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Targeting EZH2 in cancerAdenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profilingMediator kinase module and human tumorigenesisFibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implicationsCancer stem cell division: when the rules of asymmetry are brokenStructural variation discovery in the cancer genome using next generation sequencing: computational solutions and perspectivesSWI/SNF chromatin remodeling complexes and cancerCharacterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodiesDetection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinoma.NFIB regulates embryonic development of submandibular glandsPathways Affected in Adenoid Cystic CarcinomaNOTCH1 and SOX10 are Essential for Proliferation and Radiation Resistance of Cancer Stem-Like Cells in Adenoid Cystic Carcinoma.An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma.Adenoid cystic carcinoma: A review of recent advances, molecular targets, and clinical trials.Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinoma.Mutation signature of adenoid cystic carcinoma: evidence for transcriptional and epigenetic reprogrammingHotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands.ChromoHub V2: cancer genomics.Clinical application of genomic profiling to find druggable targets for adolescent and young adult (AYA) cancer patients with metastasis.Collection, integration and analysis of cancer genomic profiles: from data to insight.Mutations of Chromatin Structure Regulating Genes in Human Malignancies.Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA.The H3K27me3 demethylase UTX in normal development and disease.A phase 2 study of vorinostat in locally advanced, recurrent, or metastatic adenoid cystic carcinoma.Prediction of individualized therapeutic vulnerabilities in cancer from genomic profiles.Functional and therapeutic significance of EZH2 in urological cancersTriple-negative breast cancer: the importance of molecular and histologic subtyping, and recognition of low-grade variants.The Fibroblast Growth Factor signaling pathwayGenomic aberrations of MDM2, MDM4, FGFR1 and FGFR3 are associated with poor outcome in patients with salivary gland cancer.Sleeping Beauty mouse models identify candidate genes involved in gliomagenesis.Inhibition of mTOR reduce Stat3 and PAI related angiogenesis in salivary gland adenoid cystic carcinoma.Transcriptome meta-analysis of lung cancer reveals recurrent aberrations in NRG1 and Hippo pathway genes.Fatty Acid binding protein 7 is a molecular marker in adenoid cystic carcinoma of the salivary glands: implications for clinical significance.Notch signaling induces epithelial-mesenchymal transition to promote invasion and metastasis in adenoid cystic carcinoma.Signaling-mediated regulation of MicroRNA processingA unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets.Protein domain-level landscape of cancer-type-specific somatic mutations.High frequency of loss of PTEN expression in human solid salivary adenoid cystic carcinoma and its implication for targeted therapy.The effects of chromatin organization on variation in mutation rates in the genome.Uterine adenosarcomas are mesenchymal neoplasms.
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description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 19 May 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
The mutational landscape of adenoid cystic carcinoma
@en
The mutational landscape of adenoid cystic carcinoma.
@nl
type
label
The mutational landscape of adenoid cystic carcinoma
@en
The mutational landscape of adenoid cystic carcinoma.
@nl
prefLabel
The mutational landscape of adenoid cystic carcinoma
@en
The mutational landscape of adenoid cystic carcinoma.
@nl
P2093
P2860
P50
P356
P1433
P1476
The mutational landscape of adenoid cystic carcinoma
@en
P2093
Adriana Heguy
Agnes Viale
Allen S Ho
Benjamin E Gross
Benjamin J Raphael
Bhuvanesh Singh
C Rene Leemans
Chris Sander
Christine E Rice
David M Roy
P2860
P2888
P304
P356
10.1038/NG.2643
P407
P50
P577
2013-05-19T00:00:00Z