Does a sentinel or a subset of short telomeres determine replicative senescence?
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Predicting Survival from Telomere Length versus Conventional Predictors: A Multinational Population-Based Cohort StudyFive dysfunctional telomeres predict onset of senescence in human cellsTelomere dysfunction and cell survival: roles for distinct TIN2-containing complexesMarkers of cellular senescence. Telomere shortening as a marker of cellular senescenceDo telomeres adapt to physiological stress? Exploring the effect of exercise on telomere length and telomere-related proteinsPolymerase epsilon is required to maintain replicative senescence.Telomeres and Telomerase in Cardiovascular DiseasesHuman subtelomeres are hot spots of interchromosomal recombination and segmental duplicationMitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence.Telomere length regulates ISG15 expression in human cellsSubtelomeric CTCF and cohesin binding site organization using improved subtelomere assemblies and a novel annotation pipeline.Human telomeres maintain their overhang length at senescence.TRIP6 and LPP, but not Zyxin, are present at a subset of telomeres in human cells.Quantitative telomerase enzyme activity determination using droplet digital PCR with single cell resolution.DNA damage-induced phosphorylation of the human telomere-associated protein TRF2.ELISA for aging biomarkers induced by telomere dysfunction in human plasma.Stable cellular senescence is associated with persistent DDR activationThe presence of telomere fusion in sporadic colon cancer independently of disease stage, TP53/KRAS mutation status, mean telomere length, and telomerase activityIrreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing.Unraveling the pathogenesis of Hoyeraal-Hreidarsson syndrome, a complex telomere biology disorderTelomere position effect: regulation of gene expression with progressive telomere shortening over long distances.Chromosome arm-specific long telomeres: a new clonal event in primary chronic myelogenous leukemia cells.Establishment of clonal myogenic cell lines from severely affected dystrophic muscles - CDK4 maintains the myogenic population.Dyslipidemia and chronic inflammation markers are correlated with telomere length shortening in Cushing's syndrome.Telomere dynamics in rhesus monkeys: no apparent effect of caloric restriction.Telomere flip-flop: an unfolding passage to senescence.Maintaining the end: roles of telomere proteins in end-protection, telomere replication and length regulationTelomere length on chromosome 17q shortens more than global telomere length in the development of breast cancer.Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeresGSE4, a Small Dyskerin- and GSE24.2-Related Peptide, Induces Telomerase Activity, Cell Proliferation and Reduces DNA Damage, Oxidative Stress and Cell Senescence in Dyskerin Mutant CellsHeritability of telomere length in a study of long-lived families.The distribution pattern of critically short telomeres in human osteoarthritic knees.Mechanisms of telomere loss and their consequences for chromosome instability.The telomere length dynamic and methods of its assessment.DNA damage, cellular senescence and organismal ageing: causal or correlative?DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?Accelerated telomere shortening and replicative senescence in human fibroblasts overexpressing mutant and wild-type lamin A.CRISPR-CAS9 D10A nickase target-specific fluorescent labeling of double strand DNA for whole genome mapping and structural variation analysis.The potential effect of fibroblast senescence on wound healing and the chronic wound environment.Telomeres and human somatic fitness.
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Does a sentinel or a subset of short telomeres determine replicative senescence?
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 04 June 2004
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Does a sentinel or a subset of short telomeres determine replicative senescence?
@en
Does a sentinel or a subset of short telomeres determine replicative senescence?
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type
label
Does a sentinel or a subset of short telomeres determine replicative senescence?
@en
Does a sentinel or a subset of short telomeres determine replicative senescence?
@nl
prefLabel
Does a sentinel or a subset of short telomeres determine replicative senescence?
@en
Does a sentinel or a subset of short telomeres determine replicative senescence?
@nl
P2093
P2860
P356
P1476
Does a sentinel or a subset of short telomeres determine replicative senescence?
@en
P2093
Jerry W Shay
Sergei M Gryaznov
P2860
P304
P356
10.1091/MBC.E04-03-0207
P577
2004-06-04T00:00:00Z