The Gli code: an information nexus regulating cell fate, stemness and cancer.
about
The CK1 Family: Contribution to Cellular Stress Response and Its Role in CarcinogenesisDual function of UNC-51-like kinase 3 (Ulk3) in the Sonic hedgehog signaling pathwayMED12 mutations link intellectual disability syndromes with dysregulated GLI3-dependent Sonic Hedgehog signalingGli-similar (Glis) Krüppel-like zinc finger proteins: insights into their physiological functions and critical roles in neonatal diabetes and cystic renal diseaseGlioma Stem Cells and Their Microenvironments: Providers of Challenging Therapeutic TargetsThe Sum1/Ndt80 transcriptional switch and commitment to meiosis in Saccharomyces cerevisiaeHedgehog signaling inhibitors as anti-cancer agents in osteosarcomaBrain tumor stem cells: Molecular characteristics and their impact on therapyContext-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapySOX9 inhibits β-TrCP-mediated protein degradation to promote nuclear GLI1 expression and cancer stem cell properties.Hedgehog signaling and the Gli code in stem cells, cancer, and metastasesSustained proliferation in cancer: Mechanisms and novel therapeutic targetsComputational prediction and experimental verification of new MAP kinase docking sites and substrates including Gli transcription factorsA novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse modelHedgehog signaling pathway is active in GBM with GLI1 mRNA expression showing a single continuous distribution rather than discrete high/low clustersDYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistanceTargeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration.Hedgehog-dependent proliferation drives modular growth during morphogenesis of a dermal boneGenomic organization and phylogenetic utility of deer mouse (Peromyscus maniculatus) lymphotoxin-alpha and lymphotoxin-beta.Structure-activity relationships and cancer-cell selective toxicity of novel inhibitors of glioma-associated oncogene homologue 1 (Gli1) mediated transcription.GLI1 is a central mediator of EWS/FLI1 signaling in Ewing tumors.Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb developmentEffects of inhibition of hedgehog signaling on cell growth and migration of uveal melanoma cells.PDGFRα up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation.Activation of Hedgehog signaling by the environmental toxicant arsenic may contribute to the etiology of arsenic-induced tumors.cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells.Inhibition of hedgehog signaling decreases proliferation and clonogenicity of human mesenchymal stem cells.ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancerTargeting Hedgehog--a cancer stem cell pathwayGli1 promotes cell survival and is predictive of a poor outcome in ERalpha-negative breast cancer.Gene expression profiling of the hedgehog signaling pathway in human meningiomas.Potential therapeutic implications of cancer stem cells in glioblastomaThe transcriptional activity of Gli1 is negatively regulated by AMPK through Hedgehog partial agonism in hepatocellular carcinoma.SUMOylation by Pias1 regulates the activity of the Hedgehog dependent Gli transcription factorsEctodermal influx and cell hypertrophy provide early growth for all murine mammary rudiments, and are differentially regulated among them by Gli3.Delta-cell-specific expression of hedgehog pathway Ptch1 receptor in murine and human endocrine pancreas.SOX9 governs differentiation stage-specific gene expression in growth plate chondrocytes via direct concomitant transactivation and repression.NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53.Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies.Downregulation of the gli transcription factors regulator Kif7 facilitates cell survival and migration of choriocarcinoma cells.
P2860
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P2860
The Gli code: an information nexus regulating cell fate, stemness and cancer.
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The Gli code: an information nexus regulating cell fate, stemness and cancer.
@ast
The Gli code: an information nexus regulating cell fate, stemness and cancer.
@en
The Gli code: an information nexus regulating cell fate, stemness and cancer.
@nl
type
label
The Gli code: an information nexus regulating cell fate, stemness and cancer.
@ast
The Gli code: an information nexus regulating cell fate, stemness and cancer.
@en
The Gli code: an information nexus regulating cell fate, stemness and cancer.
@nl
prefLabel
The Gli code: an information nexus regulating cell fate, stemness and cancer.
@ast
The Gli code: an information nexus regulating cell fate, stemness and cancer.
@en
The Gli code: an information nexus regulating cell fate, stemness and cancer.
@nl
P2860
P1476
The Gli code: an information nexus regulating cell fate, stemness and cancer
@en
P2093
Ariel Ruiz i Altaba
P2860
P304
P356
10.1016/J.TCB.2007.06.007
P577
2007-09-12T00:00:00Z