Sequences from polyomavirus and simian virus 40 large T genes capable of immortalizing primary rat embryo fibroblasts
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Identification of a region of simian virus 40 large T antigen required for cell transformationActivation of CREB/ATF sites by polyomavirus large T antigen.Cooperation of middle and small T antigens of polyomavirus in transformation of established fibroblast and epithelial-like cell lines.Simian virus 40 large T antigen contains two independent activities that cooperate with a ras oncogene to transform rat embryo fibroblastsGenetic analysis of polyomavirus large T nuclear localization: nuclear localization is required for productive association with pRb family members.A gene encoding a protein with zinc fingers is activated during G0/G1 transition in cultured cellsCellular transformation and malignancy induced by ras require c-jun.Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen.Association of p53 binding and immortalization of primary C57BL/6 mouse embryo fibroblasts by using simian virus 40 T-antigen mutants bearing internal overlapping deletion mutationsMutation of a cysteine residue in polyomavirus middle T antigen abolishes interactions with protein phosphatase 2A, pp60c-src, and phosphatidylinositol-3 kinase, activation of c-fos expression, and cellular transformation.Polyomavirus large T mutants affected in retinoblastoma protein binding are defective in immortalization.The T/t common region of simian virus 40 large T antigen contains a distinct transformation-governing sequence.Intrachromosomal recombination mediated by papovavirus large T antigens.JC virus-simian virus 40 genomes containing heterologous regulatory signals and chimeric early regions: identification of regions restricting transformation by JC virus.The large tumor antigen of simian virus 40 encodes at least two distinct transforming functions.Mutation in the polyomavirus genome that activates the properties of large T associated with neoplastic transformationAbility of a T-antigen transport-defective mutant of simian virus 40 to immortalize primary cells and to complement polyomavirus middle T in tumorigenesis.Phosphorylation of polyomavirus large T antigen: effects of viral mutations and cell growth state.Immortalization of rat embryo fibroblasts by mutant polyomavirus large T antigens deficient in DNA binding.Mutant p53 tumor suppressor alleles release ras-induced cell cycle growth arrest.The mRNA 5' cap-binding protein, eIF-4E, cooperates with v-myc or E1A in the transformation of primary rodent fibroblasts.J domain-independent regulation of the Rb family by polyomavirus large T antigenEffect on polyomavirus T-antigen function of mutations in a conserved leucine-rich segment of the DnaJ domainCharacterization of an immortalizing N-terminal domain of polyomavirus large T antigen.Primary rat cells expressing a hybrid polyomavirus-simian virus 40 large T antigen have altered growth properties.Polyomavirus large and small T antigens cooperate in induction of the S phase in serum-starved 3T3 mouse fibroblasts.Mutual functional antagonism of the simian virus 40 T antigen and the hepatitis B virus trans activator.
P2860
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P2860
Sequences from polyomavirus and simian virus 40 large T genes capable of immortalizing primary rat embryo fibroblasts
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
1985年论文
@zh
1985年论文
@zh-cn
name
Sequences from polyomavirus an ...... primary rat embryo fibroblasts
@en
type
label
Sequences from polyomavirus an ...... primary rat embryo fibroblasts
@en
prefLabel
Sequences from polyomavirus an ...... primary rat embryo fibroblasts
@en
P2860
P1433
P1476
Sequences from polyomavirus an ...... primary rat embryo fibroblasts
@en
P2093
P2860
P304
P407
P577
1985-12-01T00:00:00Z