Mutation causing premature termination of the polyoma virus medium T antigen blocks cell transformation.
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Serine 257 phosphorylation regulates association of polyomavirus middle T antigen with 14-3-3 proteinsPhosphorylation of polyoma middle T antigen and cellular proteins in purified plasma membranes of polyoma virus-infected cells.Polyoma middle-sized T antigen can be phosphorylated on tyrosine at multiple sites in vitro.Natural biology of polyomavirus middle T antigen.Lessons in signaling and tumorigenesis from polyomavirus middle T antigen.Phosphatidylinositol metabolism and polyoma-mediated transformation.Identification of regions in polyomavirus middle T and small t antigens important for association with protein phosphatase 2A.Expression of polyoma early gene products in E. coliCarboxy terminus of polyoma middle-sized tumor antigen is required for attachment to membranes, associated protein kinase activities, and cell transformationPurification of polyoma virus medium-size tumor antigen by immunoaffinity chromatographyCharacterization of pp85, a target of oncogenes and growth factor receptorsHigh-level recombination specific to polyomavirus genomes targeted to the integration-transformation pathwayA completely transformation-defective point mutant of polyomavirus middle T antigen which retains full associated phosphatidylinositol kinase activityAssociation of p62c-yes with polyomavirus middle T-antigen mutants correlates with transforming ability.The amino terminus of polyomavirus middle T antigen is required for transformation.Transcriptional regulation of early-response genes during polyomavirus infection.Truncated forms of the polyomavirus middle T antigen can substitute for the small T antigen in lytic infection.In vitro mutagenesis of the putative membrane-binding domain of polyomavirus middle-T antigen.Cellular proteins that associate with the middle and small T antigens of polyomavirus.Medium tumor antigen of polyomavirus transformation-defective mutant NG59 is associated with 73-kilodalton heat shock protein.Analysis of polyomavirus middle-T-antigen-transformed rat cell variants expressing different levels of pp60c-srcAbundant expression of polyomavirus middle T antigen and dihydrofolate reductase in an adenovirus recombinant.Structural and functional modification of pp60c-src associated with polyoma middle tumor antigen from infected or transformed cells.Large-scale production of polyoma middle T antigen by using genetically engineered tumors.Characterization of viable mutants of polyomavirus cold sensitive for maintenance of cell transformationTransformation of chicken embryo fibroblasts and tumor induction by the middle T antigen of polyomavirus carried in an avian retroviral vectorA 61,000-dalton truncated large T-antigen is uniformly expressed in hamster cells transformed by polyomavirus.Regulation of pp60c-src synthesis by inducible RNA complementary to c-src mRNA in polyomavirus-transformed rat cells.Analysis of middle tumor antigen and pp60c-src interactions in polyomavirus-transformed rat cells.Interactions between polyomavirus medium T antigen and three cellular proteins of 88, 61, and 37 kilodaltonsConstruction and expression of a recombinant DNA gene encoding a polyomavirus middle-size tumor antigen with the carboxyl terminus of the vesicular stomatitis virus glycoprotein G.N-terminal amino acid sequences of the polyoma middle-size T antigen are important for protein kinase activity and cell transformation.A polyoma mutant that encodes small T antigen but not middle T antigen demonstrates uncoupling of cell surface and cytoskeletal changes associated with cell transformation.Lessons from polyoma middle T antigen on signaling and transformation: A DNA tumor virus contribution to the war on cancer.Complexes of polyoma virus medium T antigen and cellular proteins.Novel monoclonal antibodies that differentiate between the binding of pp60c-src or protein phosphatase 2A by polyomavirus middle T antigen.Signaling from polyomavirus middle T and small T defines different roles for protein phosphatase 2A.Polyomavirus middle T antigen induces the transcription of osteopontin, a gene important for the migration of transformed cells.Myristylation of pp60c-src is not required for complex formation with polyomavirus middle-T antigen.Interactions of polyomavirus middle T with the SH2 domains of the pp85 subunit of phosphatidylinositol-3-kinase.
P2860
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P2860
Mutation causing premature termination of the polyoma virus medium T antigen blocks cell transformation.
description
1982 nî lūn-bûn
@nan
1982年の論文
@ja
1982年論文
@yue
1982年論文
@zh-hant
1982年論文
@zh-hk
1982年論文
@zh-mo
1982年論文
@zh-tw
1982年论文
@wuu
1982年论文
@zh
1982年论文
@zh-cn
name
Mutation causing premature ter ...... en blocks cell transformation.
@en
type
label
Mutation causing premature ter ...... en blocks cell transformation.
@en
prefLabel
Mutation causing premature ter ...... en blocks cell transformation.
@en
P2860
P1433
P1476
Mutation causing premature ter ...... gen blocks cell transformation
@en
P2093
D Templeton
P2860
P304
P407
P577
1982-03-01T00:00:00Z