Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase ε.
about
The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conservedRibonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repairStructure-function analysis of ribonucleotide bypass by B family DNA replicasesDefects in purine nucleotide metabolism lead to substantial incorporation of xanthine and hypoxanthine into DNA and RNARedundancy in ribonucleotide excision repair: Competition, compensation, and cooperationGenetic instability in budding and fission yeast-sources and mechanismsMechanisms employed by Escherichia coli to prevent ribonucleotide incorporation into genomic DNA by Pol VRibonucleotides are signals for mismatch repair of leading-strand replication errorsProcessing ribonucleotides incorporated during eukaryotic DNA replication.Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase IHow the misincorporation of ribonucleotides into genomic DNA can be both harmful and helpful to cellsMismatch repair balances leading and lagging strand DNA replication fidelity.Reduction of hRNase H2 activity in Aicardi-Goutières syndrome cells leads to replication stress and genome instabilityTracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation.Molecular biology. A new twist for topoisomerase.Balancing eukaryotic replication asymmetry with replication fidelity.RNase H and postreplication repair protect cells from ribonucleotides incorporated in DNAProofreading of ribonucleotides inserted into DNA by yeast DNA polymerase ɛTopoisomerase 1-dependent deletions initiated by incision at ribonucleotides are biased to the non-transcribed strand of a highly activated reporter.Stimulation of Chromosomal Rearrangements by Ribonucleotides.RNase H2-initiated ribonucleotide excision repair.Human DNA polymerase ε is able to efficiently extend from multiple consecutive ribonucleotides.Transcriptional responses to loss of RNase H2 in Saccharomyces cerevisiae.Ribonucleotide incorporation, proofreading and bypass by human DNA polymerase δTopoisomerase 1-mediated removal of ribonucleotides from nascent leading-strand DNAEvidence that processing of ribonucleotides in DNA by topoisomerase 1 is leading-strand specific.Differential roles of the RNases H in preventing chromosome instability.Deoxyribonucleotides as genetic and metabolic regulatorsKinetic mechanisms governing stable ribonucleotide incorporation in individual DNA polymerase complexes.Ribonucleotides and Transcription-Associated Mutagenesis in Yeast.Two distinct mechanisms of Topoisomerase 1-dependent mutagenesis in yeastStructural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu.Genome-wide mapping of embedded ribonucleotides and other noncanonical nucleotides using emRiboSeq and EndoSeq.Polynucleotide phosphorylase plays an important role in the generation of spontaneous mutations in Escherichia coli.Topoisomerase I-mediated cleavage at unrepaired ribonucleotides generates DNA double-strand breaks.Studying Topoisomerase 1-Mediated Damage at Genomic Ribonucleotides.Topoisomerase I and Genome Stability: The Good and the Bad.The role of RNase H2 in processing ribonucleotides incorporated during DNA replication.Mispaired rNMPs in DNA are mutagenic and are targets of mismatch repair and RNases H.Muver, a computational framework for accurately calling accumulated mutations.
P2860
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P2860
Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase ε.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Mismatch repair-independent ta ...... rporation by DNA polymerase ε.
@en
type
label
Mismatch repair-independent ta ...... rporation by DNA polymerase ε.
@en
prefLabel
Mismatch repair-independent ta ...... rporation by DNA polymerase ε.
@en
P2860
P1433
P1476
Mismatch repair-independent ta ...... orporation by DNA polymerase ε
@en
P2093
Alan B Clark
Grace E Kissling
P2860
P304
P356
10.1016/J.DNAREP.2011.02.001
P577
2011-03-16T00:00:00Z