Enhanced integrated stress response promotes myelinating oligodendrocyte survival in response to interferon-gamma
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The unfolded protein response in multiple sclerosisInhibition of GADD34, the stress-inducible regulatory subunit of the endoplasmic reticulum stress response, does not enhance functional recovery after spinal cord injuryIntegrating the mechanisms of apoptosis induced by endoplasmic reticulum stressExpression profiles of endoplasmic reticulum stress-related molecules in demyelinating lesions and multiple sclerosis.Youth and environmental enrichment generate serum exosomes containing miR-219 that promote CNS myelination.Interferon-γ inhibits central nervous system myelination through both STAT1-dependent and STAT1-independent pathwaysImpaired eukaryotic translation initiation factor 2B activity specifically in oligodendrocytes reproduces the pathology of vanishing white matter disease in mice.Interferon-γ activates nuclear factor-κ B in oligodendrocytes through a process mediated by the unfolded protein response.Promoting remyelination: utilizing a viral model of demyelination to assess cell-based therapiesUsing temporal genetic switches to synchronize the unfolded protein response in cell populations in vivo.Endoplasmic reticulum stress in disorders of myelinating cells.Neurotrophin-3 targets the translational initiation machinery in oligodendrocytes.Oligodendrocyte progenitors reversibly exit the cell cycle and give rise to astrocytes in response to interferon-γ.Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeuticPancreatic endoplasmic reticulum kinase activation promotes medulloblastoma cell migration and invasion through induction of vascular endothelial growth factor AcFLIP is critical for oligodendrocyte protection from inflammationCXCR2 signaling and host defense following coronavirus-induced encephalomyelitis.OLA1 regulates protein synthesis and integrated stress response by inhibiting eIF2 ternary complex formation.Attenuating the endoplasmic reticulum stress response improves functional recovery after spinal cord injury.Phasic Treatment with Interferon Gamma Stimulates Release of Exosomes that Protect Against Spreading Depression.Endoplasmic reticulum stress is important for the manifestations of α-synucleinopathy in vivo.ER Chaperone BiP/GRP78 Is Required for Myelinating Cell Survival and Provides Protection during Experimental Autoimmune Encephalomyelitis.Harnessing the integrated stress response for the treatment of multiple sclerosis.Resetting translational homeostasis restores myelination in Charcot-Marie-Tooth disease type 1B miceOligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis.Overexpression of CHOP in Myelinating Cells Does Not Confer a Significant Phenotype under Normal or Metabolic Stress Conditions.Regulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytesRestoring endoplasmic reticulum homeostasis improves functional recovery after spinal cord injury.CXCR2 signaling protects oligodendrocyte progenitor cells from IFN-γ/CXCL10-mediated apoptosisCHOP and the endoplasmic reticulum stress response in myelinating gliaPERK activation preserves the viability and function of remyelinating oligodendrocytes in immune-mediated demyelinating diseasesDual role of the integrated stress response in medulloblastoma tumorigenesis.ER Dysfunction and Protein Folding Stress in ALS.Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases.Signaling pathways from the endoplasmic reticulum and their roles in diseaseNF-κB activation protects oligodendrocytes against inflammation.Endoplasmic reticulum stress and the unfolded protein response in disorders of myelinating gliaGenetic inactivation of PERK signaling in mouse oligodendrocytes: normal developmental myelination with increased susceptibility to inflammatory demyelination.The immunity-related GTPase Irgm3 relieves endoplasmic reticulum stress response during coxsackievirus B3 infection via a PI3K/Akt dependent pathway.PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz.
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Enhanced integrated stress response promotes myelinating oligodendrocyte survival in response to interferon-gamma
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Enhanced integrated stress res ...... n response to interferon-gamma
@en
type
label
Enhanced integrated stress res ...... n response to interferon-gamma
@en
prefLabel
Enhanced integrated stress res ...... n response to interferon-gamma
@en
P2860
P50
P1476
Enhanced integrated stress res ...... n response to interferon-gamma
@en
P2093
Phillip E Kunkler
P2860
P304
P356
10.2353/AJPATH.2008.080449
P407
P577
2008-09-25T00:00:00Z