Zn2+ influx is critical for some forms of spreading depression in brain slices.
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Abnormal synaptic Ca(2+) homeostasis and morphology in cortical neurons of familial hemiplegic migraine type 1 mutant miceSpreading Depression, Spreading Depolarizations, and the Cerebral VasculatureSpreading depression and related events are significant sources of neuronal Zn2+ release and accumulation.Regulation of neuronal pH by the metabotropic Zn(2+)-sensing Gq-coupled receptor, mZnR/GPR39.Cortical spreading depression-new insights and persistent questions.Cytosolic zinc release and clearance in hippocampal neurons exposed to glutamate--the role of pH and sodium.Zn²+ chelation improves recovery by delaying spreading depression-like events.Hypoxia limits inhibitory effects of Zn2+ on spreading depolarizations.Characterization of inhibitory GABA-A receptor activation during spreading depolarization in brain slice.Upregulation of KCC2 activity by zinc-mediated neurotransmission via the mZnR/GPR39 receptorChloride Cotransporters as a Molecular Mechanism underlying Spreading Depolarization-Induced Dendritic BeadingSynaptic release and extracellular actions of Zn2+ limit propagation of spreading depression and related events in vitro and in vivoA role of the sodium pump in spreading ischemia in rats.Intracellular dialysis disrupts Zn2+ dynamics and enables selective detection of Zn2+ influx in brain slice preparations.Intracellular Zn2+ accumulation contributes to synaptic failure, mitochondrial depolarization, and cell death in an acute slice oxygen-glucose deprivation model of ischemia.Intracellular Zn2+ increases contribute to the progression of excitotoxic Ca2+ increases in apical dendrites of CA1 pyramidal neuronsRegenerative glutamate release by presynaptic NMDA receptors contributes to spreading depression.Intracellular zinc inhibits KCC2 transporter activityContributions of Ca2+ and Zn2+ to spreading depression-like events and neuronal injury.Ciliary neurotrophic factor (CNTF) activation of astrocytes decreases spreading depolarization susceptibility and increases potassium clearance.Zinc: new clues to diverse roles in brain ischemia.Contribution of calcium-conducting channels to the transport of zinc ions.Temporal fate specification and neural progenitor competence during development.The role of intracellular zinc release in aging, oxidative stress, and Alzheimer's disease.Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group.Contribution of astrocyte glycogen stores to progression of spreading depression and related events in hippocampal slices.Vascular, electrophysiological, and metabolic consequences of cortical spreading depression in a mouse model of simulated neurosurgical conditionsChanges in membrane potential and the intracellular calcium concentration during CSD and OGD in layer V and layer II/III mouse cortical neurons.The continuum of spreading depolarizations in acute cortical lesion development: Examining Leão's legacy.Effects of Glia in a Triphasic Continuum Model of Cortical Spreading Depression.Evidence that adenosine contributes to Leao's spreading depression in vivo.Sustained NMDA receptor activation by spreading depolarizations can initiate excitotoxic injury in metabolically compromised neurons.Understanding Spreading Depression from Headache to Sudden Unexpected Death.The Zinc Ion Chelating Agent TPEN Attenuates Neuronal Death/apoptosis Caused by Hypoxia/ischemia Via Mediating the Pathophysiological Cascade Including Excitotoxicity, Oxidative Stress, and Inflammation.The negative ultraslow potential, electrophysiological correlate of infarction in the human cortex.Control of Spreading Depression with Electrical Fields.Spreading depolarization, a pathophysiological mechanism of stroke and migraine aura
P2860
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P2860
Zn2+ influx is critical for some forms of spreading depression in brain slices.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Zn2+ influx is critical for some forms of spreading depression in brain slices.
@en
type
label
Zn2+ influx is critical for some forms of spreading depression in brain slices.
@en
prefLabel
Zn2+ influx is critical for some forms of spreading depression in brain slices.
@en
P2093
P2860
P1476
Zn2+ influx is critical for some forms of spreading depression in brain slices.
@en
P2093
Claude W Shuttleworth
John H Weiss
Robert M Dietz
P2860
P304
P356
10.1523/JNEUROSCI.0765-08.2008
P407
P577
2008-08-01T00:00:00Z