A possible role for cathepsins D, E, and B in the processing of beta-amyloid precursor protein in Alzheimer's disease.
about
Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's diseaseHuman stefin B role in cell's response to misfolded proteins and autophagyHuman brain carboxypeptidase B, which cleaves beta-amyloid peptides in vitro, is expressed in the endoplasmic reticulum of neurons.Microglial secreted cathepsin B induces neuronal apoptosis.Comparative proteomics of cerebrospinal fluid in neuropathologically-confirmed Alzheimer's disease and non-demented elderly subjects.Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation.Physiological Functions of the β-Site Amyloid Precursor Protein Cleaving Enzyme 1 and 2Selective detection of Cathepsin E proteolytic activity.The functions of the amyloid precursor protein gene.Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficitsEndocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations.The endocytic pathway in microglia during health, aging and Alzheimer's disease.ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease.Protein truncation as a common denominator of human neurodegenerative foldopathies.Molecular modeling approach to explore the role of cathepsin B from Hordeum vulgare in the degradation of Aβ peptides.Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis.Aβ42-mediated proteasome inhibition and associated tau pathology in hippocampus are governed by a lysosomal response involving cathepsin B: Evidence for protective crosstalk between protein clearance pathways.Novel cathepsin D inhibitors block the formation of hyperphosphorylated tau fragments in hippocampus.An active zymogen: unravelling the mystery of tissue-type plasminogen activator.Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cellsInteraction of human breast fibroblasts with collagen I increases secretion of procathepsin B.The Multifaceted Role of the Lysosomal Protease Cathepsins in Kidney Disease.A mechanistic model to predict effects of cathepsin B and cystatin C on β-amyloid aggregation and degradation.A novel approach for characterization of cathepsin D protease and its effect on tau and β-amyloid proteins.
P2860
Q24324577-FB4178EF-2EE0-4FCB-8700-78B40E6F2A38Q28540970-1C8912DD-16E8-4888-96F6-BF067B9B6E47Q30669863-2D2BC1E6-C95E-490A-B316-0019FC38BE96Q32134547-34655622-7F4D-420D-83D0-2C166CCA294AQ33237201-D3B1FA10-E329-4F05-8DE5-0B28CB3627B4Q33293158-9C22927C-CAF2-472E-95F5-9E0168EFDF0BQ33575863-5A4A5160-E349-4795-8861-DAD58424ACCFQ34039858-60249AC5-4943-463C-B73A-CEA3D82327F7Q34173160-9674FD13-2A04-462C-81C8-05C53C07C59AQ34438646-C4FCB7F1-C533-486F-AD94-2FF9E5CCC076Q35745983-AD76370A-FD68-4EE6-86B1-EEF6DD9B910BQ36078890-AF0CC555-ED86-41A4-8CE6-AF4FEC4BA157Q37149914-C979F267-96CE-489A-9560-1614F35426DFQ38091670-FC0C8AA5-B4DE-4F21-93A3-E634647D2F25Q40321150-13B3FA7B-9709-4F93-A8F1-05FB70A6A12BQ40781162-FD955598-D0B9-497A-B08B-6DBBDC137D2DQ41348866-EC14E38B-3BDC-4406-99C0-89435530BCE6Q41727024-81D7960E-DC98-4D37-B2C8-9E3ED50AD4C3Q41730397-0884C5C6-2163-4D87-947D-989DF0633679Q42102273-8FF2FDBB-3439-4DC6-A7CD-7AA23F05FD9FQ44033510-5DF3A069-894C-44B4-941F-AE9AF7EFF294Q47171560-FEB61463-24BB-4222-AC8B-BAFE2C378445Q47432033-4BBB17AF-91E9-411B-8063-60D47E4859D6Q50313086-9EADD691-59FC-4BE3-B7A8-1AB182A4C30A
P2860
A possible role for cathepsins D, E, and B in the processing of beta-amyloid precursor protein in Alzheimer's disease.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
A possible role for cathepsins ...... rotein in Alzheimer's disease.
@en
type
label
A possible role for cathepsins ...... rotein in Alzheimer's disease.
@en
prefLabel
A possible role for cathepsins ...... rotein in Alzheimer's disease.
@en
P2093
P2860
P1433
P1476
A possible role for cathepsins ...... protein in Alzheimer's disease
@en
P2093
A Van Dorsselaer
B Heintzelmann
E A Mackay
P2860
P304
P356
10.1111/J.1432-1033.1997.00414.X
P407
P577
1997-03-01T00:00:00Z