Variation in chemical properties and antigenic determinants among type II heat-labile enterotoxins of Escherichia coli.
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Diarrheagenic Escherichia coliDiarrheagenic Escherichia coli.Cholera toxin toxicity does not require functional Arf6- and dynamin-dependent endocytic pathways.Mucosal adjuvant properties of mutant LT-IIa and LT-IIb enterotoxins that exhibit altered ganglioside-binding activities.Differential binding of Escherichia coli enterotoxins LT-IIa and LT-IIb and of cholera toxin elicits differences in apoptosis, proliferation, and activation of lymphoid cells.Binding to gangliosides containing N-acetylneuraminic acid is sufficient to mediate the immunomodulatory properties of the nontoxic mucosal adjuvant LT-IIb(T13I)Comparative analysis of the mucosal adjuvanticity of the type II heat-labile enterotoxins LT-IIa and LT-IIbRecombinant antigen-enterotoxin A2/B chimeric mucosal immunogens differentially enhance antibody responses and B7-dependent costimulation of CD4(+) T cells.Activation of Escherichia coli heat-labile enterotoxins by native and recombinant adenosine diphosphate-ribosylation factors, 20-kD guanine nucleotide-binding proteins.LT-IIc, a new member of the type II heat-labile enterotoxin family encoded by an Escherichia coli strain obtained from a nonmammalian host.LT-IIc, a new member of the type II heat-labile enterotoxin family, exhibits potent immunomodulatory properties that are different from those induced by LT-IIa or LT-IIb.Distinctive immunomodulatory and inflammatory properties of the Escherichia coli type II heat-labile enterotoxin LT-IIa and its B pentamer following intradermal administration.Initial studies of the structural signal for extracellular transport of cholera toxin and other proteins recognized by Vibrio cholerae.Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxinMutants of type II heat-labile enterotoxin LT-IIa with altered ganglioside-binding activities and diminished toxicity are potent mucosal adjuvants.In vitro induction of immunoglobulin A (IgA)- and IgM-secreting plasma blasts by cholera toxin depends on T-cell help and is mediated by CD154 up-regulation and inhibition of gamma interferon synthesisCloning, nucleotide sequence, and hybridization studies of the type IIb heat-labile enterotoxin gene of Escherichia coliGanglioside structure dictates signal transduction by cholera toxin and association with caveolae-like membrane domains in polarized epithelia.Genetics of type IIa heat-labile enterotoxin of Escherichia coli: operon fusions, nucleotide sequence, and hybridization studies.Characterization of hybrid toxins produced in Escherichia coli by assembly of A and B polypeptides from type I and type II heat-labile enterotoxinsMolecular genetic analysis of ganglioside GD1b-binding activity of Escherichia coli type IIa heat-labile enterotoxin by use of random and site-directed mutagenesisVirulence properties of enterotoxigenic Escherichia coli O8: KX105 strains isolated from diarrheic piglets.Comparison of the carbohydrate-binding specificities of cholera toxin and Escherichia coli heat-labile enterotoxins LTh-I, LT-IIa, and LT-IIbType II heat-labile enterotoxin of Escherichia coli activates adenylate cyclase in human fibroblasts by ADP ribosylationShiga and Shiga-like toxinsAnimal Enterotoxigenic Escherichia coli.Purification and characterization of a Chinese hamster ovary cell elongation factor of Vibrio hollisae.Binding of class II Escherichia coli enterotoxins to mouse Y1 and intestinal cells.Physicochemical and biological properties of purified Escherichia coli Shiga-like toxin II variant.Type II heat-labile enterotoxin-producing Escherichia coli isolated from animals and humans.
P2860
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P2860
Variation in chemical properties and antigenic determinants among type II heat-labile enterotoxins of Escherichia coli.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
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1986年學術文章
@zh-hant
name
Variation in chemical properti ...... erotoxins of Escherichia coli.
@en
Variation in chemical properti ...... erotoxins of Escherichia coli.
@nl
type
label
Variation in chemical properti ...... erotoxins of Escherichia coli.
@en
Variation in chemical properti ...... erotoxins of Escherichia coli.
@nl
prefLabel
Variation in chemical properti ...... erotoxins of Escherichia coli.
@en
Variation in chemical properti ...... erotoxins of Escherichia coli.
@nl
P2093
P2860
P1476
Variation in chemical properti ...... erotoxins of Escherichia coli.
@en
P2093
E M Twiddy
L R Trabulsi
R K Holmes
P2860
P304
P407
P577
1986-11-01T00:00:00Z