Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design.
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Control of PKA stability and signalling by the RING ligase praja2Investigation on quantitative structure activity relationships and pharmacophore modeling of a series of mGluR2 antagonistsA dynamic interface between ubiquitylation and cAMP signalingBacillus anthracis edema factor substrate specificity: evidence for new modes of actionAlterations of cAMP-dependent signaling in dystrophic skeletal muscleRPS23RG1 reduces Aβ oligomer-induced synaptic and cognitive deficits.Structure of Yeast Regulatory Subunit: A Glimpse into the Evolution of PKA SignalingAminoglycoside 2′′-Phosphotransferase IIIa (APH(2′′)-IIIa) Prefers GTP over ATPRole of N-Terminal Myristylation in the Structure and Regulation of cAMP-Dependent Protein KinaseAutoactivation of transforming growth factor beta-activated kinase 1 is a sequential bimolecular processEvolutionary paths of the cAMP-dependent protein kinase (PKA) catalytic subunitsA schistosome cAMP-dependent protein kinase catalytic subunit is essential for parasite viabilityIdentification of Toxoplasma gondii cAMP dependent protein kinase and its role in the tachyzoite growthcAMP-regulated protein lysine acetylases in mycobacteriaA functional mouse retroposed gene Rps23r1 reduces Alzheimer's beta-amyloid levels and tau phosphorylationSmall molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytesMuch ado about adenosine: adenosine synthesis and function in regulatory T cell biology.The cAMP-dependent protein kinase inhibitor H-89 attenuates the bioluminescence signal produced by Renilla Luciferase.Melanocyte-stimulating hormone directly enhances UV-Induced DNA repair in keratinocytes by a xeroderma pigmentosum group A-dependent mechanism.Phosphodiesterase Inhibitors as a Therapeutic Approach to Neuroprotection and Repair.TOR and PKA pathways synergize at the level of the Ste11 transcription factor to prevent mating and meiosis in fission yeast.(D)-Amino acid analogues of DT-2 as highly selective and superior inhibitors of cGMP-dependent protein kinase Ialpha.Experimental validation of FINDSITE(comb) virtual ligand screening results for eight proteins yields novel nanomolar and micromolar binders.Mys protein regulates protein kinase A activity by interacting with regulatory type Ialpha subunit during vertebrate developmentNFAT and CREB regulate Kaposi's sarcoma-associated herpesvirus-induced cyclooxygenase 2 (COX-2)The regulatory subunit of PKA-I remains partially structured and undergoes β-aggregation upon thermal denaturation.Developmental regulation of protein kinase A expression and activity in Schistosoma mansoniPhosphorylation of the protein kinase A catalytic subunit is induced by cyclic AMP deficiency and physiological stresses in the fission yeast, Schizosaccharomyces pombeProtein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule-1 mRNA.Signaling diversity of PKA achieved via a Ca2+-cAMP-PKA oscillatory circuit.Myosin-Va restrains the trafficking of Na+/K+-ATPase-containing vesicles in alveolar epithelial cellsDifferential Regulation of RasGAPs in Cancer.AKAPs: the architectural underpinnings of local cAMP signaling.A universal stress protein (USP) in mycobacteria binds cAMP.Direct modulation of the protein kinase A catalytic subunit α by growth factor receptor tyrosine kinases.Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Upregulates Ciliary Neurotrophic Factor in Astrocytes and Oligodendrocytes.PKA and PDE4D3 anchoring to AKAP9 provides distinct regulation of cAMP signals at the centrosome.Processing body and stress granule assembly occur by independent and differentially regulated pathways in Saccharomyces cerevisiaeAblation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterasesWnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways
P2860
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P2860
Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Signaling through cAMP and cAM ...... se strategies for drug design.
@en
type
label
Signaling through cAMP and cAM ...... se strategies for drug design.
@en
prefLabel
Signaling through cAMP and cAM ...... se strategies for drug design.
@en
P2093
P2860
P1476
Signaling through cAMP and cAM ...... rse strategies for drug design
@en
P2093
Cecilia Y Cheng
Natarajan Kannan
Susan S Taylor
P2860
P356
10.1016/J.BBAPAP.2007.10.002
P407
P577
2007-10-12T00:00:00Z