Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A.
about
A family of human cdc2-related protein kinasesTranscriptional activation of the cyclin A gene by the architectural transcription factor HMGA2PITALRE, a nuclear CDC2-related protein kinase that phosphorylates the retinoblastoma protein in vitroCdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin bindingIdentification of G1 kinase activity for cdk6, a novel cyclin D partnerHIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progressionp12(DOC-1) is a novel cyclin-dependent kinase 2-associated proteinCDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phaseThe consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2Phosphorylation of threonine 61 by cyclin a/Cdk1 triggers degradation of stem-loop binding protein at the end of S phaseIn vivo structure of the human cdc2 promoter: release of a p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expressionMechanisms of G2 arrest in response to overexpression of p53Sulindac sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cellsHuman immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activitySequential replication-coupled destruction at G1/S ensures genome stability.Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activityCyclin A is a c-Jun target gene and is necessary for c-Jun-induced anchorage-independent growth in RAT1a cellsCdc25A is a novel phosphatase functioning early in the cell cycleCell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15Effects of phosphorylation by CAK on cyclin binding by CDC2 and CDK2D-type cyclin-dependent kinase activity in mammalian cellsCyclin A/cdk2 regulates adenomatous polyposis coli-dependent mitotic spindle anchoring.A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: biochemical identification using Xenopus egg extractsNon-dependence of cyclin E/Cdk2 kinase activity on the initiation of oocyte maturation in goldfish.Safeguarding entry into mitosis: the antephase checkpoint.Cell cycle control, checkpoint mechanisms, and genotoxic stress.Phosphorylation of p21 in G2/M promotes cyclin B-Cdc2 kinase activity.Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)Meiotic cell cycle in Xenopus oocytes is independent of cdk2 kinase.Cell cycle and transcriptional control of human myeloid leukemic cells by transforming growth factor beta.Cdc25-dependent activation of cyclin A/cdk2 is blocked in G2 phase arrested cells independently of ATM/ATR.Cell cycle-dependent regulation of human DNA polymerase alpha-primase activity by phosphorylation.Reciprocal activation by cyclin-dependent kinases 2 and 7 is directed by substrate specificity determinants outside the T loop.The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologuesIntimal hyperplasia after vascular injury is inhibited by antisense cdk 2 kinase oligonucleotides.A kinase associated with chromatin that can be activated by ligand-p185c-Neu or epidermal growth factor-receptor interactions.Effects of seawater acidification on cell cycle control mechanisms in Strongylocentrotus purpuratus embryos.The cdc2-related protein p40MO15 is the catalytic subunit of a protein kinase that can activate p33cdk2 and p34cdc2Phorbol ester inhibits the phosphorylation of the retinoblastoma protein without suppressing cyclin D-associated kinase in vascular smooth muscle cells.Phosphorylation independent activation of human cyclin-dependent kinase 2 by cyclin A in vitro.
P2860
Q24300226-ABF4D47A-208A-4748-8DAF-7A3898E9D17FQ24300865-8FF73F6F-D3A0-4A8B-AABB-B485A1968929Q24312133-0AACC908-A705-41F8-AFA5-4CA5B44EF602Q24313280-A98C1B6F-703D-4B5B-8C08-4B3EC4695871Q24324587-ACA54D8F-D72C-4BC4-99BF-C87DFBC7C9BBQ24551005-DDD492C7-2B07-43A7-93B0-623340718C96Q24552098-517F53BF-F95A-4769-B4DE-2B6B71386C3BQ24554436-4EAE75CC-76F8-42C9-9477-7CB5D31E7A2FQ24561705-8A12F364-834E-48A8-8CFF-374C1FDE1FECQ24646532-726A56A8-E379-47CC-9C25-DE60E4DAC2C7Q24650986-9868EF42-83AB-4D05-A053-89E4C60EC018Q24654806-92514FB6-A7A1-454C-B749-4E5A9F85C828Q24683705-09B2F774-F7A1-495A-8847-E0AA68A026A8Q24685633-17010EA9-FE8C-4F4D-973B-DD75722308BBQ27322859-3C96A717-CDB6-49EE-AB66-439361EED2ACQ27617593-5B92C4B9-F598-4D6C-9F78-44C866CAA161Q28567264-C4139457-3154-4DFE-AF2B-76BD897C0A34Q28570620-65451C8E-F6B5-4700-B6BF-78ABFC6AE518Q28610294-F462D867-496F-471A-B723-67BA07B294AAQ28612903-F8A86C19-39A4-4DEC-8D1F-CEAFF702CA60Q29614966-F63DD5C3-84F4-43C3-ABF5-1EC99EFE248DQ30491807-116D7AF8-C7E4-4D67-9573-D7A38247A839Q30676818-3F84A995-6DCC-4DFF-A221-54119F42279EQ30887957-C8C5BD78-B38E-4396-A3C1-A5D83C1EC335Q33558235-0B5102E9-3286-4F13-AC4E-6A0B9EA33819Q33608768-AFF8C986-7D02-48CB-BB6A-08929B0C8E31Q33724384-F560C23E-EBEA-4FE6-958C-64AA49A17398Q33843707-ADB066E8-2F57-41AC-AA69-299949068BD3Q33886929-E72FCC69-7426-4045-BCA0-00F414746327Q33929808-A5091A1A-DFA7-4230-AE9F-E663842FA98EQ33943471-1F612EFF-D668-4F93-98AA-93804222FC9AQ33957212-5F0207F9-6696-4044-8FB5-9192DC80699BQ33975124-4AE905BF-6DCC-4148-BED5-E72E31A8DFE7Q34057186-EF193C4E-D208-477B-9BDD-AC757DCB8A24Q34138108-480B99D6-91DB-4BE0-8690-C119EFD50EE0Q34141500-85820576-E349-4DF1-A14D-041586690B72Q34222062-B1E8A440-CAFC-4685-9297-CBCD12D94FF7Q34356650-AB547F75-C290-474D-9B86-AF7F3A693254Q34378898-FFE74901-B189-4D59-8CC7-7A15697BA98EQ34435398-06F03D43-E49A-4362-9E3B-236F0737604C
P2860
Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Human cyclin-dependent kinase ...... and associates with cyclin A.
@en
type
label
Human cyclin-dependent kinase ...... and associates with cyclin A.
@en
prefLabel
Human cyclin-dependent kinase ...... and associates with cyclin A.
@en
P2860
P356
P1476
Human cyclin-dependent kinase ...... and associates with cyclin A.
@en
P2860
P304
P356
10.1073/PNAS.89.7.2824
P407
P50
P577
1992-04-01T00:00:00Z