Regulation of cartilage-specific gene expression in human chondrocytes by SirT1 and nicotinamide phosphoribosyltransferase. - Wikidata - wikimedia - TriplyDB

Regulation of cartilage-specific gene expression in human chondrocytes by SirT1 and nicotinamide phosphoribosyltransferase.

Regulation of cartilage-specific gene expression in human chondrocytes by SirT1 and nicotinamide phosphoribosyltransferase.

http://www.wikidata.org/entity/Q37021544

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Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promoters Cellular ageing mechanisms in osteoarthritis Inflammation and intracellular metabolism: new targets in OA Epigenetic Regulation of Chondrocyte Catabolism and Anabolism in Osteoarthritis Emerging regulators of the inflammatory process in osteoarthritis The role of mammalian sirtuins in the regulation of metabolism, aging, and longevity Review: Metabolic Regulation of Inflammation in Osteoarthritis Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy Adipokines: Biomarkers for osteoarthritis?Sirtuin 1 enzymatic activity is required for cartilage homeostasis in vivo in a mouse model Sirtuin-1 (SIRT1) is required for promoting chondrogenic differentiation of mesenchymal stem cells.SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway.Cartilage repair using human embryonic stem cell-derived chondroprogenitors.Sirt1-deficient mice exhibit an altered cartilage phenotype Nicotinamide phosphoribosyltransferase is essential for interleukin-1beta-mediated dedifferentiation of articular chondrocytes via SIRT1 and extracellular signal-regulated kinase (ERK) complex signaling Tumor necrosis factor α-mediated cleavage and inactivation of SirT1 in human osteoarthritic chondrocytes Detecting cathepsin activity in human osteoarthritis via activity-based probes.Proteases involved in cartilage matrix degradation in osteoarthritis.Epigenetics and Osteoarthritis.75-kd sirtuin 1 blocks tumor necrosis factor α-mediated apoptosis in human osteoarthritic chondrocytes.Epigenomic and microRNA-mediated regulation in cartilage development, homeostasis, and osteoarthritis The effects of aging on the development of osteoarthritis.Expression of silent mating type information regulator 2 homolog 1 and its role in human intervertebral disc cell homeostasis.Epigenetic mechanisms underlying the aberrant catabolic and anabolic activities of osteoarthritic chondrocytes.Histone Deacetylases in Bone Development and Skeletal Disorders.Increased apoptotic chondrocytes in articular cartilage from adult heterozygous SirT1 mice.Role of LRF/Pokemon in lineage fate decisions.Chopping off the chondrocyte proteome.Acetylation reduces SOX9 nuclear entry and ACAN gene transactivation in human chondrocytes.Epigenetic and microRNA regulation during osteoarthritis development The NAD-Dependent Deacetylase Sirtuin-1 Regulates the Expression of Osteogenic Transcriptional Activator Runt-Related Transcription Factor 2 (Runx2) and Production of Matrix Metalloproteinase (MMP)-13 in Chondrocytes in Osteoarthritis.SIRT1 is a Highly Networked Protein That Mediates the Adaptation to Chronic Physiological Stress.SIRT1 inhibits apoptosis of degenerative human disc nucleus pulposus cells through activation of Akt pathway.Paracrine effects of human adipose-derived mesenchymal stem cells in inflammatory stress-induced senescence features of osteoarthritic chondrocytes NMNATs, evolutionarily conserved neuronal maintenance factors.The expression of SIRT1 in articular cartilage of patients with knee osteoarthritis and its correlation with disease severity.Small interfering RNA-mediated silencing of nicotinamide phosphoribosyltransferase (NAMPT) and lysosomal trafficking regulator (LYST) induce growth inhibition and apoptosis in human multiple myeloma cells: A preliminary study.Inflammation and epigenetic regulation in osteoarthritis.SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions Epigenetic modifications of interleukin-6 in synovial fibroblasts from osteoarthritis patients

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Regulation of cartilage-specific gene expression in human chondrocytes by SirT1 and nicotinamide phosphoribosyltransferase.

http://www.wikidata.org/entity/Q37021544

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 28 October 2008

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Regulation of cartilage-specif ...... ide phosphoribosyltransferase.

@en

Regulation of cartilage-specif ...... ide phosphoribosyltransferase.

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type

label

Regulation of cartilage-specif ...... ide phosphoribosyltransferase.

@en

Regulation of cartilage-specif ...... ide phosphoribosyltransferase.

@nl

prefLabel

Regulation of cartilage-specif ...... ide phosphoribosyltransferase.

@en

Regulation of cartilage-specif ...... ide phosphoribosyltransferase.

@nl

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Journal of Biological Chemistry

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Regulation of cartilage-specif ...... mide phosphoribosyltransferase

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David J Hall

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Eun-Jin Lee

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Viktoria Gagarina

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P2860

Negative control of p53 by Sir2alpha promotes cell survival under stress

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.

Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state

A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene

Histone deacetylases (HDACs): characterization of the classical HDAC family

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption

Structure and autoregulation of the yeast Hst2 homolog of Sir2

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

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36300-36310

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scholarly article

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10.1074/JBC.M803196200

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52

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283

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Mona Dvir-Ginzberg

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2008-10-28T00:00:00Z

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