Targeting the alpha9alpha10 nicotinic acetylcholine receptor to treat severe pain.
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ConoServer: updated content, knowledge, and discovery tools in the conopeptide databaseConotoxin Interactions with α9α10-nAChRs: Is the α9α10-Nicotinic Acetylcholine Receptor an Important Therapeutic Target for Pain Management?α-RgIA, a Novel Conotoxin That Blocks the α9α10 nAChR: Structure and Identification of Key Receptor-Binding ResiduesFunctional expression of human α9* nicotinic acetylcholine receptors in X. laevis oocytes is dependent on the α9 subunit 5' UTR.Identification of a Novel O-Conotoxin Reveals an Unusual and Potent Inhibitor of the Human α9α10 Nicotinic Acetylcholine ReceptorStructure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channelsThe novel small molecule α9α10 nicotinic acetylcholine receptor antagonist ZZ-204G is analgesic.Novel small molecule α9α10 nicotinic receptor antagonist prevents and reverses chemotherapy-evoked neuropathic pain in rats.γ-Aminobutyric acid type B (GABAB) receptor expression is needed for inhibition of N-type (Cav2.2) calcium channels by analgesic α-conotoxinsMolecular basis for the differential sensitivity of rat and human α9α10 nAChRs to α-conotoxin RgIA.Strategies for the development of conotoxins as new therapeutic leads.Alpha9 nicotinic acetylcholine receptors and the treatment of pain.Finding new cures for neurological disorders: a possible fringe benefit of biodefense research?Analgesic and antineuropathic drugs acting through central cholinergic mechanismsSynthetic α-conotoxin mutants as probes for studying nicotinic acetylcholine receptors and in the development of novel drug leads.Novel thiazole derivatives: a patent review (2008 - 2012. Part 2).Recent Advances in Conotoxin Classification by Using Machine Learning Methods.A Transcriptomic Survey of Ion Channel-Based Conotoxins in the Chinese Tubular Cone Snail (Conus betulinus).α9-containing nicotinic acetylcholine receptors and the modulation of pain.A novel fluorescent alpha-conotoxin for the study of alpha7 nicotinic acetylcholine receptors.RgIA4 Potently Blocks Mouse α9α10 nAChRs and Provides Long Lasting Protection against Oxaliplatin-Induced Cold Allodynia.Nicotinic Acetylcholine Receptor α9 and α10 Subunits Are Expressed in the Brain of Mice.Discovery of non-peptide, small molecule antagonists of α9α10 nicotinic acetylcholine receptors as novel analgesics for the treatment of neuropathic and tonic inflammatory pain.Quantitative Structure Activity Relationship between Diazabicyclo[4.2.0]octanes Derivatives and Nicotinic Acetylcholine Receptor Agonists.Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain.Mitochondrial Nicotinic Acetylcholine Receptors Support Liver Cells Viability After Partial Hepatectomy.
P2860
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P2860
Targeting the alpha9alpha10 nicotinic acetylcholine receptor to treat severe pain.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Targeting the alpha9alpha10 nicotinic acetylcholine receptor to treat severe pain.
@en
type
label
Targeting the alpha9alpha10 nicotinic acetylcholine receptor to treat severe pain.
@en
prefLabel
Targeting the alpha9alpha10 nicotinic acetylcholine receptor to treat severe pain.
@en
P2860
P1476
Targeting the alpha9alpha10 nicotinic acetylcholine receptor to treat severe pain.
@en
P2093
J Michael McIntosh
Michelle Vincler
P2860
P304
P356
10.1517/14728222.11.7.891
P407
P577
2007-07-01T00:00:00Z