Discovery of activation-induced cytidine deaminase, the engraver of antibody memory.
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Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutationMicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocationRelated Mechanisms of Antibody Somatic Hypermutation and Class Switch RecombinationMechanism of somatic hypermutation at the WA motif by human DNA polymerase η.AID targeting: old mysteries and new challengesADAR1 protein induces adenosine-targeted DNA mutations in senescent Bcl6 gene-deficient cellsFurther evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination.AID in aging and autoimmune diseases.Effects of age on H1N1-specific serum IgG1 and IgG3 levels evaluated during the 2011-2012 influenza vaccine seasonImpact of phosphorylation and phosphorylation-null mutants on the activity and deamination specificity of activation-induced cytidine deaminase.Patterns of receptor revision in the immunoglobulin heavy chains of a teleost fishMechanisms of chromosomal rearrangement in the human genomeThe endogenous exposome.Widespread genomic breaks generated by activation-induced cytidine deaminase are prevented by homologous recombination.Regulation of the IgE response.Opinion: uracil DNA glycosylase (UNG) plays distinct and non-canonical roles in somatic hypermutation and class switch recombination.LINE-1 retroelements complexed and inhibited by activation induced cytidine deaminase.Innate signaling networks in mucosal IgA class switchingAPE1 is dispensable for S-region cleavage but required for its repair in class switch recombination.The regulation of IgA class switching.The AID-induced DNA damage response in chromatin.Uracil DNA glycosylase counteracts APOBEC3G-induced hypermutation of hepatitis B viral genomes: excision repair of covalently closed circular DNA.B cell function and influenza vaccine responses in healthy aging and disease.Intrinsic defects in B cell response to seasonal influenza vaccination in elderly humans.Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminaseTGF-β suppression of HBV RNA through AID-dependent recruitment of an RNA exosome complex.Aging impairs murine B cell differentiation and function in primary and secondary lymphoid tissuesRNA editing of hepatitis B virus transcripts by activation-induced cytidine deaminaseGerminal center B cells govern their own fate via antibody feedback.Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes.Dissociation of in vitro DNA deamination activity and physiological functions of AID mutants.Carboxy-terminal domain of AID required for its mRNA complex formation in vivo.G clustering is important for the initiation of transcription-induced R-loops in vitro, whereas high G density without clustering is sufficient thereafterIkaros controls isotype selection during immunoglobulin class switch recombination.Dealing with dangerous accidents: DNA double-strand breaks take centre stage. Symposium on Genome Instability and DNA Repair.Molecular mechanism for generation of antibody memory.A portable hot spot recognition loop transfers sequence preferences from APOBEC family members to activation-induced cytidine deaminase.Effects of aging on B cell function.Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylaseMolecular insights into systemic lupus erythematosus pathogenesis
P2860
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P2860
Discovery of activation-induced cytidine deaminase, the engraver of antibody memory.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Discovery of activation-induced cytidine deaminase, the engraver of antibody memory.
@en
type
label
Discovery of activation-induced cytidine deaminase, the engraver of antibody memory.
@en
prefLabel
Discovery of activation-induced cytidine deaminase, the engraver of antibody memory.
@en
P2093
P1476
Discovery of activation-induced cytidine deaminase, the engraver of antibody memory.
@en
P2093
Hitoshi Nagaoka
Nasim A Begum
Reiko Shinkura
P356
10.1016/S0065-2776(06)94001-2
P577
2007-01-01T00:00:00Z