Human globin gene promoter sequences are sufficient for specific expression of a hybrid gene transfected into tissue culture cells
about
Positive selection of DNA-protein interactions in mammalian cells through phenotypic coupling with retrovirus production.Expression of human alpha-globin and mouse/human hybrid beta-globin genes in murine hemopoietic stem cells transduced by recombinant retroviruses.Conservation of the primary structure, organization, and function of the human and mouse beta-globin locus-activating regions.An erythroid-specific, developmental-stage-independent enhancer far upstream of the human "beta-like globin" genes.Identification of a stage selector element in the human gamma-globin gene promoter that fosters preferential interaction with the 5' HS2 enhancer when in competition with the beta-promoter.Identification and characterization of mechanistically distinct inducers of gamma-globin transcriptionFunctional profile of the human fetal gamma-globin gene upstream promoter region.Activation of the human beta-globin promoter in K562 cells by DNA sequences 5' to the fetal gamma- or embryonic zeta-globin genes.Basal expression of the histone H5 gene is controlled by positive and negative cis-acting sequences.Erythroid specific activation of the Xenopus laevis adult alpha-globin promoter in transient heterokaryons.Changes in minor transcripts from the alpha 1 and beta maj globin and glutathione peroxidase genes during erythropoiesisMethylation-enhanced binding of Sp1 to the stage selector element of the human gamma-globin gene promoter may regulate development specificity of expression.Cell type-specific protein-DNA interactions in the human zeta-globin upstream promoter region: displacement of Sp1 by the erythroid cell-specific factor NF-E1.Functional analysis of elements affecting expression of the beta-actin gene of carp.DNA sequences involved in transcriptional regulation of the mouse beta-globin promoter in murine erythroleukemia cells.Upstream G gamma-globin and downstream beta-globin sequences required for stage-specific expression in transgenic mice.Inducibility of the HS II enhancer depends on binding of an erythroid specific nuclear protein.A naturally occurring gamma globin gene mutation enhances SP1 binding activity.Function of transfected globin promoters and the globin locus activator in K562 erythroleukemia cells.The molecular genetics of hemoglobin.Exploring strategies for the design of artificial transcription factors: targeting sites proximal to known regulatory regions for the induction of gamma-globin expression and the treatment of sickle cell disease.An erythroid specific nuclear factor binding to the proximal CACCC box of the beta-globin gene promoter.The rat albumin gene promoter is appropriately regulated in transient but not in stable transfections.Transcriptional promiscuity of the human alpha-globin gene.
P2860
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P2860
Human globin gene promoter sequences are sufficient for specific expression of a hybrid gene transfected into tissue culture cells
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
Human globin gene promoter seq ...... cted into tissue culture cells
@en
type
label
Human globin gene promoter seq ...... cted into tissue culture cells
@en
prefLabel
Human globin gene promoter seq ...... cted into tissue culture cells
@en
P2860
P356
P1476
Human globin gene promoter seq ...... cted into tissue culture cells
@en
P2093
Nienhuis AW
Rutherford T
P2860
P304
P356
10.1128/MCB.7.1.398
P407
P577
1987-01-01T00:00:00Z