Human papillomavirus type 16 E6 increases the degradation rate of p53 in human keratinocytes
about
Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53Viruses associated with human cancerHPV-p53-miR-34a axis in HPV-associated cancersMultiple functions of human papillomavirus type 16 E6 contribute to the immortalization of mammary epithelial cellsElucidating Molecular Interactions of Natural Inhibitors with HPV-16 E6 Oncoprotein through Docking AnalysisHPV and p53 in cervical cancer.Localisation of human papillomavirus 16 E7 oncoprotein changes with cell confluence.Enhanced degradation of p53 protein in HPV-6 and BPV-1 E6-immortalized human mammary epithelial cells.Pathogenesis of human papillomaviruses in differentiating epithelia.A mutant of human papillomavirus type 16 E6 deficient in binding alpha-helix partners displays reduced oncogenic potential in vivo.E2 proteins from high- and low-risk human papillomavirus types differ in their ability to bind p53 and induce apoptotic cell death.Adeno-associated virus type 2 increases proteosome-dependent degradation of p21WAF1 in a human papillomavirus type 31b-positive cervical carcinoma linep63 is necessary for the activation of human papillomavirus late viral functions upon epithelial differentiation.Molecular events in uterine cervical cancer.The p53-Mdm2 association in epithelial cells in idiopathic pulmonary fibrosis and non-specific interstitial pneumonia.Regulation of synoviocyte proliferation, apoptosis, and invasion by the p53 tumor suppressor geneInhibition of HPV-16 E6/E7 immortalization of normal keratinocytes by hairpin ribozymes.In Silico Docking to Explicate Interface between Plant-Originated Inhibitors and E6 Oncogenic Protein of Highly Threatening Human Papillomavirus 18.Mutational analysis of human papillomavirus type 16 E6 demonstrates that p53 degradation is necessary for immortalization of mammary epithelial cells.Alteration of cell cycle kinase complexes in human papillomavirus E6- and E7-expressing fibroblasts precedes neoplastic transformationSerum- and calcium-induced differentiation of human keratinocytes is inhibited by the E6 oncoprotein of human papillomavirus type 16.Comprehensive analysis of host cellular interactions with human papillomavirus E6 proteins identifies new E6 binding partners and reflects viral diversityReversible repression of papillomavirus oncogene expression in cervical carcinoma cells: consequences for the phenotype and E6-p53 and E7-pRB interactionsRepression of endogenous p53 transactivation function in HeLa cervical carcinoma cells by human papillomavirus type 16 E6, human mdm-2, and mutant p53Inhibition of cervical carcinoma cell line proliferation by the introduction of a bovine papillomavirus regulatory geneIdentification and characterization of novel promoters in the genome of human papillomavirus type 18.Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.Positive and negative regulation of cell proliferation by E2F-1: influence of protein level and human papillomavirus oncoproteinsLocalization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteinsHuman papillomaviruses and cervical neoplasia. II. Interaction of HPV with other factors.A systematic review of p53 as a prognostic factor of survival in squamous cell carcinoma of the four main anatomical subsites of the head and neck.CTS1: a p53-derived chimeric tumor suppressor gene with enhanced in vitro apoptotic properties.Radiation response in two HPV-infected head-and-neck cancer cell lines in comparison to a non-HPV-infected cell line and relationship to signaling through AKT.The ability of human papillomavirus E6 proteins to target p53 for degradation in vivo correlates with their ability to abrogate actinomycin D-induced growth arrest.HPV16 E6 confers p53-dependent and p53-independent phenotypes in the epidermis of mice deficient for E6AP.
P2860
Q24321129-410851F3-4FA6-4D0C-B2AB-32A27616F3BAQ24653900-A1221CF7-EB0C-49E7-A1D9-E944BF7C3E97Q26770487-9C9AEED3-81C7-4C62-8005-F245E3C7FB58Q33649218-66871143-A49F-46BD-8B57-5BF65CB431F3Q33905693-4B28ABC4-0296-4E1C-BCD1-C32719E39585Q33934837-5B930CB4-D0F1-4C9F-96B0-53BF336D3142Q33954971-C59334D5-24F4-492C-A365-8547B20E0604Q34050026-D55EA168-51AC-4E04-90F2-864D9D563220Q34349416-0925C7A6-73A2-47BF-80AA-620A66F30EE6Q34352200-1867D367-66DD-4CA1-B711-1BAC8AE57719Q34647460-E8712799-E3D7-4629-893C-54B2A87B3933Q34647795-6797BA4E-66D6-4D24-ADD6-0C020353FD27Q35192806-CF260C2C-E8AA-479B-8B28-A922949BB0EFQ35562096-16B35012-A063-47B8-939D-856D7ACC973AQ35588653-8F06B8A3-1535-441C-B8CB-0643FE1B35D4Q35764548-64C2876C-0249-4337-B204-B4F352D8926BQ35799502-AB1A2716-FED5-4884-B458-1D194DB72E48Q35847354-942A39EA-8108-47CB-AB7B-8D6FE893BE57Q35854157-079A3072-95CA-4210-B480-35ED079CD0ACQ35854673-08310DAD-D7FD-4F99-B8C8-D6EAE78CAC80Q35860678-7726F95C-A27C-4776-A6FF-5CB488F9B52AQ36414593-538CF62B-0F3B-4E51-83A0-DC09BAB3089CQ36633110-09591EB6-6044-48D7-9923-2FB451FA9054Q36647028-F04DC7FF-4658-4561-98C3-CBBE5E15FFDFQ36649427-AF207B71-BF37-4523-870C-5079381077E3Q36650345-AE1E3CBA-4BBE-4C88-AB7C-EAEBDD094EB5Q36665942-0EF52998-56F0-416A-84F2-552005FF61E8Q36672223-C800E8BA-1F86-42E2-8CD1-9748AECFA453Q36695353-1187F0A1-07CA-4AF4-A102-76B144D1B9A6Q37255166-913F7075-8464-4FDC-889F-B568732927ACQ37689359-D39FD3CB-2AE2-4548-BAFE-196BB9805853Q39796556-435203DE-80A0-45CF-87D5-3E5899646C62Q39845330-F0B9F60A-BA1F-4D88-BD57-9020B39796BBQ40041446-1BF4E403-FE4F-49CC-BCB7-72CF5628BFF3Q40145447-36F18012-8FDB-43B7-8C37-E9736574E8EC
P2860
Human papillomavirus type 16 E6 increases the degradation rate of p53 in human keratinocytes
description
1992 nî lūn-bûn
@nan
1992 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Human papillomavirus type 16 E ...... of p53 in human keratinocytes
@ast
Human papillomavirus type 16 E ...... of p53 in human keratinocytes
@en
type
label
Human papillomavirus type 16 E ...... of p53 in human keratinocytes
@ast
Human papillomavirus type 16 E ...... of p53 in human keratinocytes
@en
prefLabel
Human papillomavirus type 16 E ...... of p53 in human keratinocytes
@ast
Human papillomavirus type 16 E ...... of p53 in human keratinocytes
@en
P2093
P2860
P1433
P1476
Human papillomavirus type 16 E ...... of p53 in human keratinocytes
@en
P2093
J T Schiller
N L Hubbert
S A Sedman
P2860
P304
P577
1992-10-01T00:00:00Z