Post-translational regulation of the 54K cellular tumor antigen in normal and transformed cells
about
Isolation and characterization of a human p53 cDNA clone: expression of the human p53 geneMolecular cloning of a cDNA specific for the murine p53 cellular tumor antigenUV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cellsViruses associated with human cancerSimian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 bindingHuman papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcriptionp300 family members associate with the carboxyl terminus of simian virus 40 large tumor antigenInteractions between p53 and MDM2 in a mammalian cell cycle checkpoint pathwaymdm2 expression is induced by wild type p53 activityAltered processing of a major secreted phosphoprotein correlates with tumorigenicity in Rous sarcoma virus-transformed mammalian cells.Potential role of p53 mutation in chemical hepatocarcinogenesis of rats.Interaction of the human papillomavirus type 16 E6 oncoprotein with wild-type and mutant human p53 proteinsHuman cytomegalovirus and human herpesvirus 6 genes that transform and transactivateHuman p53 oncogene contains one promoter upstream of exon 1 and a second, stronger promoter within intron 1.Cotransfection of granulosa cells with simian virus 40 and Ha-RAS oncogene generates stable lines capable of induced steroidogenesis.Human papillomavirus type 16 E6 increases the degradation rate of p53 in human keratinocytesIntestinal dysplasia induced by simian virus 40 T antigen is independent of p53.Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis.Wild-type, but not mutant, human p53 proteins inhibit the replication activities of simian virus 40 large tumor antigen.Permanent expression of p53 in FR 3T3 rat cells but cell cycle-dependent association with large-T antigen in simian virus 40 transformants.P53 transformation-related protein accumulates in the nucleus of transformed fibroblasts in association with the chromatin and is found in the cytoplasm of non-transformed fibroblasts.Monoclonal antibodies displaying a novel species specificity for the primate transformation-related protein, p53.Targeted degradation of the retinoblastoma protein by human papillomavirus E7-E6 fusion proteins.The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein.Induction of interferon-stimulated genes by Simian virus 40 T antigens.A single gene and a pseudogene for the cellular tumour antigen p53.Limiting the power of p53 through the ubiquitin proteasome pathway.Rearrangement of the p53 gene in human osteogenic sarcomasPrecise epitope mapping of the murine transformation-associated protein, p53.Inducible growth arrest: new mechanistic insights.Regulation of apoptosis in transgenic mice by simian virus 40 T antigen-mediated inactivation of p53.p53 loss of function: implications for the processes of immortalization and tumorigenesis.Molecular biology in the diagnosis and prognosis of solid and lymphoid tumors.Qualitative network modeling of the Myc-p53 control system of cell proliferation and differentiationRegulation by proteolysis: energy-dependent proteases and their targets.Classification of hepatocellular carcinoma according to hepatocellular and biliary differentiation markers. Clinical and biological implications.The MDM2 oncoprotein is overexpressed in rhabdomyosarcoma cell lines and stabilizes wild-type p53 protein.Simian virus 40 large T antigen contains two independent activities that cooperate with a ras oncogene to transform rat embryo fibroblastsHuman cytomegalovirus mtrII oncoprotein binds to p53 and down-regulates p53-activated transcription.Stabilization and activation of p53 are regulated independently by different phosphorylation events.
P2860
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P2860
Post-translational regulation of the 54K cellular tumor antigen in normal and transformed cells
description
1981 nî lūn-bûn
@nan
1981年の論文
@ja
1981年論文
@yue
1981年論文
@zh-hant
1981年論文
@zh-hk
1981年論文
@zh-mo
1981年論文
@zh-tw
1981年论文
@wuu
1981年论文
@zh
1981年论文
@zh-cn
name
Post-translational regulation ...... n normal and transformed cells
@en
type
label
Post-translational regulation ...... n normal and transformed cells
@en
prefLabel
Post-translational regulation ...... n normal and transformed cells
@en
P2093
P2860
P356
P1476
Post-translational regulation ...... n normal and transformed cells
@en
P2093
P2860
P304
P356
10.1128/MCB.1.2.101
P407
P577
1981-02-01T00:00:00Z