Rapid generation of novel models of RAG1 deficiency by CRISPR/Cas9-induced mutagenesis in murine zygotes.
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CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome.A novel mutation in nuclear prelamin a recognition factor-like causes diffuse pulmonary arteriovenous malformationsHypomorphic Rag1 mutations alter the pre-immune repertoire at early stages of lymphoid development.
P2860
Rapid generation of novel models of RAG1 deficiency by CRISPR/Cas9-induced mutagenesis in murine zygotes.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 12 February 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Rapid generation of novel mode ...... mutagenesis in murine zygotes.
@en
Rapid generation of novel mode ...... mutagenesis in murine zygotes.
@nl
type
label
Rapid generation of novel mode ...... mutagenesis in murine zygotes.
@en
Rapid generation of novel mode ...... mutagenesis in murine zygotes.
@nl
prefLabel
Rapid generation of novel mode ...... mutagenesis in murine zygotes.
@en
Rapid generation of novel mode ...... mutagenesis in murine zygotes.
@nl
P2093
P2860
P356
P1433
P1476
Rapid generation of novel mode ...... mutagenesis in murine zygotes.
@en
P2093
John Manis
Kelly Capuder
Kiran Musunuru
Lisa Ott de Bruin
Luigi Notarangelo
Maddalena Antolini
Martin Gellert
Robin Meyers
P2860
P304
12962-12974
P356
10.18632/ONCOTARGET.7341
P407
P50
P577
2016-02-12T00:00:00Z