IRF8 regulates B-cell lineage specification, commitment, and differentiation. - Wikidata - wikimedia - TriplyDB

IRF8 regulates B-cell lineage specification, commitment, and differentiation.

IRF8 regulates B-cell lineage specification, commitment, and differentiation.

http://www.wikidata.org/entity/Q36969752

about

The genetic association of variants in CD6, TNFRSF1A and IRF8 to multiple sclerosis: a multicenter case-control study Molecular control of monocyte development Interferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCOR Tif1γ regulates the TGF-β1 receptor and promotes physiological aging of hematopoietic stem cells Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy IRF8 regulates myeloid and B lymphoid lineage diversification Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma.Critical role of IRF-5 in regulation of B-cell differentiation.Molecular karyotypes of Hodgkin and Reed-Sternberg cells at disease onset reveal distinct copy number alterations in chemosensitive versus refractory Hodgkin lymphoma A reporter mouse reveals lineage-specific and heterogeneous expression of IRF8 during lymphoid and myeloid cell differentiation.Hierarchical differentiation of myeloid progenitors is encoded in the transcription factor network Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development IRF8 governs expression of genes involved in innate and adaptive immunity in human and mouse germinal center B cells.Epigenomics of macrophages.Tagging single nucleotide polymorphisms in the IRF1 and IRF8 genes and tuberculosis susceptibility The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.Interleukin 27 induces the expression of complement factor H (CFH) in the retina.The EBV Latent Antigen 3C Inhibits Apoptosis through Targeted Regulation of Interferon Regulatory Factors 4 and 8.Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria.Transcriptome analysis of the interferon-signature defining the autoimmune process of Sjögren's syndrome Differential requirement for irf8 in formation of embryonic and adult macrophages in zebrafish.Avian pathogenic Escherichia coli (APEC) infection alters bone marrow transcriptome in chickens.IRF-8 extinguishes neutrophil production and promotes dendritic cell lineage commitment in both myeloid and lymphoid mouse progenitors Dual Function of the IRF8 Transcription Factor in Autoimmune Uveitis: Loss of IRF8 in T Cells Exacerbates Uveitis, Whereas Irf8 Deletion in the Retina Confers Protection Expression of essential B cell development genes in horses with common variable immunodeficiency.Loss of IRF8 Inhibits the Growth of Diffuse Large B-cell Lymphoma Interferon Regulator Factor 8 (IRF8) Limits Ocular Pathology during HSV-1 Infection by Restraining the Activation and Expansion of CD8+ T Cells.Bone marrow transcriptome and epigenome profiles of equine common variable immunodeficiency patients unveil block of B lymphocyte differentiation.IFN regulatory factor 8 restricts the size of the marginal zone and follicular B cell pools.The Blk pathway functions as a tumor suppressor in chronic myeloid leukemia stem cells.Interferon regulatory factor 8 integrates T-cell receptor and cytokine-signaling pathways and drives effector differentiation of CD8 T cells The interferon regulatory factors as novel potential targets in the treatment of cardiovascular diseases.C/EBPα is required for development of dendritic cell progenitors.The Interferon-Signature of Sjögren's Syndrome: How Unique Biomarkers Can Identify Underlying Inflammatory and Immunopathological Mechanisms of Specific Diseases miR-142-3p regulates the formation and differentiation of hematopoietic stem cells in vertebrates.IFN regulatory factor 8 regulates MDM2 in germinal center B cells.A role for IRF8 in B cell anergy.Mysm1 is required for interferon regulatory factor expression in maintaining HSC quiescence and thymocyte development.IRF8 suppresses pathological cardiac remodelling by inhibiting calcineurin signalling.Transient Cannabinoid Receptor 2 Blockade during Immunization Heightens Intensity and Breadth of Antigen-specific Antibody Responses in Young and Aged mice.

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P2860

IRF8 regulates B-cell lineage specification, commitment, and differentiation.

http://www.wikidata.org/entity/Q36969752

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

@zh-hk

2008年論文

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2008年論文

@zh-tw

2008年论文

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2008年论文

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2008年论文

@zh-cn

name

IRF8 regulates B-cell lineage specification, commitment, and differentiation.

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type

label

IRF8 regulates B-cell lineage specification, commitment, and differentiation.

@en

prefLabel

IRF8 regulates B-cell lineage specification, commitment, and differentiation.

@en

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BLOOD-2008-01-129049

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IRF8 regulates B-cell lineage specification, commitment, and differentiation.

@en

P2093

Chang Hoon Lee

http://www.w3.org/2001/XMLSchema#string

Chenfeng Qi

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Hongsheng Wang

http://www.w3.org/2001/XMLSchema#string

Jianxun Feng

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Prafullakumar Tailor

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Sadia Abbasi

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Toru Atsumi

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P2860

Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene

ICSBP/IRF-8: its regulatory roles in the development of myeloid cells

Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte-specific gene expression

Functional domain analysis of interferon consensus sequence binding protein (ICSBP) and its association with interferon regulatory factors

ICSBP/IRF-8 differentially regulates antigen uptake during dendritic-cell development and affects antigen presentation to CD4+ T cells

Essential role for ICSBP in the in vivo development of murine CD8alpha + dendritic cells

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

An interferon gamma-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes

Potential autoregulation of transcription factor PU.1 by an upstream regulatory element

Knockdown of Pu.1 by small interfering RNA in CD34+ embryoid body cells derived from mouse ES cells turns cell fate determination to pro-B cells.

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4028-4038

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10.1182/BLOOD-2008-01-129049

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10

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112

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Herbert C. Morse

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2008-09-17T00:00:00Z

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23264802

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18799728

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2581985

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