Changes in RNA polymerase II progression influence somatic hypermutation of Ig-related genes by AID - Wikidata - wikimedia - TriplyDB

Changes in RNA polymerase II progression influence somatic hypermutation of Ig-related genes by AID

Changes in RNA polymerase II progression influence somatic hypermutation of Ig-related genes by AID

http://www.wikidata.org/entity/Q36973654

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IgH chain class switch recombination: mechanism and regulation RNA Exosome Regulates AID DNA Mutator Activity in the B Cell Genome Variations in brain DNA Generation and repair of AID-initiated DNA lesions in B lymphocytes.Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.A source of the single-stranded DNA substrate for activation-induced deaminase during somatic hypermutation.Spt5 accumulation at variable genes distinguishes somatic hypermutation in germinal center B cells from ex vivo-activated cells.Targeting of somatic hypermutation by immunoglobulin enhancer and enhancer-like sequences.Regulating infidelity: RNA-mediated recruitment of AID to DNA during class switch recombination Lingering Questions about Enhancer RNA and Enhancer Transcription-Coupled Genomic Instability.AID Biology: A pathological and clinical perspective.Integrity of immunoglobulin variable regions is supported by GANP during AID-induced somatic hypermutation in germinal center B cells.

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Changes in RNA polymerase II progression influence somatic hypermutation of Ig-related genes by AID

http://www.wikidata.org/entity/Q36973654

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2013 nî lūn-bûn

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2013年の論文

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Changes in RNA polymerase II p ...... ion of Ig-related genes by AID

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Changes in RNA polymerase II p ...... ion of Ig-related genes by AID

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Changes in RNA polymerase II p ...... ion of Ig-related genes by AID

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Journal of Experimental Medicine

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Changes in RNA polymerase II p ...... ion of Ig-related genes by AID

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Prashant Kodgire

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Priyanka Mukkawar

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Sarayu Ratnam

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Terence E Martin

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Ursula Storb

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P2860

The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

Activation-induced cytidine deaminase initiates immunoglobulin gene conversion and hypermutation by a common intermediate

A new mathematical model for relative quantification in real-time RT-PCR

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

Multiple transcript cleavage precedes polymerase release in termination by RNA polymerase II

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

Somatic hypermutation and class switch recombination in Msh6(-/-)Ung(-/-) double-knockout mice

Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation

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scholarly article

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10.1084/JEM.20121523

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7

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210

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3698518

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