Regulated and constitutive activity by CDC25Mm (GRF), a Ras-specific exchange factor
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N terminus of Sos1 Ras exchange factor: critical roles for the Dbl and pleckstrin homology domainsRas-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of RafImprinted Rasgrf1 expression in neonatal mice affects olfactory learning and memoryCRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cellsRasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responsesGuanine nucleotide exchange factors: activators of the Ras superfamily of proteinsPhosphorylation of the Ras-GRF1 exchange factor at Ser916/898 reveals activation of Ras signaling in the cerebral cortexp75-Ras-GRF1 is a c-Jun/AP-1 target protein: its up regulation results in increased Ras activity and is necessary for c-Jun-induced nonadherent growth of Rat1a cellsVav: function and regulation in hematopoietic cell signaling.Regulation of RasGRP via a phorbol ester-responsive C1 domain.The Ras-GRF1 exchange factor coordinates activation of H-Ras and Rac1 to control neuronal morphology.Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity.The Ras-specific exchange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic RasRegulation of ras exchange factors and cellular localization of ras activation by lipid messengers in T cells.GRFbeta, a novel regulator of calcium signaling, is expressed in pancreatic beta cells and brain.Ras and Rho GTPases on the move: The RasGRF connection.Filamin A-mediated down-regulation of the exchange factor Ras-GRF1 correlates with decreased matrix metalloproteinase-9 expression in human melanoma cells.Ras-GRF activates Ha-Ras, but not N-Ras or K-Ras 4B, protein in vivo.Characterization of Ral GDP dissociation stimulator-like (RGL) activities to regulate c-fos promoter and the GDP/GTP exchange of Ral.Activation of R-Ras by Ras-guanine nucleotide-releasing factor.The Rho family GTPase Cdc42 regulates the activation of Ras/MAP kinase by the exchange factor Ras-GRF.Phosphorylation of serine 916 of Ras-GRF1 contributes to the activation of exchange factor activity by muscarinic receptors.Ras-guanine-nucleotide-releasing factors 1 and 2 interact with PLCγ at focal adhesions to enable IL-1-induced Ca(2+) signalling, ERK activation and MMP-3 expression.Phospholipase activity of phospholipase C-gamma1 is required for nerve growth factor-regulated MAP kinase signaling cascade in PC12 cells.Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS-M.Amplification of B cell receptor-Erk signaling by Rasgrf-1 overexpression in chronic lymphocytic leukemia.The N-terminal moiety of CDC25(Mm), a GDP/GTP exchange factor of Ras proteins, controls the activity of the catalytic domain. Modulation by calmodulin and calpain.
P2860
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P2860
Regulated and constitutive activity by CDC25Mm (GRF), a Ras-specific exchange factor
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Regulated and constitutive activity by CDC25Mm (GRF), a Ras-specific exchange factor
@en
type
label
Regulated and constitutive activity by CDC25Mm (GRF), a Ras-specific exchange factor
@en
prefLabel
Regulated and constitutive activity by CDC25Mm (GRF), a Ras-specific exchange factor
@en
P2093
P2860
P356
P1476
Regulated and constitutive activity by CDC25Mm (GRF), a Ras-specific exchange factor
@en
P2093
P2860
P304
P356
10.1128/MCB.13.12.7718
P407
P577
1993-12-01T00:00:00Z