string

P2860

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

The hemochromatosis founder mutation in HLA-H disrupts beta2-microglobulin interaction and cell surface expression

Association of the transferrin receptor in human placenta with HFE, the protein defective in hereditary hemochromatosis

A mouse model for beta 0-thalassemia

Tissue distribution and clearance kinetics of non-transferrin-bound iron in the hypotransferrinemic mouse: a rodent model for hemochromatosis.

Mutation analysis of the HLA-H gene in Italian hemochromatosis patients

Immunohistochemistry of HLA-H, the protein defective in patients with hereditary hemochromatosis, reveals unique pattern of expression in gastrointestinal tract.

Defective iron homeostasis in beta 2-microglobulin knockout mice recapitulates hereditary hemochromatosis in man.

Heme oxygenase 1 is required for mammalian iron reutilization

Hereditary hemochromatosis: effects of C282Y and H63D mutations on association with beta2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells.

P304

2492-2497

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

523646

http://www.w3.org/2001/XMLSchema#string

P356

10.1073/PNAS.95.5.2492

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

95

http://www.w3.org/2001/XMLSchema#string

P50

P577

1998-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

13748555

http://www.w3.org/2001/XMLSchema#string

P698

9482913

http://www.w3.org/2001/XMLSchema#string

P932

19387

http://www.w3.org/2001/XMLSchema#string