A drosophila model for amyotrophic lateral sclerosis reveals motor neuron damage by human SOD1.
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Characterization of the properties of a novel mutation in VAPB in familial amyotrophic lateral sclerosisFrom animal models to human disease: a genetic approach for personalized medicine in ALSDrosophila tools and assays for the study of human diseasesAxonal transport disruption in peripheral nerve disease: From Jack's discoveries as a resident to recent contributionsAn ALS-linked mutant SOD1 produces a locomotor defect associated with aggregation and synaptic dysfunction when expressed in neurons of Caenorhabditis elegansINaP selective inhibition reverts precocious inter- and motorneurons hyperexcitability in the Sod1-G93R zebrafish ALS modelA genetic screening strategy identifies novel regulators of the proteostasis networkDrosophila as an In Vivo Model for Human Neurodegenerative DiseaseDetection of endogenous dopamine changes in Drosophila melanogaster using fast-scan cyclic voltammetryA genetic model of amyotrophic lateral sclerosis in zebrafish displays phenotypic hallmarks of motoneuron diseaseSynaptic abnormalities in a Drosophila model of Alzheimer's diseaseDifferential effects of phytotherapic preparations in the hSOD1 Drosophila melanogaster model of ALS.An automated climbing apparatus to measure chemotherapy-induced neurotoxicity in Drosophila melanogaster.Modelling amyotrophic lateral sclerosis: progress and possibilitiesTransgenic Drosophila models of Alzheimer's disease and tauopathiesAlzheimer's disease: insights from Drosophila melanogaster models.Drosophila melanogaster in the study of human neurodegeneration.Neurodegenerative models in Drosophila: polyglutamine disorders, Parkinson disease, and amyotrophic lateral sclerosis.Expression of zinc-deficient human superoxide dismutase in Drosophila neurons produces a locomotor defect linked to mitochondrial dysfunction.Flightless flies: Drosophila models of neuromuscular disease.β-N-methylamino-L-alanine induces neurological deficits and shortened life span in DrosophilaDietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease.PPAR gamma activation is neuroprotective in a Drosophila model of ALS based on TDP-43.A fruitful endeavor: modeling ALS in the fruit flyModel systems of motor neuron diseases as a platform for studying pathogenic mechanisms and searching for therapeutic agents.Drosophila models of proteinopathies: the little fly that could.Protein homeostasis in models of aging and age-related conformational disease.Temporal coherency between receptor expression, neural activity and AP-1-dependent transcription regulates Drosophila motoneuron dendrite development.Electrochemical Measurements of Optogenetically Stimulated Quantal Amine Release from Single Nerve Cell Varicosities in Drosophila Larvae.Transcriptome Profiling Following Neuronal and Glial Expression of ALS-Linked SOD1 in Drosophila.Insights into ALS pathomechanisms: from flies to humans.Drosophila melanogaster as a model organism of brain diseasesRecent advances in using Drosophila to model neurodegenerative diseases.ALS-linked SOD1 in glial cells enhances ß-N-Methylamino L-Alanine (BMAA)-induced toxicity in Drosophila.SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments.Modeling human neurodegenerative diseases in transgenic systems.Drosophila as a model to study the role of glia in neurodegeneration.The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span.Simple animal models for amyotrophic lateral sclerosis drug discovery.A network of genes connects polyglutamine toxicity to ploidy control in yeast
P2860
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P2860
A drosophila model for amyotrophic lateral sclerosis reveals motor neuron damage by human SOD1.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A drosophila model for amyotro ...... r neuron damage by human SOD1.
@en
type
label
A drosophila model for amyotro ...... r neuron damage by human SOD1.
@en
prefLabel
A drosophila model for amyotro ...... r neuron damage by human SOD1.
@en
P2093
P2860
P356
P1476
A drosophila model for amyotro ...... or neuron damage by human SOD1
@en
P2093
Bing Zhang
Kexiang Xu
Melanie R Watson
Robert D Lagow
P2860
P304
24972-24981
P356
10.1074/JBC.M804817200
P407
P577
2008-07-02T00:00:00Z