BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers
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Genetics and immunity in the era of single-cell genomicsTargeting PI3K in cancer: impact on tumor cells, their protective stroma, angiogenesis and immunotherapyMiR-130a-3p inhibits the viability, proliferation, invasion, and cell cycle, and promotes apoptosis of nasopharyngeal carcinoma cells by suppressing BACH2 expression.Bach2-Batf interactions control Th2-type immune response by regulating the IL-4 amplification loop.Human Stem Cell-like Memory T Cells Are Maintained in a State of Dynamic Flux.Divide, Conquer, and Sense: CD8+CD28- T Cells in Perspective.T Cell Fates Zipped Up: How the Bach2 Basic Leucine Zipper Transcriptional Repressor Directs T Cell Differentiation and Function.Clinical use of PI3K inhibitors in B-cell lymphoid malignancies: today and tomorrow.The Principles of Engineering Immune Cells to Treat Cancer.BACH transcription factors in innate and adaptive immunity.HIV-1-mediated insertional activation of STAT5B and BACH2 trigger viral reservoir in T regulatory cells.BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency.JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation.Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing.Bach2 represses the AP-1-driven induction of interleukin-2 gene transcription in CD4＋ T cellsInhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy.FOXO1 opposition of CD8+ T cell effector programming confers early memory properties and phenotypic diversity.The mTOR-Bach2 Cascade Controls Cell Cycle and Class Switch Recombination during B Cell Differentiation.Inflammatory responses induce an identity crisis of alveolar macrophages, leading to pulmonary alveolar proteinosis.Association of increased eomesodermin, BCL6, and granzyme B expression with major clinical manifestations of Hashimoto's thyroiditis - an observational study.ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8+ T cell fates.Bach2 is required for B cell and T cell memory differentiation.Bach2 repression mediates Th17 cell induced inflammation and associates with clinical features of advanced disease in chronic pancreatitis.SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylationEpigenetic control of innate and adaptive immune memoryGenetic Defects in Phosphoinositide 3-Kinase δ Influence CD8 T Cell Survival, Differentiation, and FunctionThe Role of BACH2 in T Cells in Experimental Malaria Caused by AS
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BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 09 May 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
BACH2 regulates CD8
@nl
BACH2 regulates CD8(+) T cell ...... s of AP-1 factors to enhancers
@en
type
label
BACH2 regulates CD8
@nl
BACH2 regulates CD8(+) T cell ...... s of AP-1 factors to enhancers
@en
prefLabel
BACH2 regulates CD8
@nl
BACH2 regulates CD8(+) T cell ...... s of AP-1 factors to enhancers
@en
P2093
P2860
P50
P356
P1433
P1476
BACH2 regulates CD8(+) T cell ...... s of AP-1 factors to enhancers
@en
P2093
Akihiko Muto
Giulia Fabozzi
Jenny H Pan
John J O'Shea
Luca Gattinoni
Madhusudhanan Sukumar
Robert L Eil
Rosanne Spolski
P2860
P304
P356
10.1038/NI.3441
P407
P50
P577
2016-05-09T00:00:00Z