Four viral genes independently contribute to attenuation of live influenza A/Ann Arbor/6/60 (H2N2) cold-adapted reassortant virus vaccines.
about
Emergence of influenza A virusesPolygenic control of neuroinvasiveness in California serogroup bunyavirusesReverse Genetics Approaches for the Development of Influenza VaccinesNew aspects of influenza viruses.Specific residues of PB2 and PA influenza virus polymerase subunits confer the ability for RNA polymerase II degradation and virus pathogenicity in miceReversion of Cold-Adapted Live Attenuated Influenza Vaccine into a Pathogenic VirusEngineering temperature sensitive live attenuated influenza vaccines from emerging viruses.Influenza HA subtypes demonstrate divergent phenotypes for cleavage activation and pH of fusion: implications for host range and adaptationIdentification of mutations contributing to the temperature-sensitive, cold-adapted, and attenuation phenotypes of the live-attenuated cold-passage 45 (cp45) human parainfluenza virus 3 candidate vaccine.Recombinant respiratory syncytial virus bearing a deletion of either the NS2 or SH gene is attenuated in chimpanzees.Attenuating mutations of the matrix gene of influenza A/WSN/33 virus.Development of an Alternative Modified Live Influenza B Virus Vaccine.Three amino acid substitutions in the L protein of the human parainfluenza virus type 3 cp45 live attenuated vaccine candidate contribute to its temperature-sensitive and attenuation phenotypesRecombinant respiratory syncytial virus (RSV) bearing a set of mutations from cold-passaged RSV is attenuated in chimpanzeesMolecular correlates of influenza A H5N1 virus pathogenesis in mice.Comparison of predicted amino acid sequences of measles virus strains in the Edmonston vaccine lineage.Genotypic stability of cold-adapted influenza virus vaccine in an efficacy clinical trial.Live attenuated influenza vaccine, trivalent, is safe in healthy children 18 months to 4 years, 5 to 9 years, and 10 to 18 years of age in a community-based, nonrandomized, open-label trial.Emerging respiratory viruses: challenges and vaccine strategiesDevelopment of a mouse-adapted live attenuated influenza virus that permits in vivo analysis of enhancements to the safety of live attenuated influenza virus vaccine.Multiple genome segments determine virulence of bluetongue virus serotype 8Palmitylation of the influenza virus hemagglutinin (H3) is not essential for virus assembly or infectivityGenetically engineered live attenuated influenza A virus vaccine candidatesRestricted replication of the live attenuated influenza A virus vaccine during infection of primary differentiated human nasal epithelial cellsMutations Designed by Ensemble Defect to Misfold Conserved RNA Structures of Influenza A Segments 7 and 8 Affect Splicing and Attenuate Viral Replication in Cell CultureMolecular and biological changes in the cold-adapted "master strain" A/AA/6/60 (H2N2) influenza virus.Primary pulmonary cytotoxic T lymphocytes induced by immunization with a vaccinia virus recombinant expressing influenza A virus nucleoprotein peptide do not protect mice against challengeEvaluation of the genetic stability of the temperature-sensitive PB2 gene mutation of the influenza A/Ann Arbor/6/60 cold-adapted vaccine virus.Rescue of an influenza A virus wild-type PB2 gene and a mutant derivative bearing a site-specific temperature-sensitive and attenuating mutation.Intragenic suppression of a deletion mutation of the nonstructural gene of an influenza A virusNeuroattenuation of an avirulent bunyavirus variant maps to the L RNA segment.Passively transferred monoclonal antibody to the M2 protein inhibits influenza A virus replication in mice.Rearrangement of Influenza Virus Spliced Segments for the Development of Live-Attenuated Vaccines.Effect of simultaneous administration of cold-adapted and wild-type influenza A viruses on experimental wild-type influenza infection in humansGeneration and protective efficacy of a cold-adapted attenuated avian H9N2 influenza vaccine.Systemic and local antibody responses in elderly subjects given live or inactivated influenza A virus vaccinesEnhancement of anti-influenza A virus cytotoxicity following influenza A virus vaccination in older, chronically ill adults.Attenuated strains of influenza A viruses do not induce degradation of RNA polymerase II.An influenza A virus containing influenza B virus 5' and 3' noncoding regions on the neuraminidase gene is attenuated in mice.Development of live-attenuated arenavirus vaccines based on codon deoptimization of the viral glycoprotein.
P2860
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P2860
Four viral genes independently contribute to attenuation of live influenza A/Ann Arbor/6/60 (H2N2) cold-adapted reassortant virus vaccines.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Four viral genes independently ...... ed reassortant virus vaccines.
@en
type
label
Four viral genes independently ...... ed reassortant virus vaccines.
@en
prefLabel
Four viral genes independently ...... ed reassortant virus vaccines.
@en
P2093
P2860
P1433
P1476
Four viral genes independently ...... ed reassortant virus vaccines.
@en
P2093
B R Murphy
D Herrington
E L Tierney
H F Maassab
M H Snyder
M L Clements
P2860
P304
P407
P577
1988-02-01T00:00:00Z