Palm mutants in DNA polymerases alpha and eta alter DNA replication fidelity and translesion activity.
about
The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conservedThe fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerasesExpression of human AID in yeast induces mutations in context similar to the context of somatic hypermutation at G-C pairs in immunoglobulin genesDNA polymerase delta in DNA replication and genome maintenanceCharacterization of a replicative DNA polymerase mutant with reduced fidelity and increased translesion synthesis capacityMismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase ε.RNA-templated DNA repairSensitivity to phosphonoacetic acid: a new phenotype to probe DNA polymerase delta in Saccharomyces cerevisiae.Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesisRole of single-stranded DNA in targeting REV1 to primer terminiDNA polymerases at the eukaryotic fork-20 years laterLagging-strand replication shapes the mutational landscape of the genomeGenetic instability in budding and fission yeast-sources and mechanismsEukaryotic genome instability in light of asymmetric DNA replicationThe high fidelity and unique error signature of human DNA polymerase epsilonINCURVATA2 encodes the catalytic subunit of DNA Polymerase alpha and interacts with genes involved in chromatin-mediated cellular memory in Arabidopsis thaliana.Effect of dehydroaltenusin-C12 derivative, a selective DNA polymerase alpha inhibitor, on DNA replication in cultured cells.A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in genomic instability.Participation of DNA polymerase zeta in replication of undamaged DNA in Saccharomyces cerevisiae.Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases.Engineering processive DNA polymerases with maximum benefit at minimum costEvidence for extrinsic exonucleolytic proofreading.Error Rate Comparison during Polymerase Chain Reaction by DNA PolymeraseDetection of ultra-rare mutations by next-generation sequencing.Differential correction of lagging-strand replication errors made by DNA polymerases {alpha} and {delta}Mismatch repair balances leading and lagging strand DNA replication fidelity.The mechanistic architecture of thermostable Pyrococcus furiosus family B DNA polymerase motif A and its interaction with the dNTP substrateA novel function of DNA polymerase zeta regulated by PCNA.Replication of ribonucleotide-containing DNA templates by yeast replicative polymerases.Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation.Balancing eukaryotic replication asymmetry with replication fidelity.Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing its own infidelityInefficient proofreading and biased error rates during inaccurate DNA synthesis by a mutant derivative of Saccharomyces cerevisiae DNA polymerase delta.Quantifying the contributions of base selectivity, proofreading and mismatch repair to nuclear DNA replication in Saccharomyces cerevisiae.Regulation of B family DNA polymerase fidelity by a conserved active site residue: characterization of M644W, M644L and M644F mutants of yeast DNA polymerase epsilon.DNA polymerase from temperate phage Bam35 is endowed with processive polymerization and abasic sites translesion synthesis capacity.Okazaki fragment maturation involves α-segment error editing by the mammalian FEN1/MutSα functional complex.Human Pol ε-dependent replication errors and the influence of mismatch repair on their correction.Escherichia coli UmuC active site mutants: effects on translesion DNA synthesis, mutagenesis and cell survival.Mutator alleles of yeast DNA polymerase zeta.
P2860
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P2860
Palm mutants in DNA polymerases alpha and eta alter DNA replication fidelity and translesion activity.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Palm mutants in DNA polymerase ...... lity and translesion activity.
@en
Palm mutants in DNA polymerase ...... lity and translesion activity.
@nl
type
label
Palm mutants in DNA polymerase ...... lity and translesion activity.
@en
Palm mutants in DNA polymerase ...... lity and translesion activity.
@nl
prefLabel
Palm mutants in DNA polymerase ...... lity and translesion activity.
@en
Palm mutants in DNA polymerase ...... lity and translesion activity.
@nl
P2093
P2860
P1476
Palm mutants in DNA polymerase ...... lity and translesion activity.
@en
P2093
Atsuko Niimi
Chikahide Masutani
Eric T Kool
Fumio Hanaoka
Motoshi Suzuki
Shigenori Iwai
Shonen Yoshida
Siripan Limsirichaikul
Yukihiro Nishiyama
P2860
P304
P356
10.1128/MCB.24.7.2734-2746.2004
P407
P577
2004-04-01T00:00:00Z