Physiological assembly and activity of human telomerase complexes
about
Specificity and stoichiometry of subunit interactions in the human telomerase holoenzyme assembled in vivoDNA rearrangements directed by non-coding RNAs in ciliatesStructured non-coding RNAs and the RNP RenaissanceSolution structure and dynamics of the wild-type pseudoknot of human telomerase RNANoncoding RNA control of cellular senescenceLong Non-Coding RNAs as Master Regulators in Cardiovascular DiseasesBioinformatics tools and novel challenges in long non-coding RNAs (lncRNAs) functional analysisEffect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNAStructurally conserved five nucleotide bulge determines the overall topology of the core domain of human telomerase RNAMolecular mechanisms of long noncoding RNAsPOT1-TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation.An RPA-related sequence-specific DNA-binding subunit of telomerase holoenzyme is required for elongation processivity and telomere maintenance.Investigation of human telomerase holoenzyme assembly, activity, and processivity using disease-linked subunit variants.The emerging role of pseudogene expressed non-coding RNAs in cellular functionsArchitecture of human telomerase RNA.Targeting DNA-PKcs and telomerase in brain tumour cells.Genetic Variations in Telomere Maintenance, with Implications on Tissue Renewal Capacity and Chronic Disease Pathologies.Long noncoding RNAs(lncRNAs) and the molecular hallmarks of aging.Human telomerase model shows the role of the TEN domain in advancing the double helix for the next polymerization step.Differential expression profile of long non-coding RNAs during differentiation of cardiomyocytes.Single-stranded DNA repeat synthesis by telomeraseThe DEAH-box RNA helicase RHAU binds an intramolecular RNA G-quadruplex in TERC and associates with telomerase holoenzymeRNA/DNA hybrid binding affinity determines telomerase template-translocation efficiency.Native gel electrophoresis of human telomerase distinguishes active complexes with or without dyskerin.Budding yeast telomerase RNA transcription termination is dictated by the Nrd1/Nab3 non-coding RNA termination pathway.Dynamics of Human Telomerase Holoenzyme Assembly and Subunit Exchange across the Cell Cycle.The catalytic and the RNA subunits of human telomerase are required to immortalize equid primary fibroblasts.Biogenesis of telomerase ribonucleoproteinsControl of telomerase action at human telomeresA trans-spliced telomerase RNA dictates telomere synthesis in Trypanosoma bruceiDisease-associated human telomerase RNA variants show loss of function for telomere synthesis without dominant-negative interference.Long noncoding RNA: a new player of heart failure?Chromosome end maintenance by telomerase.The Conservation and Function of RNA Secondary Structure in Plants.Targeting telomerase in hematologic malignancy.Telomerase: an RNP enzyme synthesizes DNA.Human telomerase activity regulation.TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome endsHarnessing fetal and adult genetic reprograming for therapy of heart disease.Inhibition of telomerase activity preferentially targets aldehyde dehydrogenase-positive cancer stem-like cells in lung cancer.
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Physiological assembly and activity of human telomerase complexes
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 30 October 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Physiological assembly and activity of human telomerase complexes
@en
Physiological assembly and activity of human telomerase complexes.
@nl
type
label
Physiological assembly and activity of human telomerase complexes
@en
Physiological assembly and activity of human telomerase complexes.
@nl
prefLabel
Physiological assembly and activity of human telomerase complexes
@en
Physiological assembly and activity of human telomerase complexes.
@nl
P2860
P1476
Physiological assembly and activity of human telomerase complexes
@en
P2093
Kathleen Collins
P2860
P356
10.1016/J.MAD.2007.10.008
P577
2007-10-30T00:00:00Z