A parasite cysteine protease is key to host protein degradation and iron acquisition.
about
Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug DesignCrystal Structures of TbCatB and Rhodesain, Potential Chemotherapeutic Targets and Major Cysteine Proteases of Trypanosoma bruceiCytosolic peroxidases protect the lysosome of bloodstream African trypanosomes from iron-mediated membrane damageMining a cathepsin inhibitor library for new antiparasitic drug leadsCathepsin-L can resist lysis by human serum in Trypanosoma brucei bruceiPreliminary molecular characterization of the human pathogen Angiostrongylus cantonensisAssessing the trypanocidal potential of natural and semi-synthetic diketopiperazines from two deep water marine-derived fungi.CPDB: cysteine protease annotation database in Leishmania species.The oligopeptidase B of Leishmania regulates parasite enolase and immune evasion.A cell-surface phylome for African trypanosomes.Cathepsin Gene Family Reveals Transcriptome Patterns Related to the Infective Stages of the Salmon Louse Caligus rogercresseyi.Integrated Activity and Genetic Profiling of Secreted Peptidases in Cryptococcus neoformans Reveals an Aspartyl Peptidase Required for Low pH Survival and Virulence.Excretion/secretion products from Schistosoma mansoni adults, eggs and schistosomula have unique peptidase specificity profiles.Non-canonical maturation of two papain-family proteases in Toxoplasma gondii.Cathepsin proteases in Toxoplasma gondii.Iron metabolism in trypanosomatids, and its crucial role in infection.State of the art in African trypanosome drug discovery.Drug targets in Leishmania.A co-evolutionary arms race: trypanosomes shaping the human genome, humans shaping the trypanosome genome.Iron Homeostasis and Trypanosoma brucei Associated Immunopathogenicity Development: A Battle/Quest for Iron.Molecular characterization of serine protease inhibitor isoform 3, SmSPI, from Schistosoma mansoni.Nicotinamide inhibits the lysosomal cathepsin b-like protease and kills African trypanosomes.Trypanosoma brucei brucei: endocytic recycling is important for mouse infectivity.Design, synthesis and biological evaluation of potent azadipeptide nitrile inhibitors and activity-based probes as promising anti-Trypanosoma brucei agents.Development of antitrypanosomal and antiplasmodial nonpeptidic cysteine protease inhibitors based on N-protected-guanidino-furan and -pyrrole building blocks.Two key cathepsins, TgCPB and TgCPL, are targeted by the vinyl sulfone inhibitor K11777 in in vitro and in vivo models of toxoplasmosis.Identification of cysteine protease inhibitors as new drug leads against Naegleria fowleri.Phylogenetic relationships, stage-specific expression and localisation of a unique family of inactive cysteine proteases in Sarcoptes scabiei.Cysteine proteases in protozoan parasites
P2860
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P2860
A parasite cysteine protease is key to host protein degradation and iron acquisition.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A parasite cysteine protease is key to host protein degradation and iron acquisition.
@en
type
label
A parasite cysteine protease is key to host protein degradation and iron acquisition.
@en
prefLabel
A parasite cysteine protease is key to host protein degradation and iron acquisition.
@en
P2093
P2860
P356
P1476
A parasite cysteine protease is key to host protein degradation and iron acquisition.
@en
P2093
Anthony J O'Donoghue
Charles S Craik
Conor R Caffrey
Richard D Fetter
Theresa C O'Brien
Youngchool Choe
P2860
P304
28934-28943
P356
10.1074/JBC.M805824200
P407
P577
2008-08-13T00:00:00Z