Selective TRIF-dependent signaling by a synthetic toll-like receptor 4 agonist. - Wikidata - wikimedia - TriplyDB

Selective TRIF-dependent signaling by a synthetic toll-like receptor 4 agonist.

Selective TRIF-dependent signaling by a synthetic toll-like receptor 4 agonist.

http://www.wikidata.org/entity/Q36933812

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The SYK side of TLR4: signalling mechanisms in response to LPS and minimally oxidized LDL A structure-function approach to optimizing TLR4 ligands for human vaccines A Novel Agonist of the TRIF Pathway Induces a Cellular State Refractory to Replication of Zika, Chikungunya, and Dengue Viruses.Identification of Adjuvantic Activity of Amphotericin B in a Novel, Multiplexed, Poly-TLR/NLR High-Throughput Screen.Activation of innate immune responses by Haemophilus influenzae lipooligosaccharide Toll-like receptor 4 (TLR4) modulation by synthetic and natural compounds: an update.Structure-activity relationships in human Toll-like receptor 8-active 2,3-diamino-furo[2,3-c]pyridines.Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica Single-cell and population NF-κB dynamic responses depend on lipopolysaccharide preparation.Inefficient TLR4/MD-2 heterotetramerization by monophosphoryl lipid A Characterization of TRIF selectivity in the AGP class of lipid A mimetics: role of secondary lipid chains.Kdo2 -lipid A: structural diversity and impact on immunopharmacology.Type I interferon signaling contributes to the bias that Toll-like receptor 4 exhibits for signaling mediated by the adaptor protein TRIF.Adjuvants in the Driver's Seat: How Magnitude, Type, Fine Specificity and Longevity of Immune Responses Are Driven by Distinct Classes of Immune Potentiators Differential outcome of TRIF-mediated signaling in TLR4 and TLR3 induced DC maturation A unique host defense pathway: TRIF mediates both antiviral and antibacterial immune responses.Pharmacological characterization of the opioid inactive isomers (+)-naltrexone and (+)-naloxone as antagonists of toll-like receptor 4 TRIF mobilizes unique primary defense against Gram-negative bacteria in intestinal interface.HIV-1 Tat Protein Activates both the MyD88 and TRIF Pathways To Induce Tumor Necrosis Factor Alpha and Interleukin-10 in Human Monocytes.Src-kinase inhibitors sensitize human cells of myeloid origin to Toll-like-receptor-induced interleukin 12 synthesis.Adjuvant activity of naturally occurring monophosphoryl lipopolysaccharide preparations from mucosa-associated bacteria MyD88 and TRIF synergistic interaction is required for TH1-cell polarization with a synthetic TLR4 agonist adjuvant Intranasal vaccination promotes detrimental Th17-mediated immunity against influenza infection.The immunobiology of toll-like receptor 4 agonists: from endotoxin tolerance to immunoadjuvants.Adjuvants containing natural and synthetic Toll-like receptor 4 ligands.Directing the immune system with chemical compounds.Small-Molecule Carbohydrate-Based Immunostimulants.Old and new adjuvants.Synthesis of anti-inflammatory α-and β-linked acetamidopyranosides as inhibitors of toll-like receptor 4 (TLR4).TLR4 agonists as vaccine adjuvants: a chemist's perspective.TLR4-mediated pro-inflammatory dendritic cell differentiation in humans requires the combined action of MyD88 and TRIF.Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex.Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis.The Toll like receptor 4 ligand cold-inducible RNA-binding protein as vaccination platform against cancer.Improved vaccines through targeted manipulation of the body's immunological risk-assessment?

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P2860

Selective TRIF-dependent signaling by a synthetic toll-like receptor 4 agonist.

http://www.wikidata.org/entity/Q36933812

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Selective TRIF-dependent signaling by a synthetic toll-like receptor 4 agonist.

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type

label

Selective TRIF-dependent signaling by a synthetic toll-like receptor 4 agonist.

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prefLabel

Selective TRIF-dependent signaling by a synthetic toll-like receptor 4 agonist.

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SCISIGNAL.2001963

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Science Signaling

P1476

Selective TRIF-dependent signaling by a synthetic toll-like receptor 4 agonist

@en

P2093

David A Johnson

http://www.w3.org/2001/XMLSchema#string

Laurie A Minns

http://www.w3.org/2001/XMLSchema#string

Melinda M Hutton

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Thomas C Mitchell

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William S Bowen

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran

The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex

The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction

Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation

Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa

Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction

Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity

Clinical update of the AS04-adjuvanted human papillomavirus-16/18 cervical cancer vaccine, Cervarix

Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

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10.1126/SCISIGNAL.2001963

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211

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5

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2012-02-14T00:00:00Z

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221835554

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22337809

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Toll-like receptor

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3684200

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