Three lymphoid-specific factors account for all junctional diversity characteristic of somatic assembly of T-cell receptor and immunoglobulin genes.
about
The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros geneDistinct requirements for Ku in N nucleotide addition at V(D)J- and non-V(D)J-generated double-strand breaksMechanistic constraints on diversity in human V(D)J recombinationDifferential splicing in mouse thymus generates two forms of terminal deoxynucleotidyl transferaseSelf-organized criticality theory of autoimmunityNucleotide pool imbalance and adenosine deaminase deficiency induce alterations of N-region insertions during V(D)J recombination.Initiation of V(D)J recombination in vivo: role of recombination signal sequences in formation of single and paired double-strand breaks.P nucleotide insertions and the resolution of hairpin DNA structures in mammalian cells.Predominance of fetal type DJH joining in young children with B precursor lymphoblastic leukemia as evidence for an in utero transforming event.The long isoform of terminal deoxynucleotidyl transferase enters the nucleus and, rather than catalyzing nontemplated nucleotide addition, modulates the catalytic activity of the short isoform.Most alpha/beta T cell receptor diversity is due to terminal deoxynucleotidyl transferaseV(D)J recombination: in vitro coding joint formation.P nucleotides in V(D)J recombination: a fine-structure analysis.Biased T-cell receptor delta element recombination in scid thymocytes.Regulation of N-region diversity in antigen receptors through thymocyte differentiation and thymus ontogeny.The two isoforms of mouse terminal deoxynucleotidyl transferase differ in both the ability to add N regions and subcellular localization.Both LyF-1 and an Ets protein interact with a critical promoter element in the murine terminal transferase gene.Strategies for B-cell receptor repertoire analysis in primary immunodeficiencies: from severe combined immunodeficiency to common variable immunodeficiency.The presence of direct repeats does not influence coding joint formation during V(D)J recombination.A potential role for Elf-1 in terminal transferase gene regulationNucleotide deletion and P addition in V(D)J recombination: a determinant role of the coding-end sequence.T-cell specific avian TdT: characterization of the cDNA and recombinant enzyme.The effects of transfected mutant and wild type RAG genes in different cell types.V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair.Terminal deoxynucleotidyl transferase indiscriminately incorporates ribonucleotides and deoxyribonucleotides.Terminal deoxynucleotidyl transferase is down-regulated by AP-1-like regulatory elements in human lymphoid cells.An evolutionary perspective on the systems of adaptive immunity.
P2860
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P2860
Three lymphoid-specific factors account for all junctional diversity characteristic of somatic assembly of T-cell receptor and immunoglobulin genes.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Three lymphoid-specific factor ...... ptor and immunoglobulin genes.
@en
type
label
Three lymphoid-specific factor ...... ptor and immunoglobulin genes.
@en
prefLabel
Three lymphoid-specific factor ...... ptor and immunoglobulin genes.
@en
P2093
P2860
P356
P1476
Three lymphoid-specific factor ...... ptor and immunoglobulin genes.
@en
P2093
Fanton d'Andon M
Kallenbach S
P2860
P304
P356
10.1073/PNAS.89.7.2799
P407
P577
1992-04-01T00:00:00Z