Impaired eukaryotic translation initiation factor 2B activity specifically in oligodendrocytes reproduces the pathology of vanishing white matter disease in mice.

Impaired eukaryotic translation initiation factor 2B activity specifically in oligodendrocytes reproduces the pathology of vanishing white matter disease in mice.

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http://www.wikidata.org/entity/Q34123857
The unfolded protein response in multiple sclerosisAstrocytes are central in the pathomechanisms of vanishing white matterImpaired eIF2B activity in ligodendrocytes contributes to VWMD pathogenesis.Pancreatic endoplasmic reticulum kinase activation promotes medulloblastoma cell migration and invasion through induction of vascular endothelial growth factor AInhibition of Vascular Endothelial Growth Factor Receptor 2 Exacerbates Loss of Lower Motor Neurons and Axons during Experimental Autoimmune Encephalomyelitis.A Missense Mutation in PPP1R15B Causes a Syndrome Including Diabetes, Short Stature, and MicrocephalyRegulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytesDual role of the integrated stress response in medulloblastoma tumorigenesis.Endoplasmic reticulum stress and the unfolded protein response in disorders of myelinating gliaInherited and acquired disorders of myelin: The underlying myelin pathology.Protein kinase R(PKR)-like endoplasmic reticulum kinase (PERK) inhibitors: a patent review (2010-2015).Molecular Determinants of the Regulation of Development and Metabolism by Neuronal eIF2α Phosphorylation in Caenorhabditis elegans.Endoplasmic Reticulum Protein Quality Control Failure in Myelin Disorders.Activating transcription factor 6α deficiency exacerbates oligodendrocyte death and myelin damage in immune-mediated demyelinating diseases.EIF2B2 mutations in Vanishing White Matter Disease hyper- suppress translation and delay recovery during the integrated stress response.
P2860

Impaired eukaryotic translation initiation factor 2B activity specifically in oligodendrocytes reproduces the pathology of vanishing white matter disease in mice.

Item
http://www.wikidata.org/entity/Q34123857
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Impaired eukaryotic translatio ...... white matter disease in mice.
@ast
Impaired eukaryotic translatio ...... white matter disease in mice.
@en
Impaired eukaryotic translatio ...... white matter disease in mice.
@nl
type
label
Impaired eukaryotic translatio ...... white matter disease in mice.
@ast
Impaired eukaryotic translatio ...... white matter disease in mice.
@en
Impaired eukaryotic translatio ...... white matter disease in mice.
@nl
prefLabel
Impaired eukaryotic translatio ...... white matter disease in mice.
@ast
Impaired eukaryotic translatio ...... white matter disease in mice.
@en
Impaired eukaryotic translatio ...... white matter disease in mice.
@nl
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Impaired eukaryotic translatio ...... white matter disease in mice.
@en
P2093
P2860
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10.1523/JNEUROSCI.1373-14.2014
P407
P433
P478
P50
P577
P698
P921
P932