Relationship of amplified dihydrofolate reductase genes to double minute chromosomes in unstably resistant mouse fibroblast cell lines.
about
Evolution of nuclear ribosomal RNAs in kinetoplastid protozoa: perspectives on the age and origins of parasitismEvolution of the genus Leishmania as revealed by comparisons of nuclear DNA restriction fragment patternsRetroviral transduction of oncogenic sequences involves viral DNA instead of RNA.Toxicity of folic acid analogs in cultured human cells: a microtiter assay for the analysis of drug competition.Toward a better understanding of methotrexate.Resistance to cytostatic drugs at the cellular level.A study of chromosomal changes associated with amplified dihydrofolate reductase genes in rat hepatoma cells and their dedifferentiated variantsIsolation of genomic DNA controlling mouse melanoma antigen defined by monoclonal antibody.Amplification of the 11q13 region in human carcinoma cell lines: a mechanistic view.Introduction of YACs containing a putative mammalian replication origin into mammalian cells can generate structures that replicate autonomously.Formation of an inverted duplication can be an initial step in gene amplification.Unstable expression and amplification of a transfected oncogene in confluent and subconfluent cells.Murine dihydrofolate reductase transcripts through the cell cycle.Construction and use of a dominant, selectable marker: a Harvey sarcoma virus-dihydrofolate reductase chimeraEvolution of chromosomal regions containing transfected and amplified dihydrofolate reductase sequences.Enhancement of methotrexate resistance and dihydrofolate reductase gene amplification by treatment of mouse 3T6 cells with hydroxyureaCo-amplification of double minute chromosomes, multiple drug resistance, and cell surface P-glycoprotein in DNA-mediated transformants of mouse cells.Amplification and expression of human alpha-globin genes in Chinese hamster ovary cells.Amplification and loss of dihydrofolate reductase genes in a Chinese hamster ovary cell lineLoss and stabilization of amplified dihydrofolate reductase genes in mouse sarcoma S-180 cell lines.Construction of a modular dihydrofolate reductase cDNA gene: analysis of signals utilized for efficient expressionGrowth-dependent expression of dihydrofolate reductase mRNA from modular cDNA genes.Amplification of an alternate transporter gene suppresses the avirulent phenotype of glucose transporter null mutants in Leishmania mexicana.Specific DNA sequence amplification in human neuroblastoma cellsLoss of unstably amplified dihydrofolate reductase genes from mouse cells is greatly accelerated by hydroxyureaOverproduction of a bifunctional thymidylate synthetase-dihydrofolate reductase and DNA amplification in methotrexate-resistant Leishmania tropica.Mathematical modeling as a tool for planning anticancer therapy.Ultrastructural features of minute chromosomes in a methotrexate-resistant mouse 3T3 cell lineOpposite-strand RNAs from the 5' flanking region of the mouse dihydrofolate reductase gene.Detection and mapping of homologous, repeated and amplified DNA sequences by DNA renaturation in agarose gels.Circular DNA of 3T6R50 double minute chromosomes.Amplification and expression of a cellular oncogene (c-myc) in human gastric adenocarcinoma cells.Localization of a bidirectional DNA replication origin in the native locus and in episomally amplified murine adenosine deaminase loci.Mathematical models of gene amplification with applications to cellular drug resistance and tumorigenicity.Identification of transgene integration loci of different highly expressing recombinant CHO cell lines by FISH.Drug-induced loss of unstably amplified genes.Expression of phenotypic traits following modulation of colchicine resistance in J774.2 cells.Transcription factor Sp1 recognizes a DNA sequence in the mouse dihydrofolate reductase promoter.A clonal derivative of tunicamycin-resistant Chinese hamster ovary cells with increased N-acetylglucosamine-phosphate transferase activity has altered asparagine-linked glycosylation.Time-continuous branching walk models of unstable gene amplification.
P2860
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P2860
Relationship of amplified dihydrofolate reductase genes to double minute chromosomes in unstably resistant mouse fibroblast cell lines.
description
1981 nî lūn-bûn
@nan
1981年の論文
@ja
1981年論文
@yue
1981年論文
@zh-hant
1981年論文
@zh-hk
1981年論文
@zh-mo
1981年論文
@zh-tw
1981年论文
@wuu
1981年论文
@zh
1981年论文
@zh-cn
name
Relationship of amplified dihy ...... t mouse fibroblast cell lines.
@en
type
label
Relationship of amplified dihy ...... t mouse fibroblast cell lines.
@en
prefLabel
Relationship of amplified dihy ...... t mouse fibroblast cell lines.
@en
P2093
P2860
P356
P1476
Relationship of amplified dihy ...... t mouse fibroblast cell lines.
@en
P2093
R T Schimke
S M Beverley
P2860
P304
P356
10.1128/MCB.1.12.1077
P407
P577
1981-12-01T00:00:00Z