Immunity in the female genital tract after intravaginal vaccination of mice with an attenuated strain of herpes simplex virus type 2
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A live-attenuated HSV-2 ICP0 virus elicits 10 to 100 times greater protection against genital herpes than a glycoprotein D subunit vaccineProtective Role of Fas-FasL Signaling in Lethal Infection with Herpes Simplex Virus Type 2 in MiceGenital HSV-2 infection induces short-term NK cell memoryHerpes simplex virus (HSV)-specific T cells activated in the absence of IFN-gamma express alternative effector functions but are not protective against genital HSV-2 infection.In vivo modulation of vaccine-induced immune responses toward a Th1 phenotype increases potency and vaccine effectiveness in a herpes simplex virus type 2 mouse model.NK and NKT cell-independent contribution of interleukin-15 to innate protection against mucosal viral infectionHerpes simplex virus type 2 vaccines: new ground for optimism?Mucosal immunity to herpes simplex virus type 2 infection in the mouse vagina is impaired by in vivo depletion of T lymphocytes.Immunoglobulin G, plasma cells, and lymphocytes in the murine vagina after vaginal or parenteral immunization with attenuated herpes simplex virus type 2Neutrophils aid in protection of the vaginal mucosae of immune mice against challenge with herpes simplex virus type 2.DNA vaccines encoding interleukin-8 and RANTES enhance antigen-specific Th1-type CD4(+) T-cell-mediated protective immunity against herpes simplex virus type 2 in vivoProtection against genital herpes infection in mice immunized under different hormonal conditions correlates with induction of vagina-associated lymphoid tissue.Vaccine-induced serum immunoglobin contributes to protection from herpes simplex virus type 2 genital infection in the presence of immune T cells.Interleukin-12 (IL-12) and IL-18 are important in innate defense against genital herpes simplex virus type 2 infection in mice but are not required for the development of acquired gamma interferon-mediated protective immunity.Long-term presence of virus-specific plasma cells in sensory ganglia and spinal cord following intravaginal inoculation of herpes simplex virus type 2.Efficacy of oral administration of live herpes simplex virus type 1 as a vaccine.Vaccination of mice and swine with a pseudorabies virus mutant lacking thymidine kinase activity.Clearance of herpes simplex virus type 2 by CD8+ T cells requires gamma interferon and either perforin- or Fas-mediated cytolytic mechanismsProgesterone increases susceptibility and decreases immune responses to genital herpes infection.Inhibitors of nucleotidyltransferase superfamily enzymes suppress herpes simplex virus replicationRecombinant vesicular stomatitis virus vectors expressing herpes simplex virus type 2 gD elicit robust CD4+ Th1 immune responses and are protective in mouse and guinea pig models of vaginal challenge.Transfer of IgG in the female genital tract by MHC class I-related neonatal Fc receptor (FcRn) confers protective immunity to vaginal infection.Topical herpes simplex virus 2 (HSV-2) vaccination with human papillomavirus vectors expressing gB/gD ectodomains induces genital-tissue-resident memory CD8+ T cells and reduces genital disease and viral shedding after HSV-2 challengeInduction of innate immunity against herpes simplex virus type 2 infection via local delivery of Toll-like receptor ligands correlates with beta interferon production.Local delivery of CpG oligodeoxynucleotides induces rapid changes in the genital mucosa and inhibits replication, but not entry, of herpes simplex virus type 2.Vaginal formulations of carrageenan protect mice from herpes simplex virus infection.Early resolution of herpes simplex virus type 2 infection of the murine genital tract involves stimulation of genital parenchymal cells by gamma interferonZinc acetate/carrageenan gels exhibit potent activity in vivo against high-dose herpes simplex virus 2 vaginal and rectal challenge.Herpes simplex virus type 2 virion host shutoff protein regulates alpha/beta interferon but not adaptive immune responses during primary infection in vivo.Mucosal model of immunization against human immunodeficiency virus type 1 with a chimeric influenza virusInduction of mucosal immunity against herpes simplex virus by plasmid DNA immunization.Abrogation of attenuated lentivirus-induced protection in rhesus macaques by administration of depo-provera before intravaginal challenge with simian immunodeficiency virus mac239Vaginal submucosal dendritic cells, but not Langerhans cells, induce protective Th1 responses to herpes simplex virus-2Prolonged exposure to progesterone prevents induction of protective mucosal responses following intravaginal immunization with attenuated herpes simplex virus type 2.Antiviral cytotoxic T lymphocytes in vaginal mucosa of simian immunodeficiency virus-infected rhesus macaquesIntravaginal immunization of mice with recombinant Salmonella enterica serovar Typhimurium expressing human papillomavirus type 16 antigens as a potential route of vaccination against cervical cancerHerpes simplex virus thymidine kinase and specific stages of latency in murine trigeminal ganglia.The herpes simplex virus type 1 (HSV-1) a sequence serves as a cleavage/packaging signal but does not drive recombinational genome isomerization when it is inserted into the HSV-2 genome.Replication-defective virus vaccine-induced protection of mice from genital herpes simplex virus 2 requires CD4 T cellsSynthetic α-Hydroxytropolones Inhibit Replication of Wild-Type and Acyclovir-Resistant Herpes Simplex Viruses.
P2860
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P2860
Immunity in the female genital tract after intravaginal vaccination of mice with an attenuated strain of herpes simplex virus type 2
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
1984年论文
@zh
1984年论文
@zh-cn
name
Immunity in the female genital ...... of herpes simplex virus type 2
@en
type
label
Immunity in the female genital ...... of herpes simplex virus type 2
@en
prefLabel
Immunity in the female genital ...... of herpes simplex virus type 2
@en
P2093
P2860
P1433
P1476
Immunity in the female genital ...... of herpes simplex virus type 2
@en
P2093
Bienenstock J
McDermott MR
Rudzroga HE
P2860
P304
P407
P577
1984-09-01T00:00:00Z