AKT alters genome-wide estrogen receptor alpha binding and impacts estrogen signaling in breast cancer. - Wikidata - wikimedia - TriplyDB

AKT alters genome-wide estrogen receptor alpha binding and impacts estrogen signaling in breast cancer.

AKT alters genome-wide estrogen receptor alpha binding and impacts estrogen signaling in breast cancer.

http://www.wikidata.org/entity/Q36994934

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H3K27 demethylation by JMJD3 at a poised enhancer of anti-apoptotic gene BCL2 determines ERα ligand dependency Pioneer transcription factors: establishing competence for gene expression Estrogen receptor alpha controls a gene network in luminal-like breast cancer cells comprising multiple transcription factors and microRNAs Prognosis of hormone-dependent breast cancers: implications of the presence of dysfunctional transcriptional networks activated by insulin via the immune transcription factor T-bet Nuclear Receptor Signaling Atlas: Opening Access to the Biology of Nuclear Receptor Signaling Pathways Cistrome plasticity and mechanisms of cistrome reprogramming The synergistic effect of Mig-6 and Pten ablation on endometrial cancer development and progression.Signal transducers and activators of transcription-1 (STAT1) regulates microRNA transcription in interferon gamma-stimulated HeLa cells.SLUG/SNAI2 and tumor necrosis factor generate breast cells with CD44+/CD24- phenotype.Effectiveness and molecular interactions of the clinically active mTORC1 inhibitor everolimus in combination with tamoxifen or letrozole in vitro and in vivo.Subcellular localization of activated AKT in estrogen receptor- and progesterone receptor-expressing breast cancers: potential clinical implications The IGF pathway regulates ERα through a S6K1-dependent mechanism in breast cancer cells.Interplay between estrogen receptor and AKT in estradiol-induced alternative splicing FOXA1 in breast cancer.Steroid hormone modulation of RET through two estrogen responsive enhancers in breast cancer.Lrig1 is an estrogen-regulated growth suppressor and correlates with longer relapse-free survival in ERα-positive breast cancer.Cellular reprogramming by the conjoint action of ERα, FOXA1, and GATA3 to a ligand-inducible growth state.More on FOX News: FOXA1 on the horizon of estrogen receptor function and endocrine response.Influence of AKT on progesterone action in endometrial diseases.Molecular mechanisms regulating the hormone sensitivity of breast cancer.Estrogenic regulation of S6K1 expression creates a positive regulatory loop in control of breast cancer cell proliferation The rearranged during transfection/papillary thyroid carcinoma tyrosine kinase is an estrogen-dependent gene required for the growth of estrogen receptor positive breast cancer cells.Bromodomain protein BRD4 is required for estrogen receptor-dependent enhancer activation and gene transcription Biology and therapeutic potential of PI3K signaling in ER+/HER2-negative breast cancer.Estradiol-regulated microRNAs control estradiol response in breast cancer cells.Expression of a phosphorylated p130(Cas) substrate domain attenuates the phosphatidylinositol 3-kinase/Akt survival pathway in tamoxifen resistant breast cancer cells.SIRT1 represses estrogen-signaling, ligand-independent ERα-mediated transcription, and cell proliferation in estrogen-responsive breast cells.Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance.Sex specific activation of the ERα axis of the mitochondrial UPR (UPRmt) in the G93A-SOD1 mouse model of familial ALS.From discovery of the CHOP axis and targeting ClpP to the identification of additional axes of the UPRmt driven by the estrogen receptor and SIRT3.Angiopoietin-2 mediates blood-brain barrier impairment and colonization of triple-negative breast cancer cells in brain.Liposomal trichostatin A: therapeutic potential in hormone-dependent and -independent breast cancer xenograft models.The mammalian target of rapamycin inhibitor everolimus (RAD001) in early breast cancer: results of a pre-operative study.Dependence receptor UNC5A restricts luminal to basal breast cancer plasticity and metastasis.Signaling pathways and steroid receptors modulating estrogen receptor α function in breast cancer

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P2860

AKT alters genome-wide estrogen receptor alpha binding and impacts estrogen signaling in breast cancer.

http://www.wikidata.org/entity/Q36994934

description

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2008年の論文

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2008年论文

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name

AKT alters genome-wide estroge ...... en signaling in breast cancer.

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AKT alters genome-wide estroge ...... en signaling in breast cancer.

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AKT alters genome-wide estroge ...... en signaling in breast cancer.

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Molecular and Cellular Biology

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AKT alters genome-wide estroge ...... gen signaling in breast cancer

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Guohua Wang

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Hitesh Appaiah

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Jason S Carroll

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Nikhil Luktuke

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Sunil Badve

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Tim R Geistlinger

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Yunlong Liu

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P2860

Functional synergy between the transcription factor Sp1 and the estrogen receptor

Heme regulates gene expression by triggering Crm1-dependent nuclear export of Bach1

The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex

E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop

Phosphorylation and regulation of Raf by Akt (protein kinase B)

Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance

TGIF2 interacts with histone deacetylase 1 and represses transcription

AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer

Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1

EpCAM is overexpressed in breast cancer and is a potential target for breast cancer gene therapy

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10.1128/MCB.00799-08

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Harikrishna Nakshatri

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18838536

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