TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop.
about
Glucocerebrosidase is shaking up the synucleinopathiesIntegrated physiology and systems biology of PPARαThe crucial impact of lysosomes in aging and longevityEthanol-induced oxidant stress modulates hepatic autophagy and proteasome activityAutophagy in polyglutamine disease: Imposing order on disorder or contributing to the chaos?Cell-Autonomous and Non-Cell-Autonomous Regulation of a Feeding State-Dependent Chemoreceptor Gene via MEF-2 and bHLH Transcription FactorsTime course decomposition of cell heterogeneity in TFEB signaling states reveals homeostatic mechanisms restricting the magnitude and duration of TFEB responses to mTOR activity modulation.TFEB at a glanceGuidelines for monitoring autophagy in Caenorhabditis elegansTranscriptional and epigenetic regulation of autophagy in agingBeyond indigestion: emerging roles for lysosome-based signaling in human diseaseEssential role for autophagy in life span extensionRole of farnesoid X receptor and bile acids in alcoholic liver diseaseAmbroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cellsAn Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host DefenseRegulation of the transcription factor EB-PGC1α axis by beclin-1 controls mitochondrial quality and cardiomyocyte death under stressLysosome size, motility and stress response regulated by fronto-temporal dementia modifier TMEM106BLAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon diseaseExploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis.ATGL Promotes Autophagy/Lipophagy via SIRT1 to Control Hepatic Lipid Droplet Catabolism.TFE3 regulates whole-body energy metabolism in cooperation with TFEB.Lysosomal adaptation: how the lysosome responds to external cuesMetabolomic analysis shows differential hepatic effects of T2 and T3 in rats after short-term feeding with high fat diet.Novel roles for the MiTF/TFE family of transcription factors in organelle biogenesis, nutrient sensing, and energy homeostasisThe phytoestrogen genistein modulates lysosomal metabolism and transcription factor EB (TFEB) activationRapamycin attenuated cardiac hypertrophy induced by isoproterenol and maintained energy homeostasis via inhibiting NF-κB activation.Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesisRag GTPases are cardioprotective by regulating lysosomal function.Innate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genesEndocytosis, signaling, and beyondmTOR and lysosome regulation.Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelaeLongitudinal follow-up of autophagy and inflammation in brain of APPswePS1dE9 transgenic miceLiver autophagy in anorexia nervosa and acute liver injuryAutophagy and non-alcoholic fatty liver disease.Signals from the lysosome: a control centre for cellular clearance and energy metabolism.Lysosomal acid lipase: at the crossroads of normal and atherogenic cholesterol metabolismEIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibitionDefective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: prevention by correcting lysosomal proteolytic deficits.Lysosome: regulator of lipid degradation pathways.
P2860
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P2860
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop.
@en
type
label
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop.
@en
prefLabel
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop.
@en
P2093
P2860
P50
P356
P1433
P1476
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop.
@en
P2093
Amanda C Wollenberg
Donna Palmer
Francesco Vetrini
Lawrence Chan
Pradip K Saha
Tiemo Jürgen Klisch
Tuong Huynh
P2507
P2860
P2888
P304
P356
10.1038/NCB2718
P50
P577
2013-04-21T00:00:00Z