REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma
about
Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signalKCTD5, a putative substrate adaptor for cullin3 ubiquitin ligasesArsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathwayBiological background of pediatric medulloblastoma and ependymoma: a review from a translational research perspectiveCooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapyContext-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapyPentameric Assembly of Potassium Channel Tetramerization Domain-Containing Protein 5Cerebellum development and medulloblastomaStructure-activity relationships and cancer-cell selective toxicity of novel inhibitors of glioma-associated oncogene homologue 1 (Gli1) mediated transcription.Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma.KCTD11 inhibits growth and metastasis of hepatocellular carcinoma through activating Hippo signalingTargeting Hedgehog--a cancer stem cell pathwayNovel mutation in potassium channel related gene KCTD7 and progressive myoclonic epilepsy.The Gli code: an information nexus regulating cell fate, stemness and cancer.Rapid diagnosis of medulloblastoma molecular subgroups.Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells.Deregulated proliferation and differentiation in brain tumors.Hedgehog signaling promotes medulloblastoma survival via Bc/IICullin3-BTB interface: a novel target for stapled peptidesCullin 3 Recognition Is Not a Universal Property among KCTD Proteins.Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists.Bax deficiency prolongs cerebellar neurogenesis, accelerates medulloblastoma formation and paradoxically increases both malignancy and differentiation.Signification of Hypermethylated in Cancer 1 (HIC1) as Tumor Suppressor Gene in Tumor Progression.An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastomaTargeting stem cells in brain tumors.Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma.KCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway.Implications of hedgehog signaling antagonists for cancer therapy.New developments in medulloblastoma treatment: the potential of a cyclopamine-lovastatin combination.HIC1 (Hypermethylated in Cancer 1) epigenetic silencing in tumorsMolecular pathways: the role of primary cilia in cancer progression and therapeutics with a focus on Hedgehog signaling.The coactivator CRTC1 promotes cell proliferation and transformation via AP-1GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein.Medulloblastoma stem cells.Hypoxia triggers hedgehog-mediated tumor-stromal interactions in pancreatic cancer.Just say no to ATOH: how HIC1 methylation might predispose medulloblastoma to lineage addiction.Hedgehog-Gli signaling pathway inhibitors as anticancer agents.Negative regulation of Hedgehog signaling by liver X receptors.The KCTD family of proteins: structure, function, disease relevance.Epigenetics in cancer stem cells.
P2860
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P2860
REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma
@en
type
label
REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma
@en
prefLabel
REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma
@en
P2093
P2860
P50
P356
P1476
REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma
@en
P2093
Alberto Gulino
Andrea Modesti
Beatrice Argenti
Claudia Mincione
Edoardo Alesse
Isabella Screpanti
Laura Masuelli
Lucia Di Marcotullio
Maddalena Napolitano
Marella Maroder
P2860
P304
10833-10838
P356
10.1073/PNAS.0400690101
P407
P577
2004-07-12T00:00:00Z