Disruption of epithelial architecture caused by loss of PTEN or by oncogenic mutant p110α/PIK3CA but not by HER2 or mutant AKT1.
about
Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110αPTEN induces apoptosis and cavitation via HIF-2-dependent Bnip3 upregulation during epithelial lumen formationInfluence maximization in time bounded network identifies transcription factors regulating perturbed pathwaysPTEN is required to maintain luminal epithelial homeostasis and integrity in the adult mammary glandZinc transporter 2 interacts with vacuolar ATPase and is required for polarization, vesicle acidification, and secretion in mammary epithelial cells.Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystine-glutamate antiporter xCT.The phosphatase PTPL1 is required for PTEN-mediated regulation of apical membrane size.
P2860
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P2860
Disruption of epithelial architecture caused by loss of PTEN or by oncogenic mutant p110α/PIK3CA but not by HER2 or mutant AKT1.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Disruption of epithelial archi ...... ut not by HER2 or mutant AKT1.
@en
type
label
Disruption of epithelial archi ...... ut not by HER2 or mutant AKT1.
@en
prefLabel
Disruption of epithelial archi ...... ut not by HER2 or mutant AKT1.
@en
P2093
P2860
P356
P1433
P1476
Disruption of epithelial archi ...... ut not by HER2 or mutant AKT1.
@en
P2093
B J Eickholt
F M Berglund
L Davidson
N R Leslie
N R Weerasinghe
P2860
P2888
P304
P356
10.1038/ONC.2012.459
P407
P577
2012-10-22T00:00:00Z
P6179
1038554938