Expression of the alpha-1-antitrypsin gene in mononuclear phagocytes of normal and alpha-1-antitrypsin-deficient individuals
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Expression of the secretory leukoprotease inhibitor gene in epithelial cellsThe Role of Serine Proteases and Antiproteases in the Cystic Fibrosis LungAlpha-1-antitrypsin deficiencyADD66, a gene involved in the endoplasmic reticulum-associated degradation of alpha-1-antitrypsin-Z in yeast, facilitates proteasome activity and assembly.Oncostatin M is a potent stimulator of alpha1-antitrypsin secretion in lung epithelial cells: modulation by transforming growth factor-beta and interferon-gammaA novel model and molecular therapy for Z alpha-1 antitrypsin deficiency.Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy.The role of bronchial epithelial cells in the pathogenesis of COPD in Z-alpha-1 antitrypsin deficiencyCytosolic, autocrine alpha-1 proteinase inhibitor (A1PI) inhibits caspase-1 and blocks IL-1β dependent cytokine release in monocytes.Multiple tissues express alpha 1-antitrypsin in transgenic mice and man.Secretory products of macrophages.Alpha 1-antitrypsin deficiency caused by the alpha 1-antitrypsin Nullmattawa gene. An insertion mutation rendering the alpha 1-antitrypsin gene incapable of producing alpha 1-antitrypsinSynthesis of stress proteins is increased in individuals with homozygous PiZZ alpha 1-antitrypsin deficiency and liver diseaseProduction of glycosylated physiologically "normal" human alpha 1-antitrypsin by mouse fibroblasts modified by insertion of a human alpha 1-antitrypsin cDNA using a retroviral vector.Emphysema associated with complete absence of alpha 1- antitrypsin in serum and the homozygous inheritance [corrected] of a stop codon in an alpha 1-antitrypsin-coding exon.Tracheobronchial protease inhibitors, body surface area burns, and mortality in smoke inhalation.Z-type alpha 1-antitrypsin is less competent than M1-type alpha 1-antitrypsin as an inhibitor of neutrophil elastase.Modulation of fibronectin gene expression in human mononuclear phagocytesConstitutive and modulated expression of the human alpha 1 antitrypsin gene. Different transcriptional initiation sites used in three different cell types.Polymers of Z alpha1-antitrypsin co-localize with neutrophils in emphysematous alveoli and are chemotactic in vivoAlpha1-antitrypsin deficiency. 4: Molecular pathophysiologyRisk factors for emphysema. Cigarette smoking is associated with a reduction in the association rate constant of lung alpha 1-antitrypsin for neutrophil elastase.Biased accumulation of T lymphocytes with "memory"-type CD45 leukocyte common antigen gene expression on the epithelial surface of the human lungThe selective advantage of alpha1-antitrypsin deficiency.The emerging importance of autophagy in pulmonary diseases.Molecular basis of alpha 1-antitrypsin deficiency and emphysema associated with the alpha 1-antitrypsin Mmineral springs allele.Alpha-1 antitrypsin gene exon use in stimulated lymphocytes.The effect of α1-antitrypsin deficiency combined with increased bacterial loads on chronic obstructive pulmonary disease pharmacotherapy: A prospective, parallel, controlled pilot studyAutophagy: a critical regulator of cellular metabolism and homeostasis.Dexamethasone-mediated repression of MUC5AC gene expression in human lung epithelial cells.Gene Therapy for Alpha-1 Antitrypsin Deficiency Lung Disease.Antiproteases as therapeutics to target inflammation in cystic fibrosis.Oncostatin M induced alpha1-antitrypsin (AAT) gene expression in Hep G2 cells is mediated by a 3' enhancer.Elastase regulates the synthesis of its inhibitor, alpha 1-proteinase inhibitor, and exaggerates the defect in homozygous PiZZ alpha 1 PI deficiency.Low density lipoprotein catabolism is enhanced by the cleaved form of alpha-1-antitrypsin.Expression of HLA class II genes in alveolar macrophages of patients with sarcoidosis.Differential recognition of alpha 1-antitrypsin-elastase and alpha 1-antichymotrypsin-cathepsin G complexes by the low density lipoprotein receptor-related protein.Pulmonary cell biology.Polymers of alpha(1)-antitrypsin are chemotactic for human neutrophils: a new paradigm for the pathogenesis of emphysema.Polymorphism of alpha-1-antitrypsin in hematological malignancies.
P2860
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P2860
Expression of the alpha-1-antitrypsin gene in mononuclear phagocytes of normal and alpha-1-antitrypsin-deficient individuals
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Expression of the alpha-1-anti ...... itrypsin-deficient individuals
@en
type
label
Expression of the alpha-1-anti ...... itrypsin-deficient individuals
@en
prefLabel
Expression of the alpha-1-anti ...... itrypsin-deficient individuals
@en
P2093
P2860
P356
P1476
Expression of the alpha-1-anti ...... itrypsin-deficient individuals
@en
P2093
Chytil-Weir A
Courtney M
Crystal RG
Martinet Y
P2860
P304
P356
10.1172/JCI112524
P407
P577
1986-06-01T00:00:00Z