Characterization of the human c-fms gene product and its expression in cells of the monocyte-macrophage lineage.
about
Mona, a novel hematopoietic-specific adaptor interacting with the macrophage colony-stimulating factor receptor, is implicated in monocyte/macrophage development.FMS mutations in myelodysplastic, leukemic, and normal subjectsMolecular cloning, expression, and chromosomal localization of the gene encoding a human myeloid membrane antigen (gp150)Interactions of phosphatidylinositol kinase, GTPase-activating protein (GAP), and GAP-associated proteins with the colony-stimulating factor 1 receptorDifferential transcription of exon 1 of the human c-fms gene in placental trophoblasts and monocytesSuppressor of cytokine signaling 1 interacts with the macrophage colony-stimulating factor receptor and negatively regulates its proliferation signalTyrosine phosphorylations in vivo associated with v-fms transformation.The unique insert of cellular and viral fms protein tyrosine kinase domains is dispensable for enzymatic and transforming activitiesSequential activation of phoshatidylinositol 3-kinase and phospholipase C-gamma2 by the M-CSF receptor is necessary for differentiation signalingHigh expression of macrophage colony-stimulating factor-1 receptor in peritumoral liver tissue is associated with poor outcome in hepatocellular carcinoma after curative resectionAberrant expression of T cell and B cell markers in myelocyte/monocyte/histiocyte-derived lymphoma and leukemia cells. Is the infrequent expression of T/B cell markers sufficient to establish a lymphoid origin for Hodgkin's Reed-Sternberg cells?G-CSF and M-CSF: from molecular biology to clinical application.Posttranscriptional stabilization of c-fms mRNA by a labile protein during human monocytic differentiationLigand and protein kinase C downmodulate the colony-stimulating factor 1 receptor by independent mechanismsLigand-induced tyrosine kinase activity of the colony-stimulating factor 1 receptor in a murine macrophage cell lineInduction of macrophage colony-stimulating factor-dependent growth and differentiation after introduction of the murine c-fms gene into FDC-P1 cells.Analysis of functional domains of the v-fms-encoded protein of Susan McDonough strain feline sarcoma virus by linker insertion mutagenesisTransformation by the v-fms oncogene product: role of glycosylational processing and cell surface expression.Expression of the human c-fms proto-oncogene product (colony-stimulating factor-1 receptor) on peripheral blood mononuclear cells and choriocarcinoma cell linesExpression of c-myc and c-fms oncogenes in trophoblastic cells in hydatidiform mole and normal human placenta."Replacement" of COOH-terminal truncation of v-fms with c-fms sequences markedly reduces transformation potential.Molecular biology and respiratory disease. 4. Cancer genesFMS Kinase Inhibitors: Current Status and Future Prospects.Proto-oncogenes and differentiation versus transformation of striated muscle cells.Cell-based biological evaluation of a new bisamide FMS kinase inhibitor possessing pyrrolo[3,2-c]pyridine scaffold.Transformation by the v-fms oncogene product: an analog of the CSF-1 receptor.Human cancer and cellular oncogenes.Activation of cellular oncogenes in human and mouse leukemia-lymphomas: spontaneous and induced oncogene expression in murine B lymphocytic neoplasms.The interferon-inducible gene, Ifi204, is transcriptionally activated in response to M-CSF, and its expression favors macrophage differentiation in myeloid progenitor cells.Purification and identification of protein-tyrosine kinase-binding proteins using synthetic phosphopeptides as affinity reagents.cDNA microarray analysis of invasive and tumorigenic phenotypes in a breast cancer model.gp140v-fms molecules expressed at the surface of cells transformed by the McDonough strain of feline sarcoma virus are phosphorylated in tyrosine and serine.Identification of tyrosine-phosphorylated colony-stimulating factor 1 (CSF-1) receptor and a 56-kilodalton protein phosphorylated in intact human cells in response to CSF-1.Localization and expression of CSF-1 receptor in rat dental follicle cells.Pyrrolo[3,2-c]pyridine derivatives with potential inhibitory effect against FMS kinase: in vitro biological studies
P2860
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P2860
Characterization of the human c-fms gene product and its expression in cells of the monocyte-macrophage lineage.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
1985年论文
@zh
1985年论文
@zh-cn
name
Characterization of the human ...... e monocyte-macrophage lineage.
@en
type
label
Characterization of the human ...... e monocyte-macrophage lineage.
@en
prefLabel
Characterization of the human ...... e monocyte-macrophage lineage.
@en
P2093
P2860
P356
P1476
Characterization of the human ...... e monocyte-macrophage lineage.
@en
P2093
J Woolford
L Rohrschneider
V Rothwell
P2860
P304
P356
10.1128/MCB.5.12.3458
P407
P577
1985-12-01T00:00:00Z