REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma - Wikidata - wikimedia - TriplyDB

REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

http://www.wikidata.org/entity/Q36987393

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Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal KCTD5, a putative substrate adaptor for cullin3 ubiquitin ligases Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway Biological background of pediatric medulloblastoma and ependymoma: a review from a translational research perspective Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy Context-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapy Pentameric Assembly of Potassium Channel Tetramerization Domain-Containing Protein 5 Cerebellum development and medulloblastoma Structure-activity relationships and cancer-cell selective toxicity of novel inhibitors of glioma-associated oncogene homologue 1 (Gli1) mediated transcription.Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma.KCTD11 inhibits growth and metastasis of hepatocellular carcinoma through activating Hippo signaling Targeting Hedgehog--a cancer stem cell pathway Novel mutation in potassium channel related gene KCTD7 and progressive myoclonic epilepsy.The Gli code: an information nexus regulating cell fate, stemness and cancer.Rapid diagnosis of medulloblastoma molecular subgroups.Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells.Deregulated proliferation and differentiation in brain tumors.Hedgehog signaling promotes medulloblastoma survival via Bc/II Cullin3-BTB interface: a novel target for stapled peptides Cullin 3 Recognition Is Not a Universal Property among KCTD Proteins.Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists.Bax deficiency prolongs cerebellar neurogenesis, accelerates medulloblastoma formation and paradoxically increases both malignancy and differentiation.Signification of Hypermethylated in Cancer 1 (HIC1) as Tumor Suppressor Gene in Tumor Progression.An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma Targeting stem cells in brain tumors.Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma.KCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway.Implications of hedgehog signaling antagonists for cancer therapy.New developments in medulloblastoma treatment: the potential of a cyclopamine-lovastatin combination.HIC1 (Hypermethylated in Cancer 1) epigenetic silencing in tumors Molecular pathways: the role of primary cilia in cancer progression and therapeutics with a focus on Hedgehog signaling.The coactivator CRTC1 promotes cell proliferation and transformation via AP-1 GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein.Medulloblastoma stem cells.Hypoxia triggers hedgehog-mediated tumor-stromal interactions in pancreatic cancer.Just say no to ATOH: how HIC1 methylation might predispose medulloblastoma to lineage addiction.Hedgehog-Gli signaling pathway inhibitors as anticancer agents.Negative regulation of Hedgehog signaling by liver X receptors.The KCTD family of proteins: structure, function, disease relevance.Epigenetics in cancer stem cells.

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REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

http://www.wikidata.org/entity/Q36987393

description

2004 nî lūn-bûn

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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2004年论文

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2004年论文

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name

REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

@en

type

label

REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

@en

prefLabel

REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

@en

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P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

@en

P2093

Alberto Gulino

http://www.w3.org/2001/XMLSchema#string

Andrea Modesti

http://www.w3.org/2001/XMLSchema#string

Beatrice Argenti

http://www.w3.org/2001/XMLSchema#string

Claudia Mincione

http://www.w3.org/2001/XMLSchema#string

Edoardo Alesse

http://www.w3.org/2001/XMLSchema#string

Isabella Screpanti

http://www.w3.org/2001/XMLSchema#string

Laura Masuelli

http://www.w3.org/2001/XMLSchema#string

Lucia Di Marcotullio

http://www.w3.org/2001/XMLSchema#string

Maddalena Napolitano

http://www.w3.org/2001/XMLSchema#string

Marella Maroder

http://www.w3.org/2001/XMLSchema#string

P2860

Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1

The POZ domain: a conserved protein-protein interaction motif

Gli proteins encode context-dependent positive and negative functions: implications for development and disease

Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling

Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum

Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation

Characterization of the physical interaction of Gli proteins with SUFU proteins

Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1

REN: a novel, developmentally regulated gene that promotes neural cell differentiation

Sonic hedgehog regulates the growth and patterning of the cerebellum

P304

10833-10838

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10.1073/PNAS.0400690101

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P407

P433

29

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P478

101

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Elisabetta Ferretti

Enrico De Smaele

Francesca Zazzeroni

P577

2004-07-12T00:00:00Z

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P5875

8459017

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P698

15249678

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P921

medulloblastoma

P932

490020

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