Neurosteroids: deficient cognitive performance in aged rats depends on low pregnenolone sulfate levels in the hippocampus.
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Pregnenolone rescues schizophrenia-like behavior in dopamine transporter knockout mice.Local amplification of glucocorticoids in the aging brain and impaired spatial memoryDehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) as neuroactive neurosteroidsNeurosteroids: endogenous role in the human brain and therapeutic potentialsThe neurosteroid allopregnanolone increases dopamine release and dopaminergic response to morphine in the rat nucleus accumbensProof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophreniaLigand for translocator protein reverses pathology in a mouse model of Alzheimer's diseasePregnenolone sulfate block of GABA(A) receptors: mechanism and involvement of a residue in the M2 region of the alpha subunitDiminished allopregnanolone enhancement of GABA(A) receptor currents in a rat model of chronic temporal lobe epilepsyNeuroactive Steroids are Altered in Schizophrenia and Bipolar Disorder: Relevance to Pathophysiology and TherapeuticsThe Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is a Potent Allosteric Modulator of N-Methyl-D-Aspartate ReceptorsAntipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotectionCharacterization of the convulsant action of pregnenolone sulfateA comparison of three NMDA receptor antagonists in the treatment of prolonged status epilepticus.GABA(A) receptors and their associated proteins: implications in the etiology and treatment of schizophrenia and related disorders.Pregnenolone sulfate potentiates the inwardly rectifying K channel Kir2.3.Complementary and alternative medicines for Alzheimer's disease.Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesisMechanism of estradiol-induced block of voltage-gated K+ currents in rat medial preoptic neurons.The synthetic enantiomer of pregnenolone sulfate is very active on memory in rats and mice, even more so than its physiological neurosteroid counterpart: distinct mechanisms?Anti-inflammatory effects of progesterone in lipopolysaccharide-stimulated BV-2 microgliaMultiple roles for the first transmembrane domain of GABAA receptor subunits in neurosteroid modulation and spontaneous channel activity.A role for picomolar concentrations of pregnenolone sulfate in synaptic activity-dependent Ca2+ signaling and CREB activationThe NMDA receptor as a target for cognitive enhancementA steroid modulatory domain on NR2B controls N-methyl-D-aspartate receptor proton sensitivityDueling enigmas: neurosteroids and sigma receptors in the limelight.Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids.Residues in the first transmembrane domain of the Caenorhabditis elegans GABA(A) receptor confer sensitivity to the neurosteroid pregnenolone sulfate.Progesterone signaling mechanisms in brain and behavior.Regulation of neurosteroid biosynthesis by neurotransmitters and neuropeptides.Oxidative Stress-Mediated Brain Dehydroepiandrosterone (DHEA) Formation in Alzheimer's Disease DiagnosisModulation by pregnenolone sulfate of filtering properties in the hippocampal trisynaptic circuit.Role of cytochrome p450 in synaptocrinology: endogenous estrogen synthesis in the brain hippocampus.Progestin receptor subtypes in the brain: the known and the unknownLocal production of sex hormones and their modulation of hippocampal synaptic plasticity.Sigma receptors [σRs]: biology in normal and diseased statesent-Steroids: novel tools for studies of signaling pathways.Analysis of pregnenolone and dehydroepiandrosterone in rodent brain: cholesterol autoxidation is the key.Pregnanolone Glutamate, a Novel Use-Dependent NMDA Receptor Inhibitor, Exerts Antidepressant-Like Properties in Animal Models.The Singapore flagship programme in translational and clinical research in psychosis.
P2860
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P2860
Neurosteroids: deficient cognitive performance in aged rats depends on low pregnenolone sulfate levels in the hippocampus.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Neurosteroids: deficient cogni ...... ate levels in the hippocampus.
@en
type
label
Neurosteroids: deficient cogni ...... ate levels in the hippocampus.
@en
prefLabel
Neurosteroids: deficient cogni ...... ate levels in the hippocampus.
@en
P2093
P2860
P356
P1476
Neurosteroids: deficient cogni ...... ate levels in the hippocampus.
@en
P2093
C Corpéchot
E E Baulieu
M Darnaudéry
P2860
P304
14865-14870
P356
10.1073/PNAS.94.26.14865
P407
P577
1997-12-01T00:00:00Z