Polyomavirus and simian virus 40 large T antigens bind to common DNA sequences.
about
Simian virus 40 and polyomavirus large tumor antigens have different requirements for high-affinity sequence-specific DNA bindingPolyomavirus tumor induction in mice: influences of viral coding and noncoding sequences on tumor profiles.Insights into Polyomaviridae microRNA function derived from study of the bandicoot papillomatosis carcinomatosis viruses.DNA binding site for a factor(s) required to initiate simian virus 40 DNA replication.Zinc-binding and protein-protein interactions mediated by the polyomavirus large T antigen zinc finger.Protein domains connect cell cycle stimulation directly to initiation of DNA replication.Amplification mediated by polyomavirus large T antigen defective in replication.Mutation of large T-antigen-binding site A, but not site B or C, eliminates stalling by RNA polymerase II in the intergenic region of polyomavirus DNAThe DNA-binding properties of polyomavirus large T antigen are altered by ATP and other nucleotides.Activation of simian virus 40 transcription in vitro by T antigen.Identification of simian virus 40 T-antigen residues important for specific and nonspecific binding to DNA and for helicase activity.Four major sequence elements of simian virus 40 large T antigen coordinate its specific and nonspecific DNA binding.Intrachromosomal recombination mediated by papovavirus large T antigens.Determination of the origin-specific DNA-binding domain of polyomavirus large T antigen.Requirements for species-specific papovavirus DNA replication.Multiple subelements within the polyomavirus enhancer function synergistically to activate DNA replication.Sequences from polyomavirus and simian virus 40 large T genes capable of immortalizing primary rat embryo fibroblastsSimian virus 40 origin DNA-binding domain on large T antigen.Duplication of noncoding sequences in polyomavirus specifically augments the development of thymic tumors in miceRegulation of polyomavirus late promoter activity by viral early proteins.Immortalization of rat embryo fibroblasts by mutant polyomavirus large T antigens deficient in DNA binding.Construction of a helper-free recombinant adenovirus that expresses polyomavirus large T antigen.DNA sequence requirements for replication of polyomavirus DNA in vivo and in vitro.Isolation of large T antigen-producing mouse cell lines capable of supporting replication of polyomavirus-plasmid recombinants.Location of sequences in polyomavirus DNA that are required for early gene expression in vivo and in vitro.Regulation of polyomavirus transcription by large tumor antigen.Structural evaluation of new human polyomaviruses provides clues to pathobiology.Polyomavirus large T antigen binds cooperatively to its multiple binding sites in the viral origin of DNA replication.Sequences flanking the pentanucleotide T-antigen binding sites in the polyomavirus core origin help determine selectivity of DNA replication.Murine polyomavirus and simian virus 40 large T antigens produce different structural alterations in viral origin DNA.The mouse DNA polymerase alpha-primase subunit p48 mediates species-specific replication of polyomavirus DNA in vitro.Species-specific replication of simian virus 40 DNA in vitro requires the p180 subunit of human DNA polymerase alpha-primase.Guanine nucleotide contacts within viral DNA sequences bound by polyomavirus large T antigen.Simian agent 12 is a BK virus-like papovavirus which replicates in monkey cells.Overlapping redundant septuplets identical with regulatory elements of HIV-1 and SV40.Binding of polyomavirus large T antigen to the human hsp70 promoter is not required for trans activation.A unique subpopulation of murine DNA polymerase alpha/primase specifically interacts with polyomavirus T antigen and stimulates DNA replication.Cell specificity of transcription regulation by papovavirus T antigens and DNA replication.
P2860
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P2860
Polyomavirus and simian virus 40 large T antigens bind to common DNA sequences.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
1984年论文
@zh
1984年论文
@zh-cn
name
Polyomavirus and simian virus 40 large T antigens bind to common DNA sequences.
@en
type
label
Polyomavirus and simian virus 40 large T antigens bind to common DNA sequences.
@en
prefLabel
Polyomavirus and simian virus 40 large T antigens bind to common DNA sequences.
@en
P2860
P1433
P1476
Polyomavirus and simian virus 40 large T antigens bind to common DNA sequences
@en
P2093
Hassell JA
Pomerantz BJ
P2860
P304
P407
P577
1984-03-01T00:00:00Z