Translation initiation factor 2gamma mutant alters start codon selection independent of Met-tRNA binding.
about
'Ribozoomin'--translation initiation from the perspective of the ribosome-bound eukaryotic initiation factors (eIFs)eIF2γ mutation that disrupts eIF2 complex integrity links intellectual disability to impaired translation initiation.Cwf16p Associating with the Nineteen Complex Ensures Ordered Exon Joining in Constitutive Pre-mRNA Splicing in Fission YeastMolecular view of 43 S complex formation and start site selection in eukaryotic translation initiationPhosphorylation stoichiometries of human eukaryotic initiation factorsThe beta/Gcd7 subunit of eukaryotic translation initiation factor 2B (eIF2B), a guanine nucleotide exchange factor, is crucial for binding eIF2 in vivoThe mechanism of eukaryotic translation initiation: new insights and challengesFine mapping of complex traits in non-model species: using next generation sequencing and advanced intercross lines in Japanese quail.Molecular mechanism of scanning and start codon selection in eukaryotes.Phosphorylation of human eukaryotic initiation factor 2γ: novel site identification and targeted PKC involvement.An eIF2α-binding motif in protein phosphatase 1 subunit GADD34 and its viral orthologs is required to promote dephosphorylation of eIF2α.The β-hairpin of 40S exit channel protein Rps5/uS7 promotes efficient and accurate translation initiation in vivo.Coordinated movements of eukaryotic translation initiation factors eIF1, eIF1A, and eIF5 trigger phosphate release from eIF2 in response to start codon recognition by the ribosomal preinitiation complexβ-Hairpin loop of eukaryotic initiation factor 1 (eIF1) mediates 40 S ribosome binding to regulate initiator tRNA(Met) recruitment and accuracy of AUG selection in vivo.Conserved residues in yeast initiator tRNA calibrate initiation accuracy by regulating preinitiation complex stability at the start codon.Protein phosphatase PP1/GLC7 interaction domain in yeast eIF2γ bypasses targeting subunit requirement for eIF2α dephosphorylationSliding of a 43S ribosomal complex from the recognized AUG codon triggered by a delay in eIF2-bound GTP hydrolysiseIF2β is critical for eIF5-mediated GDP-dissociation inhibitor activity and translational control.Influence of translation factor activities on start site selection in six different mRNAs.Rps3/uS3 promotes mRNA binding at the 40S ribosome entry channel and stabilizes preinitiation complexes at start codons.EIF2S3 Mutations Associated with Severe X-Linked Intellectual Disability Syndrome MEHMO.eIF1A residues implicated in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites in yeast.eIF1 Loop 2 interactions with Met-tRNAi control the accuracy of start codon selection by the scanning preinitiation complex.
P2860
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P2860
Translation initiation factor 2gamma mutant alters start codon selection independent of Met-tRNA binding.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Translation initiation factor ...... dependent of Met-tRNA binding.
@en
type
label
Translation initiation factor ...... dependent of Met-tRNA binding.
@en
prefLabel
Translation initiation factor ...... dependent of Met-tRNA binding.
@en
P2860
P356
P1476
Translation initiation factor ...... ndependent of Met-tRNA binding
@en
P2093
Pankaj V Alone
P2860
P304
P356
10.1128/MCB.01147-08
P407
P50
P577
2008-09-15T00:00:00Z